Format
Sort by
Items per page

Send to

Choose Destination

Links from PubMed

Items: 1 to 20 of 127

1.

Ablation of PRDM16 and beige adipose causes metabolic dysfunction and a subcutaneous to visceral fat switch.

Cohen P, Levy JD, Zhang Y, Frontini A, Kolodin DP, Svensson KJ, Lo JC, Zeng X, Ye L, Khandekar MJ, Wu J, Gunawardana SC, Banks AS, Camporez JP, Jurczak MJ, Kajimura S, Piston DW, Mathis D, Cinti S, Shulman GI, Seale P, Spiegelman BM.

Cell. 2014 Jan 16;156(1-2):304-16. doi: 10.1016/j.cell.2013.12.021.

2.

Resveratrol derivative BTM-0512 mitigates obesity by promoting beige remodeling of subcutaneous preadipocytes.

Li Q, Wang K, Ma Y, Qin C, Dong C, Jin P, Wu Y, Xiong X, Li N, Hu C, Peng J, Yang Z.

Acta Biochim Biophys Sin (Shanghai). 2017 Apr 1;49(4):318-327. doi: 10.1093/abbs/gmx009.

PMID:
28338809
3.

Fetal development of subcutaneous white adipose tissue is dependent on Zfp423.

Shao M, Hepler C, Vishvanath L, MacPherson KA, Busbuso NC, Gupta RK.

Mol Metab. 2016 Nov 21;6(1):111-124. doi: 10.1016/j.molmet.2016.11.009. eCollection 2017 Jan.

4.

Transcription factor Hlx controls a systematic switch from white to brown fat through Prdm16-mediated co-activation.

Huang L, Pan D, Chen Q, Zhu LJ, Ou J, Wabitsch M, Wang YX.

Nat Commun. 2017 Jul 12;8(1):68. doi: 10.1038/s41467-017-00098-2.

5.

Prdm16 determines the thermogenic program of subcutaneous white adipose tissue in mice.

Seale P, Conroe HM, Estall J, Kajimura S, Frontini A, Ishibashi J, Cohen P, Cinti S, Spiegelman BM.

J Clin Invest. 2011 Jan;121(1):96-105. doi: 10.1172/JCI44271. Epub 2010 Dec 1.

6.

Lipopolysaccharide-binding protein is a negative regulator of adipose tissue browning in mice and humans.

Gavaldà-Navarro A, Moreno-Navarrete JM, Quesada-López T, Cairó M, Giralt M, Fernández-Real JM, Villarroya F.

Diabetologia. 2016 Oct;59(10):2208-18. doi: 10.1007/s00125-016-4028-y. Epub 2016 Jun 25.

PMID:
27344313
7.

Rorα deficiency and decreased adiposity are associated with induction of thermogenic gene expression in subcutaneous white adipose and brown adipose tissue.

Lau P, Tuong ZK, Wang SC, Fitzsimmons RL, Goode JM, Thomas GP, Cowin GJ, Pearen MA, Mardon K, Stow JL, Muscat GE.

Am J Physiol Endocrinol Metab. 2015 Jan 15;308(2):E159-71. doi: 10.1152/ajpendo.00056.2014. Epub 2014 Nov 25.

8.

Role of PRDM16 in the activation of brown fat programming. Relevance to the development of obesity.

Becerril S, Gómez-Ambrosi J, Martín M, Moncada R, Sesma P, Burrell MA, Frühbeck G.

Histol Histopathol. 2013 Nov;28(11):1411-25. doi: 10.14670/HH-28.1411. Epub 2013 Jun 17. Review.

PMID:
23771475
9.

Zbtb7b engages the long noncoding RNA Blnc1 to drive brown and beige fat development and thermogenesis.

Li S, Mi L, Yu L, Yu Q, Liu T, Wang GX, Zhao XY, Wu J, Lin JD.

Proc Natl Acad Sci U S A. 2017 Aug 22;114(34):E7111-E7120. doi: 10.1073/pnas.1703494114. Epub 2017 Aug 7.

10.

Obesity-Associated miR-199a/214 Cluster Inhibits Adipose Browning via PRDM16-PGC-1α Transcriptional Network.

He L, Tang M, Xiao T, Liu H, Liu W, Li G, Zhang F, Xiao Y, Zhou Z, Liu F, Hu F.

Diabetes. 2018 Dec;67(12):2585-2600. doi: 10.2337/db18-0626. Epub 2018 Oct 2.

11.

