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Items: 1 to 20 of 204

1.

Inhibition of vascular endothelial growth factor receptor under hypoxia causes severe, human-like pulmonary arterial hypertension in mice: potential roles of interleukin-6 and endothelin.

Van Hung T, Emoto N, Vignon-Zellweger N, Nakayama K, Yagi K, Suzuki Y, Hirata K.

Life Sci. 2014 Nov 24;118(2):313-28. doi: 10.1016/j.lfs.2013.12.215.

2.

Severe pulmonary arterial hypertension induced by SU5416 and ovalbumin immunization.

Mizuno S, Farkas L, Al Husseini A, Farkas D, Gomez-Arroyo J, Kraskauskas D, Nicolls MR, Cool CD, Bogaard HJ, Voelkel NF.

Am J Respir Cell Mol Biol. 2012 Nov;47(5):679-87. doi: 10.1165/rcmb.2012-0077OC.

PMID:
22842496
3.

Effects of vascular endothelial growth factor on endothelin-1 production by human lung microvascular endothelial cells in vitro.

Star GP, Giovinazzo M, Lamoureux E, Langleben D.

Life Sci. 2014 Nov 24;118(2):191-4. doi: 10.1016/j.lfs.2014.02.032.

4.

A novel murine model of severe pulmonary arterial hypertension.

Ciuclan L, Bonneau O, Hussey M, Duggan N, Holmes AM, Good R, Stringer R, Jones P, Morrell NW, Jarai G, Walker C, Westwick J, Thomas M.

Am J Respir Crit Care Med. 2011 Nov 15;184(10):1171-82. doi: 10.1164/rccm.201103-0412OC.

PMID:
21868504
5.

Endothelial Krüppel-like factor 4 modulates pulmonary arterial hypertension.

Shatat MA, Tian H, Zhang R, Tandon G, Hale A, Fritz JS, Zhou G, Martínez-González J, Rodríguez C, Champion HC, Jain MK, Hamik A.

Am J Respir Cell Mol Biol. 2014 Mar;50(3):647-53. doi: 10.1165/rcmb.2013-0135OC.

6.

Peroxisome Proliferator-Activated Receptor γ and microRNA 98 in Hypoxia-Induced Endothelin-1 Signaling.

Kang BY, Park KK, Kleinhenz JM, Murphy TC, Green DE, Bijli KM, Yeligar SM, Carthan KA, Searles CD, Sutliff RL, Hart CM.

Am J Respir Cell Mol Biol. 2016 Jan;54(1):136-46. doi: 10.1165/rcmb.2014-0337OC.

7.

Interleukin-6 overexpression induces pulmonary hypertension.

Steiner MK, Syrkina OL, Kolliputi N, Mark EJ, Hales CA, Waxman AB.

Circ Res. 2009 Jan 30;104(2):236-44, 28p following 244. doi: 10.1161/CIRCRESAHA.108.182014.

8.

Targeted activation of endothelin-1 exacerbates hypoxia-induced pulmonary hypertension.

Satwiko MG, Ikeda K, Nakayama K, Yagi K, Hocher B, Hirata K, Emoto N.

Biochem Biophys Res Commun. 2015 Sep 25;465(3):356-62. doi: 10.1016/j.bbrc.2015.08.002.

PMID:
26275708
10.

The effects of antiangiogenic compound SU5416 in a rat model of pulmonary arterial hypertension.

Sakao S, Tatsumi K.

Respiration. 2011;81(3):253-61. doi: 10.1159/000322011. Review.

PMID:
21116108
11.

Aldosterone inactivates the endothelin-B receptor via a cysteinyl thiol redox switch to decrease pulmonary endothelial nitric oxide levels and modulate pulmonary arterial hypertension.

Maron BA, Zhang YY, White K, Chan SY, Handy DE, Mahoney CE, Loscalzo J, Leopold JA.

Circulation. 2012 Aug 21;126(8):963-74. doi: 10.1161/CIRCULATIONAHA.112.094722.

12.
13.

Targeted delivery of pulmonary arterial endothelial cells overexpressing interleukin-8 receptors attenuates monocrotaline-induced pulmonary vascular remodeling.

Fu J, Chen YF, Zhao X, Creighton JR, Guo Y, Hage FG, Oparil S, Xing DD.

Arterioscler Thromb Vasc Biol. 2014 Jul;34(7):1539-47. doi: 10.1161/ATVBAHA.114.303821.

14.

Correlation between congenital heart disease complicated with pulmonary artery hypertension and circulating endothelial cells as well as endothelin-1.

Li X, Qiu J, Pan M, Zheng D, Su Y, Wei M, Kong X, Sun W, Zhu J.

Int J Clin Exp Pathol. 2015 Sep 1;8(9):10743-51.

15.

Peptide-directed highly selective targeting of pulmonary arterial hypertension.

Urakami T, Järvinen TA, Toba M, Sawada J, Ambalavanan N, Mann D, McMurtry I, Oka M, Ruoslahti E, Komatsu M.

Am J Pathol. 2011 Jun;178(6):2489-95. doi: 10.1016/j.ajpath.2011.02.032.

16.

Endothelial progenitor cells in pulmonary arterial hypertension.

Diller GP, Thum T, Wilkins MR, Wharton J.

Trends Cardiovasc Med. 2010 Jan;20(1):22-9. doi: 10.1016/j.tcm.2010.03.003. Review.

PMID:
20685574
17.

Nuclear factor κB inhibition reduces lung vascular lumen obliteration in severe pulmonary hypertension in rats.

Farkas D, Alhussaini AA, Kraskauskas D, Kraskauskiene V, Cool CD, Nicolls MR, Natarajan R, Farkas L.

Am J Respir Cell Mol Biol. 2014 Sep;51(3):413-25. doi: 10.1165/rcmb.2013-0355OC.

18.

Transfection of human hepatocyte growth factor gene inhibits advancing pulmonary arterial hypertension induced by shunt flow in a rabbit model.

Liu R, Wu S, Cao G, Wang W, Liu K, Wu S.

Transplant Proc. 2013 Mar;45(2):705-12. doi: 10.1016/j.transproceed.2012.07.158.

PMID:
23498810
19.

Endothelial injury in a transforming growth factor β-dependent mouse model of scleroderma induces pulmonary arterial hypertension.

Derrett-Smith EC, Dooley A, Gilbane AJ, Trinder SL, Khan K, Baliga R, Holmes AM, Hobbs AJ, Abraham D, Denton CP.

Arthritis Rheum. 2013 Nov;65(11):2928-39. doi: 10.1002/art.38078.

20.

Inhibition of the VEGF receptor 2 combined with chronic hypoxia causes cell death-dependent pulmonary endothelial cell proliferation and severe pulmonary hypertension.

Taraseviciene-Stewart L, Kasahara Y, Alger L, Hirth P, Mc Mahon G, Waltenberger J, Voelkel NF, Tuder RM.

FASEB J. 2001 Feb;15(2):427-38.

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