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Items: 1 to 20 of 118

1.

Transcription factor 4 (TCF4) and schizophrenia: integrating the animal and the human perspective.

Quednow BB, Brzózka MM, Rossner MJ.

Cell Mol Life Sci. 2014 Aug;71(15):2815-35. doi: 10.1007/s00018-013-1553-4. Epub 2014 Jan 12. Review.

PMID:
24413739
2.

Cognitive and sensorimotor gating impairments in transgenic mice overexpressing the schizophrenia susceptibility gene Tcf4 in the brain.

Brzózka MM, Radyushkin K, Wichert SP, Ehrenreich H, Rossner MJ.

Biol Psychiatry. 2010 Jul 1;68(1):33-40. doi: 10.1016/j.biopsych.2010.03.015.

PMID:
20434134
3.

Impact of TCF4 on the genetics of schizophrenia.

Lennertz L, Quednow BB, Benninghoff J, Wagner M, Maier W, Mössner R.

Eur Arch Psychiatry Clin Neurosci. 2011 Nov;261 Suppl 2:S161-5. doi: 10.1007/s00406-011-0256-9. Epub 2011 Sep 20. Review.

PMID:
21932083
4.

Pitt-Hopkins syndrome-associated mutations in TCF4 lead to variable impairment of the transcription factor function ranging from hypomorphic to dominant-negative effects.

Sepp M, Pruunsild P, Timmusk T.

Hum Mol Genet. 2012 Jul 1;21(13):2873-88. doi: 10.1093/hmg/dds112. Epub 2012 Mar 28.

PMID:
22460224
5.

TCF4 (e2-2; ITF2): a schizophrenia-associated gene with pleiotropic effects on human disease.

Navarrete K, Pedroso I, De Jong S, Stefansson H, Steinberg S, Stefansson K, Ophoff RA, Schalkwyk LC, Collier DA.

Am J Med Genet B Neuropsychiatr Genet. 2013 Jan;162B(1):1-16. doi: 10.1002/ajmg.b.32109. Epub 2012 Nov 5. Review.

PMID:
23129290
6.

TCF4, schizophrenia, and Pitt-Hopkins Syndrome.

Blake DJ, Forrest M, Chapman RM, Tinsley CL, O'Donovan MC, Owen MJ.

Schizophr Bull. 2010 May;36(3):443-7. doi: 10.1093/schbul/sbq035. Epub 2010 Apr 26.

7.

Functional diversity of human basic helix-loop-helix transcription factor TCF4 isoforms generated by alternative 5' exon usage and splicing.

Sepp M, Kannike K, Eesmaa A, Urb M, Timmusk T.

PLoS One. 2011;6(7):e22138. doi: 10.1371/journal.pone.0022138. Epub 2011 Jul 15.

8.

Novel schizophrenia risk gene TCF4 influences verbal learning and memory functioning in schizophrenia patients.

Lennertz L, Rujescu D, Wagner M, Frommann I, Schulze-Rauschenbach S, Schuhmacher A, Landsberg MW, Franke P, Möller HJ, Wölwer W, Gaebel W, Häfner H, Maier W, Mössner R.

Neuropsychobiology. 2011;63(3):131-6. doi: 10.1159/000317844. Epub 2011 Jan 13.

9.

Association between TCF4 and schizophrenia does not exert its effect by common nonsynonymous variation or by influencing cis-acting regulation of mRNA expression in adult human brain.

Williams HJ, Moskvina V, Smith RL, Dwyer S, Russo G, Owen MJ, O'Donovan MC.

Am J Med Genet B Neuropsychiatr Genet. 2011 Dec;156B(7):781-4. doi: 10.1002/ajmg.b.31219. Epub 2011 Aug 2.

10.

Schizophrenia risk polymorphisms in the TCF4 gene interact with smoking in the modulation of auditory sensory gating.

Quednow BB, Brinkmeyer J, Mobascher A, Nothnagel M, Musso F, Gründer G, Savary N, Petrovsky N, Frommann I, Lennertz L, Spreckelmeyer KN, Wienker TF, Dahmen N, Thuerauf N, Clepce M, Kiefer F, Majic T, Mössner R, Maier W, Gallinat J, Diaz-Lacava A, Toliat MR, Thiele H, Nürnberg P, Wagner M, Winterer G.

Proc Natl Acad Sci U S A. 2012 Apr 17;109(16):6271-6. doi: 10.1073/pnas.1118051109. Epub 2012 Mar 26.

11.

