Format
Sort by
Items per page

Send to

Choose Destination

Links from PubMed

Items: 1 to 20 of 98

1.

Mfge8 promotes obesity by mediating the uptake of dietary fats and serum fatty acids.

Khalifeh-Soltani A, McKleroy W, Sakuma S, Cheung YY, Tharp K, Qiu Y, Turner SM, Chawla A, Stahl A, Atabai K.

Nat Med. 2014 Feb;20(2):175-83. doi: 10.1038/nm.3450. Epub 2014 Jan 19.

2.

Mfge8 suppresses airway hyperresponsiveness in asthma by regulating smooth muscle contraction.

Kudo M, Khalifeh Soltani SM, Sakuma SA, McKleroy W, Lee TH, Woodruff PG, Lee JW, Huang K, Chen C, Arjomandi M, Huang X, Atabai K.

Proc Natl Acad Sci U S A. 2013 Jan 8;110(2):660-5. doi: 10.1073/pnas.1216673110. Epub 2012 Dec 26.

3.

Mfge8 diminishes the severity of tissue fibrosis in mice by binding and targeting collagen for uptake by macrophages.

Atabai K, Jame S, Azhar N, Kuo A, Lam M, McKleroy W, Dehart G, Rahman S, Xia DD, Melton AC, Wolters P, Emson CL, Turner SM, Werb Z, Sheppard D.

J Clin Invest. 2009 Dec;119(12):3713-22. doi: 10.1172/JCI40053. Epub 2009 Nov 2.

4.

Milk fat globule--epidermal growth factor--factor VIII (MFGE8)/lactadherin promotes bladder tumor development.

Sugano G, Bernard-Pierrot I, Laé M, Battail C, Allory Y, Stransky N, Krumeich S, Lepage ML, Maille P, Donnadieu MH, Abbou CC, Benhamou S, Lebret T, Sastre-Garau X, Amigorena S, Radvanyi F, Théry C.

Oncogene. 2011 Feb 10;30(6):642-53. doi: 10.1038/onc.2010.446. Epub 2010 Oct 18.

PMID:
20956946
5.

Smad3 deficiency in mice protects against insulin resistance and obesity induced by a high-fat diet.

Tan CK, Leuenberger N, Tan MJ, Yan YW, Chen Y, Kambadur R, Wahli W, Tan NS.

Diabetes. 2011 Feb;60(2):464-76. doi: 10.2337/db10-0801.

6.

AMPD1 regulates mTORC1-p70 S6 kinase axis in the control of insulin sensitivity in skeletal muscle.

Tandelilin AA, Hirase T, Hudoyo AW, Cheng J, Toyama K, Morisaki H, Morisaki T.

BMC Endocr Disord. 2015 Mar 27;15:11. doi: 10.1186/s12902-015-0010-9. Erratum in: BMC Endocr Disord. 2015;15:80.

7.

Follicular dendritic cells control engulfment of apoptotic bodies by secreting Mfge8.

Kranich J, Krautler NJ, Heinen E, Polymenidou M, Bridel C, Schildknecht A, Huber C, Kosco-Vilbois MH, Zinkernagel R, Miele G, Aguzzi A.

J Exp Med. 2008 Jun 9;205(6):1293-302. doi: 10.1084/jem.20071019. Epub 2008 May 19.

8.

Fisetin regulates obesity by targeting mTORC1 signaling.

Jung CH, Kim H, Ahn J, Jeon TI, Lee DH, Ha TY.

J Nutr Biochem. 2013 Aug;24(8):1547-54. doi: 10.1016/j.jnutbio.2013.01.003. Epub 2013 Mar 18.

PMID:
23517912
9.

MFGE8 does not orchestrate clearance of apoptotic neurons in a mouse model of Parkinson's disease.

Kinugawa K, Monnet Y, Lu L, Bekaert AJ, Théry C, Mallat Z, Hirsch EC, Hunot S.

Neurobiol Dis. 2013 Mar;51:192-201. doi: 10.1016/j.nbd.2012.11.010. Epub 2012 Nov 27.

PMID:
23194669
10.

MFGE8 inhibits inflammasome-induced IL-1β production and limits postischemic cerebral injury.

