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Items: 1 to 20 of 219

1.

MHY-449, a novel dihydrobenzofuro[4,5-b][1,8] naphthyridin-6-one derivative, induces apoptotic cell death through modulation of Akt/FoxO1 and ERK signaling in PC3 human prostate cancer cells.

Lee SH, Kang YJ, Sung B, Kim DH, Lim HS, Kim HR, Kim SJ, Yoon JH, Moon HR, Chung HY, Kim ND.

Int J Oncol. 2014 Mar;44(3):905-11. doi: 10.3892/ijo.2014.2257. Epub 2014 Jan 10.

PMID:
24424889
2.

Novel dihydrobenzofuro[4,5-b][1,8]naphthyridin-6-one derivative, MHY-449, induces apoptosis and cell cycle arrest in HCT116 human colon cancer cells.

Hwang HJ, Kang YJ, Hossain MA, Kim DH, Jang JY, Lee SH, Yoon JH, Moon HR, Kim HS, Chung HY, Kim ND.

Int J Oncol. 2012 Dec;41(6):2057-64. doi: 10.3892/ijo.2012.1659. Epub 2012 Oct 11.

PMID:
23064444
3.

Novel dihydrobenzofuro[4,5-b][1,8]naphthyridin-6-one derivative, MHY-449, induces cell cycle arrest and apoptosis via the downregulation of Akt in human lung cancer cells.

Lim HS, Kang YJ, Sung B, Kim SH, Kim MJ, Kim HR, Kim SJ, Choi YH, Moon HR, Chung HY, Kim ND.

Oncol Rep. 2015 Nov;34(5):2431-8. doi: 10.3892/or.2015.4208. Epub 2015 Aug 19.

PMID:
26324335
4.

MHY-449, a novel dihydrobenzofuro[4,5-b][1,8]naphthyridin-6-one derivative, mediates oxidative stress-induced apoptosis in AGS human gastric cancer cells.

Kim SH, Kang YJ, Sung B, Kim DH, Lim HS, Kim HR, Kim SJ, Yoon JH, Moon HR, Chung HY, Kim ND.

Oncol Rep. 2015 Jul;34(1):288-94. doi: 10.3892/or.2015.3984. Epub 2015 May 18.

PMID:
25998412
5.
6.

Targeting the Vav3 oncogene enhances docetaxel-induced apoptosis through the inhibition of androgen receptor phosphorylation in LNCaP prostate cancer cells under chronic hypoxia.

Nomura T, Yamasaki M, Hirai K, Inoue T, Sato R, Matsuura K, Moriyama M, Sato F, Mimata H.

Mol Cancer. 2013 Apr 8;12:27. doi: 10.1186/1476-4598-12-27.

7.

Purified vitexin compound 1 induces apoptosis through activation of FOXO3a in hepatocellular carcinoma.

Wang JG, Zheng XX, Zeng GY, Zhou YJ, Yuan H.

Oncol Rep. 2014 Jan;31(1):488-96. doi: 10.3892/or.2013.2855. Epub 2013 Nov 15.

PMID:
24247909
9.

ProstaCaid induces G2/M cell cycle arrest and apoptosis in human and mouse androgen-dependent and-independent prostate cancer cells.

Yan J, Katz AE.

Integr Cancer Ther. 2010 Jun;9(2):186-96. doi: 10.1177/1534735410371478.

PMID:
20587444
11.

Curcumin induces apoptosis in pancreatic cancer cells through the induction of forkhead box O1 and inhibition of the PI3K/Akt pathway.

Zhao Z, Li C, Xi H, Gao Y, Xu D.

Mol Med Rep. 2015 Oct;12(4):5415-22. doi: 10.3892/mmr.2015.4060. Epub 2015 Jul 8.

PMID:
26166196
12.

Mahanine inhibits growth and induces apoptosis in prostate cancer cells through the deactivation of Akt and activation of caspases.

Sinha S, Pal BC, Jagadeesh S, Banerjee PP, Bandyopadhaya A, Bhattacharya S.

Prostate. 2006 Sep 1;66(12):1257-65.

PMID:
16683271
13.

Zerumbone suppresses IKKα, Akt, and FOXO1 activation, resulting in apoptosis of GBM 8401 cells.

Weng HY, Hsu MJ, Wang CC, Chen BC, Hong CY, Chen MC, Chiu WT, Lin CH.

J Biomed Sci. 2012 Oct 5;19:86. doi: 10.1186/1423-0127-19-86.

14.

An α-quaternary chiral latam derivative, YH-304 as a novel broad-spectrum anticancer agent.

Hwang SJ, Park HG, Park Y, Lee HJ.

Int J Oncol. 2016 Dec;49(6):2480-2486. doi: 10.3892/ijo.2016.3726. Epub 2016 Oct 11.

PMID:
27748805
15.

Tanshinone IIA induces mitochondria dependent apoptosis in prostate cancer cells in association with an inhibition of phosphoinositide 3-kinase/AKT pathway.

Won SH, Lee HJ, Jeong SJ, Lee HJ, Lee EO, Jung DB, Shin JM, Kwon TR, Yun SM, Lee MH, Choi SH, Lü J, Kim SH.

Biol Pharm Bull. 2010;33(11):1828-34.

16.

R115777 (Zarnestra)/Zoledronic acid (Zometa) cooperation on inhibition of prostate cancer proliferation is paralleled by Erk/Akt inactivation and reduced Bcl-2 and bad phosphorylation.

Caraglia M, Marra M, Leonetti C, Meo G, D'Alessandro AM, Baldi A, Santini D, Tonini G, Bertieri R, Zupi G, Budillon A, Abbruzzese A.

J Cell Physiol. 2007 May;211(2):533-43.

PMID:
17192846
17.

A novel hydroxamic acid compound, BMD188, demonstrates anti-prostate cancer effects by inducing apoptosis. I: In vitro studies.

Li L, Zhu Z, Joshi B, Porter AT, Tang DG.

Anticancer Res. 1999 Jan-Feb;19(1A):51-60.

PMID:
10226524
18.

Inhibition of AKT/FoxO3a signaling induced PUMA expression in response to p53-independent cytotoxic effects of H1: A derivative of tetrandrine.

Zhang YX, Liu XM, Wang J, Li J, Liu Y, Zhang H, Yu XW, Wei N.

Cancer Biol Ther. 2015;16(6):965-75. doi: 10.1080/15384047.2015.1040950. Epub 2015 Apr 20.

19.

Roles of the PI3K/Akt pathway and autophagy in TLR3 signaling-induced apoptosis and growth arrest of human prostate cancer cells.

Harashima N, Inao T, Imamura R, Okano S, Suda T, Harada M.

Cancer Immunol Immunother. 2012 May;61(5):667-76. doi: 10.1007/s00262-011-1132-1. Epub 2011 Oct 29.

PMID:
22038398
20.

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