TCF4 sequence variants and mRNA levels are associated with neurodevelopmental characteristics in psychotic disorders.

Wirgenes KV, Sønderby IE, Haukvik UK, Mattingsdal M, Tesli M, Athanasiu L, Sundet K, Røssberg JI, Dale AM, Brown AA, Agartz I, Melle I, Djurovic S, Andreassen OA.

Transl Psychiatry. 2012 May 8;2:e112. doi: 10.1038/tp.2012.39.

12.

The emerging roles of TCF4 in disease and development.

Forrest MP, Hill MJ, Quantock AJ, Martin-Rendon E, Blake DJ.

Trends Mol Med. 2014 Jun;20(6):322-31. doi: 10.1016/j.molmed.2014.01.010. Epub 2014 Mar 1. Review.

PMID:
24594265
13.

Deficits in trace fear memory in a mouse model of the schizophrenia risk gene TCF4.

Brzózka MM, Rossner MJ.

Behav Brain Res. 2013 Jan 15;237:348-56. doi: 10.1016/j.bbr.2012.10.001. Epub 2012 Oct 13.

PMID:
23069005
14.

TCF4 gene polymorphism is associated with cognition in patients with schizophrenia and healthy controls.

Hui L, Rao WW, Yu Q, Kou C, Wu JQ, He JC, Ye MJ, Liu JH, Xu XJ, Zheng K, Ruan LN, Liu HY, Hu WM, Shao TN, AngRabanes MB, Soares JC, Zhang XY.

J Psychiatr Res. 2015 Oct;69:95-101. doi: 10.1016/j.jpsychires.2015.07.022. Epub 2015 Jul 22.

PMID:
26343600
15.

The schizophrenia risk allele C of the TCF4 rs9960767 polymorphism disrupts sensorimotor gating in schizophrenia spectrum and healthy volunteers.

Quednow BB, Ettinger U, Mössner R, Rujescu D, Giegling I, Collier DA, Schmechtig A, Kühn KU, Möller HJ, Maier W, Wagner M, Kumari V.

J Neurosci. 2011 May 4;31(18):6684-91. doi: 10.1523/JNEUROSCI.0526-11.2011.

16.

Functional analysis of TCF4 missense mutations that cause Pitt-Hopkins syndrome.

Forrest M, Chapman RM, Doyle AM, Tinsley CL, Waite A, Blake DJ.

Hum Mutat. 2012 Dec;33(12):1676-86. doi: 10.1002/humu.22160. Epub 2012 Jul 27.

PMID:
22777675
17.

Two percent of patients suspected of having Angelman syndrome have TCF4 mutations.

Takano K, Lyons M, Moyes C, Jones J, Schwartz CE.

Clin Genet. 2010 Sep;78(3):282-8. doi: 10.1111/j.1399-0004.2010.01380.x. Epub 2010 Feb 10.

PMID:
20184619
18.

Novel comprehensive diagnostic strategy in Pitt-Hopkins syndrome: clinical score and further delineation of the TCF4 mutational spectrum.

Whalen S, Héron D, Gaillon T, Moldovan O, Rossi M, Devillard F, Giuliano F, Soares G, Mathieu-Dramard M, Afenjar A, Charles P, Mignot C, Burglen L, Van Maldergem L, Piard J, Aftimos S, Mancini G, Dias P, Philip N, Goldenberg A, Le Merrer M, Rio M, Josifova D, Van Hagen JM, Lacombe D, Edery P, Dupuis-Girod S, Putoux A, Sanlaville D, Fischer R, Drévillon L, Briand-Suleau A, Metay C, Goossens M, Amiel J, Jacquette A, Giurgea I.

Hum Mutat. 2012 Jan;33(1):64-72. doi: 10.1002/humu.21639. Epub 2011 Nov 23.

PMID:
22045651
19.

Expression analysis of the genes identified in GWAS of the postmortem brain tissues from patients with schizophrenia.

Umeda-Yano S, Hashimoto R, Yamamori H, Weickert CS, Yasuda Y, Ohi K, Fujimoto M, Ito A, Takeda M.

Neurosci Lett. 2014 May 7;568:12-6. doi: 10.1016/j.neulet.2014.03.031. Epub 2014 Mar 28.

PMID:
24686180
20.

Zac1 regulates cell cycle arrest in neuronal progenitors via Tcf4.

Schmidt-Edelkraut U, Daniel G, Hoffmann A, Spengler D.

Mol Cell Biol. 2014 Mar;34(6):1020-30. doi: 10.1128/MCB.01195-13. Epub 2014 Jan 6.

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