Deroide N, Li X, Lerouet D, Van Vré E, Baker L, Harrison J, Poittevin M, Masters L, Nih L, Margaill I, Iwakura Y, Ryffel B, Pocard M, Tedgui A, Kubis N, Mallat Z.

J Clin Invest. 2013 Mar;123(3):1176-81. doi: 10.1172/JCI65167. Epub 2013 Feb 1.

11.

MFGE8 does not influence chorio-retinal homeostasis or choroidal neovascularization in vivo.

Raoul W, Poupel L, Tregouet DA, Lavalette S, Camelo S, Keller N, Krumeich S, Calippe B, Guillonneau X, Behar-Cohen F, Cohen SY, Baatz H, Combadière C, Théry C, Sennlaub F.

PLoS One. 2012;7(3):e33244. doi: 10.1371/journal.pone.0033244. Epub 2012 Mar 15.

12.

Tumor progression locus 2 (TPL2) regulates obesity-associated inflammation and insulin resistance.

Perfield JW 2nd, Lee Y, Shulman GI, Samuel VT, Jurczak MJ, Chang E, Xie C, Tsichlis PN, Obin MS, Greenberg AS.

Diabetes. 2011 Apr;60(4):1168-76. doi: 10.2337/db10-0715. Epub 2011 Feb 23.

13.

MFGE8/Integrin β3 pathway alleviates apoptosis and inflammation in early brain injury after subarachnoid hemorrhage in rats.

Liu F, Chen Y, Hu Q, Li B, Tang J, He Y, Guo Z, Feng H, Tang J, Zhang JH.

Exp Neurol. 2015 Oct;272:120-7. doi: 10.1016/j.expneurol.2015.04.016. Epub 2015 May 1.

14.

Mitochondrial dysfunction induces triglyceride accumulation in 3T3-L1 cells: role of fatty acid beta-oxidation and glucose.

Vankoningsloo S, Piens M, Lecocq C, Gilson A, De Pauw A, Renard P, Demazy C, Houbion A, Raes M, Arnould T.

J Lipid Res. 2005 Jun;46(6):1133-49. Epub 2005 Mar 1.

15.

Novel proapoptotic effect of hepatocyte growth factor: synergy with palmitate to cause pancreatic {beta}-cell apoptosis.

González-Pertusa JA, Dubé J, Valle SR, Rosa TC, Takane KK, Mellado-Gil JM, Perdomo G, Vasavada RC, García-Ocaña A.

Endocrinology. 2010 Apr;151(4):1487-98. doi: 10.1210/en.2009-0975. Epub 2010 Feb 22.

16.

Tyrosylprotein sulfotransferase-2 expression is required for sulfation of RNase 9 and Mfge8 in vivo.

Hoffhines AJ, Jen CH, Leary JA, Moore KL.

J Biol Chem. 2009 Jan 30;284(5):3096-105. doi: 10.1074/jbc.M808434200. Epub 2008 Dec 1.

17.

Glucosamine enhances body weight gain and reduces insulin response in mice fed chow diet but mitigates obesity, insulin resistance and impaired glucose tolerance in mice high-fat diet.

Hwang JS, Park JW, Nam MS, Cho H, Han IO.

Metabolism. 2015 Mar;64(3):368-79. doi: 10.1016/j.metabol.2014.11.005. Epub 2014 Nov 20.

PMID:
25516476
18.

FAT/CD36-mediated long-chain fatty acid uptake in adipocytes requires plasma membrane rafts.

Pohl J, Ring A, Korkmaz U, Ehehalt R, Stremmel W.

Mol Biol Cell. 2005 Jan;16(1):24-31. Epub 2004 Oct 20.

19.

Alterations to mTORC1 signaling in the skeletal muscle differentially affect whole-body metabolism.

Guridi M, Kupr B, Romanino K, Lin S, Falcetta D, Tintignac L, Rüegg MA.

Skelet Muscle. 2016 Mar 21;6:13. doi: 10.1186/s13395-016-0084-8. eCollection 2016.

20.

Macrophage mTORC1 disruption reduces inflammation and insulin resistance in obese mice.

Jiang H, Westerterp M, Wang C, Zhu Y, Ai D.

Diabetologia. 2014 Nov;57(11):2393-404. doi: 10.1007/s00125-014-3350-5. Epub 2014 Aug 14.

PMID:
25120095

Supplemental Content

Support Center