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Items: 1 to 20 of 102

1.

Histidine decarboxylase deficiency causes tourette syndrome: parallel findings in humans and mice.

Baldan LC, Williams KA, Gallezot JD, Pogorelov V, Rapanelli M, Crowley M, Anderson GM, Loring E, Gorczyca R, Billingslea E, Wasylink S, Panza KE, Ercan-Sencicek AG, Krusong K, Leventhal BL, Ohtsu H, Bloch MH, Hughes ZA, Krystal JH, Mayes L, de Araujo I, Ding YS, State MW, Pittenger C.

Neuron. 2014 Jan 8;81(1):77-90. doi: 10.1016/j.neuron.2013.10.052. Erratum in: Neuron. 2014 Jun 4;82(5):1186-7.

2.

Dysregulated intracellular signaling in the striatum in a pathophysiologically grounded model of Tourette syndrome.

Rapanelli M, Frick LR, Pogorelov V, Ota KT, Abbasi E, Ohtsu H, Pittenger C.

Eur Neuropsychopharmacol. 2014 Dec;24(12):1896-906. doi: 10.1016/j.euroneuro.2014.10.007. Epub 2014 Nov 4.

3.

Histidine Decarboxylase Knockout Mice as a Model of the Pathophysiology of Tourette Syndrome and Related Conditions.

Pittenger C.

Handb Exp Pharmacol. 2017;241:189-215. doi: 10.1007/164_2016_127. Review.

4.

Histidine decarboxylase knockout mice, a genetic model of Tourette syndrome, show repetitive grooming after induced fear.

Xu M, Li L, Ohtsu H, Pittenger C.

Neurosci Lett. 2015 May 19;595:50-3. doi: 10.1016/j.neulet.2015.03.067. Epub 2015 Apr 1.

5.
6.

Similar striatal D2/D3 dopamine receptor availability in adults with Tourette syndrome compared with healthy controls: A [(11) C]-(+)-PHNO and [(11) C]raclopride positron emission tomography imaging study.

Abi-Jaoude E, Segura B, Obeso I, Cho SS, Houle S, Lang AE, Rusjan P, Sandor P, Strafella AP.

Hum Brain Mapp. 2015 Jul;36(7):2592-601. doi: 10.1002/hbm.22793. Epub 2015 Mar 18.

PMID:
25788222
7.

Mutation screening of the HDC gene in Chinese Han patients with Tourette syndrome.

Lei J, Deng X, Zhang J, Su L, Xu H, Liang H, Huang X, Song Z, Deng H.

Am J Med Genet B Neuropsychiatr Genet. 2012 Jan;159B(1):72-6. doi: 10.1002/ajmg.b.32003. Epub 2011 Nov 16.

PMID:
22095709
8.

Dopaminergic activity in Tourette syndrome and obsessive-compulsive disorder.

Denys D, de Vries F, Cath D, Figee M, Vulink N, Veltman DJ, van der Doef TF, Boellaard R, Westenberg H, van Balkom A, Lammertsma AA, van Berckel BN.

Eur Neuropsychopharmacol. 2013 Nov;23(11):1423-31. doi: 10.1016/j.euroneuro.2013.05.012. Epub 2013 Jul 19.

9.
10.

Changes in motoric, exploratory and emotional behaviours and neuronal acetylcholine content and 5-HT turnover in histidine decarboxylase-KO mice.

Dere E, De Souza-Silva MA, Spieler RE, Lin JS, Ohtsu H, Haas HL, Huston JP.

Eur J Neurosci. 2004 Aug;20(4):1051-8.

PMID:
15305873
11.

Histamine H3R receptor activation in the dorsal striatum triggers stereotypies in a mouse model of tic disorders.

Rapanelli M, Frick L, Pogorelov V, Ohtsu H, Bito H, Pittenger C.

Transl Psychiatry. 2017 Jan 24;7(1):e1013. doi: 10.1038/tp.2016.290.

13.

Age-dependent measures of anxiety and cognition in male histidine decarboxylase knockout (Hdc-/-) mice.

Acevedo SF, Ohtsu H, Benice TS, Rizk-Jackson A, Raber J.

Brain Res. 2006 Feb 3;1071(1):113-23. Epub 2006 Jan 17.

PMID:
16412995
14.

Investigation of a Possible Role for the Histidine Decarboxylase Gene in Tourette Syndrome in the Chinese Han Population: A Family-Based Study.

Dong H, Liu W, Liu M, Xu L, Li Q, Zhang R, Zhang X, Liu S.

PLoS One. 2016 Aug 16;11(8):e0160265. doi: 10.1371/journal.pone.0160265. eCollection 2016.

15.

Anxiety and cognition in female histidine decarboxylase knockout (Hdc(-/-)) mice.

Acevedo SF, Pfankuch T, Ohtsu H, Raber J.

Behav Brain Res. 2006 Mar 15;168(1):92-9. Epub 2005 Nov 28.

PMID:
16310870
16.

L-histidine decarboxylase and Tourette's syndrome.

Ercan-Sencicek AG, Stillman AA, Ghosh AK, Bilguvar K, O'Roak BJ, Mason CE, Abbott T, Gupta A, King RA, Pauls DL, Tischfield JA, Heiman GA, Singer HS, Gilbert DL, Hoekstra PJ, Morgan TM, Loring E, Yasuno K, Fernandez T, Sanders S, Louvi A, Cho JH, Mane S, Colangelo CM, Biederer T, Lifton RP, Gunel M, State MW.

N Engl J Med. 2010 May 20;362(20):1901-8. doi: 10.1056/NEJMoa0907006. Epub 2010 May 5.

17.

Histamine regulation of microglia: Gene-environment interaction in the regulation of central nervous system inflammation.

Frick L, Rapanelli M, Abbasi E, Ohtsu H, Pittenger C.

Brain Behav Immun. 2016 Oct;57:326-337. doi: 10.1016/j.bbi.2016.07.002. Epub 2016 Jul 2.

18.

Support of the histaminergic hypothesis in Tourette syndrome: association of the histamine decarboxylase gene in a large sample of families.

Karagiannidis I, Dehning S, Sandor P, Tarnok Z, Rizzo R, Wolanczyk T, Madruga-Garrido M, Hebebrand J, Nöthen MM, Lehmkuhl G, Farkas L, Nagy P, Szymanska U, Anastasiou Z, Stathias V, Androutsos C, Tsironi V, Koumoula A, Barta C, Zill P, Mir P, Müller N, Barr C, Paschou P.

J Med Genet. 2013 Nov;50(11):760-4. doi: 10.1136/jmedgenet-2013-101637. Epub 2013 Jul 3.

PMID:
23825391
19.

Histamine modulation of the basal ganglia circuitry in the development of pathological grooming.

Rapanelli M, Frick L, Bito H, Pittenger C.

Proc Natl Acad Sci U S A. 2017 Jun 20;114(25):6599-6604. doi: 10.1073/pnas.1704547114. Epub 2017 Jun 5.

20.

Extrastriatal dopaminergic dysfunction in tourette syndrome.

Steeves TD, Ko JH, Kideckel DM, Rusjan P, Houle S, Sandor P, Lang AE, Strafella AP.

Ann Neurol. 2010 Feb;67(2):170-81. doi: 10.1002/ana.21809.

PMID:
20225192

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