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The effect of the G1-S transition checkpoint on an age structured cell cycle model.

Chaffey GS, Lloyd DJ, Skeldon AC, Kirkby NF.

PLoS One. 2014 Jan 9;9(1):e83477. doi: 10.1371/journal.pone.0083477. eCollection 2014.


Modelling the onset of senescence at the G1/S cell cycle checkpoint.

Mombach JC, Bugs CA, Chaouiya C.

BMC Genomics. 2014;15 Suppl 7:S7. doi: 10.1186/1471-2164-15-S7-S7. Epub 2014 Oct 27.


Lack of a p21waf1/cip -dependent G1/S checkpoint in neural stem and progenitor cells after DNA damage in vivo.

Roque T, Haton C, Etienne O, Chicheportiche A, Rousseau L, Martin L, Mouthon MA, Boussin FD.

Stem Cells. 2012 Mar;30(3):537-47. doi: 10.1002/stem.1010.


The STIM1-Orai1 pathway of store-operated Ca2+ entry controls the checkpoint in cell cycle G1/S transition.

Chen YW, Chen YF, Chen YT, Chiu WT, Shen MR.

Sci Rep. 2016 Feb 26;6:22142. doi: 10.1038/srep22142.


Identification of age-structured models: cell cycle phase transitions.

Sherer E, Tocce E, Hannemann RE, Rundell AE, Ramkrishna D.

Biotechnol Bioeng. 2008 Mar 1;99(4):960-74.


Novel phase I study combining G1 phase, S phase, and G2/M phase cell cycle inhibitors in patients with advanced malignancies.

Jain RK, Hong DS, Naing A, Wheler J, Helgason T, Shi NY, Gad Y, Kurzrock R.

Cell Cycle. 2015;14(21):3434-40. doi: 10.1080/15384101.2015.1090065. Erratum in: Cell Cycle. 2015;14(24):3986. Dosage error in article text.


Glypican-1 stimulates Skp2 autoinduction loop and G1/S transition in endothelial cells.

Qiao D, Meyer K, Friedl A.

J Biol Chem. 2012 Feb 17;287(8):5898-909. doi: 10.1074/jbc.M111.325282. Epub 2011 Dec 27. Retraction in: J Biol Chem. 2016 Jul 1;291(27):14389.


Identification of herpesvirus proteins that contribute to G1/S arrest.

Paladino P, Marcon E, Greenblatt J, Frappier L.

J Virol. 2014 Apr;88(8):4480-92. doi: 10.1128/JVI.00059-14. Epub 2014 Feb 5.


A checkpoints capturing timing-robust Boolean model of the budding yeast cell cycle regulatory network.

Hong C, Lee M, Kim D, Kim D, Cho KH, Shin I.

BMC Syst Biol. 2012 Sep 28;6:129. doi: 10.1186/1752-0509-6-129.


G1 checkpoint establishment in vivo during embryonic liver development.

Wang XQ, Chan KK, Ming X, Lui VC, Poon RY, Lo CM, Norbury C, Poon RT.

BMC Dev Biol. 2014 May 19;14:23. doi: 10.1186/1471-213X-14-23.


Computational experiments reveal the efficacy of targeting CDK2 and CKIs for significantly lowering cellular senescence bar for potential cancer treatment.

Ling H, Samarasinghe S, Kulasiri D.

Biosystems. 2013 Feb;111(2):71-82. doi: 10.1016/j.biosystems.2012.12.001. Epub 2012 Dec 17.


Live imaging-based model selection reveals periodic regulation of the stochastic G1/S phase transition in vertebrate axial development.

Sugiyama M, Saitou T, Kurokawa H, Sakaue-Sawano A, Imamura T, Miyawaki A, Iimura T.

PLoS Comput Biol. 2014 Dec 4;10(12):e1003957. doi: 10.1371/journal.pcbi.1003957. eCollection 2014 Dec.


Robustness of G1/S checkpoint pathways in cell cycle regulation based on probability of DNA-damaged cells passing as healthy cells.

Ling H, Kulasiri D, Samarasinghe S.

Biosystems. 2010 Sep;101(3):213-21. doi: 10.1016/j.biosystems.2010.07.005. Epub 2010 Jul 21.


A computational model for quantitative analysis of cell cycle arrest and its contribution to overall growth inhibition by anticancer agents.

Kuh HJ, Nakagawa S, Usuda J, Yamaoka K, Saijo N, Nishio K.

Jpn J Cancer Res. 2000 Dec;91(12):1303-13.


Thymoquinone inhibits cell proliferation through regulation of G1/S phase cell cycle transition in N-nitrosodiethylamine-induced experimental rat hepatocellular carcinoma.

Raghunandhakumar S, Paramasivam A, Senthilraja S, Naveenkumar C, Asokkumar S, Binuclara J, Jagan S, Anandakumar P, Devaki T.

Toxicol Lett. 2013 Oct 23;223(1):60-72. doi: 10.1016/j.toxlet.2013.08.018. Epub 2013 Sep 3.


Sterigmatocystin induces G1 arrest in primary human esophageal epithelial cells but induces G2 arrest in immortalized cells: key mechanistic differences in these two models.

Wang J, Huang S, Xing L, Cui J, Tian Z, Shen H, Jiang X, Yan X, Wang J, Zhang X.

Arch Toxicol. 2015 Nov;89(11):2015-25. doi: 10.1007/s00204-014-1362-z. Epub 2014 Oct 8.


Mechanism-based screen for G1/S checkpoint activators identifies a selective activator of EIF2AK3/PERK signalling.

Stockwell SR, Platt G, Barrie SE, Zoumpoulidou G, Te Poele RH, Aherne GW, Wilson SC, Sheldrake P, McDonald E, Venet M, Soudy C, Elustondo F, Rigoreau L, Blagg J, Workman P, Garrett MD, Mittnacht S.

PLoS One. 2012;7(1):e28568. doi: 10.1371/journal.pone.0028568. Epub 2012 Jan 12.


G(1)/S and G(2)/M cyclin-dependent kinase activities commit cells to death in the absence of the S-phase checkpoint.

Manfrini N, Gobbini E, Baldo V, Trovesi C, Lucchini G, Longhese MP.

Mol Cell Biol. 2012 Dec;32(24):4971-85. doi: 10.1128/MCB.00956-12. Epub 2012 Oct 8.

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