Erythropoietin (EPO) ameliorates obesity and glucose homeostasis by promoting thermogenesis and endocrine function of classical brown adipose tissue (BAT) in diet-induced obese mice.

Kodo K, Sugimoto S, Nakajima H, Mori J, Itoh I, Fukuhara S, Shigehara K, Nishikawa T, Kosaka K, Hosoi H.

PLoS One. 2017 Mar 13;12(3):e0173661. doi: 10.1371/journal.pone.0173661. eCollection 2017.

12.

MiR-27 orchestrates the transcriptional regulation of brown adipogenesis.

Sun L, Trajkovski M.

Metabolism. 2014 Feb;63(2):272-82. doi: 10.1016/j.metabol.2013.10.004. Epub 2013 Oct 24.

PMID:
24238035
13.

Repression of Adipose Tissue Fibrosis through a PRDM16-GTF2IRD1 Complex Improves Systemic Glucose Homeostasis.

Hasegawa Y, Ikeda K, Chen Y, Alba DL, Stifler D, Shinoda K, Hosono T, Maretich P, Yang Y, Ishigaki Y, Chi J, Cohen P, Koliwad SK, Kajimura S.

Cell Metab. 2018 Jan 9;27(1):180-194.e6. doi: 10.1016/j.cmet.2017.12.005.

14.

Adipocyte-specific Hypoxia-inducible gene 2 promotes fat deposition and diet-induced insulin resistance.

DiStefano MT, Roth Flach RJ, Senol-Cosar O, Danai LV, Virbasius JV, Nicoloro SM, Straubhaar J, Dagdeviren S, Wabitsch M, Gupta OT, Kim JK, Czech MP.

Mol Metab. 2016 Sep 28;5(12):1149-1161. doi: 10.1016/j.molmet.2016.09.009. eCollection 2016 Dec.

15.

The long noncoding RNA Blnc1 orchestrates homeostatic adipose tissue remodeling to preserve metabolic health.

Zhao XY, Li S, DelProposto JL, Liu T, Mi L, Porsche C, Peng X, Lumeng CN, Lin JD.

Mol Metab. 2018 Aug;14:60-70. doi: 10.1016/j.molmet.2018.06.005. Epub 2018 Jun 8.

16.

Eicosapentaenoic acid regulates brown adipose tissue metabolism in high-fat-fed mice and in clonal brown adipocytes.

Pahlavani M, Razafimanjato F, Ramalingam L, Kalupahana NS, Moussa H, Scoggin S, Moustaid-Moussa N.

J Nutr Biochem. 2017 Jan;39:101-109. doi: 10.1016/j.jnutbio.2016.08.012. Epub 2016 Sep 22.

17.

PexRAP Inhibits PRDM16-Mediated Thermogenic Gene Expression.

Lodhi IJ, Dean JM, He A, Park H, Tan M, Feng C, Song H, Hsu FF, Semenkovich CF.

Cell Rep. 2017 Sep 19;20(12):2766-2774. doi: 10.1016/j.celrep.2017.08.077.

18.

Three-Dimensional Adipose Tissue Imaging Reveals Regional Variation in Beige Fat Biogenesis and PRDM16-Dependent Sympathetic Neurite Density.

Chi J, Wu Z, Choi CHJ, Nguyen L, Tegegne S, Ackerman SE, Crane A, Marchildon F, Tessier-Lavigne M, Cohen P.

Cell Metab. 2018 Jan 9;27(1):226-236.e3. doi: 10.1016/j.cmet.2017.12.011.

19.

Directing visceral white adipocyte precursors to a thermogenic adipocyte fate improves insulin sensitivity in obese mice.

Hepler C, Shao M, Xia JY, Ghaben AL, Pearson MJ, Vishvanath L, Sharma AX, Morley TS, Holland WL, Gupta RK.

Elife. 2017 Jul 19;6. pii: e27669. doi: 10.7554/eLife.27669.

20.

Switching harmful visceral fat to beneficial energy combustion improves metabolic dysfunctions.

Yang X, Sui W, Zhang M, Dong M, Lim S, Seki T, Guo Z, Fischer C, Lu H, Zhang C, Yang J, Zhang M, Wang Y, Cao C, Gao Y, Zhao X, Sun M, Sun Y, Zhuang R, Samani NJ, Zhang Y, Cao Y.

JCI Insight. 2017 Feb 23;2(4):e89044. doi: 10.1172/jci.insight.89044.

Supplemental Content

Support Center