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Items: 1 to 20 of 107

1.

Does high-dose coenzyme Q10 improve oxidative damage and clinical outcomes in Parkinson's disease?

Seet RC, Lim EC, Tan JJ, Quek AM, Chow AW, Chong WL, Ng MP, Ong CN, Halliwell B.

Antioxid Redox Signal. 2014 Jul 10;21(2):211-7. doi: 10.1089/ars.2013.5801. Epub 2014 Feb 24.

PMID:
24410614
2.

A randomized clinical trial of high-dosage coenzyme Q10 in early Parkinson disease: no evidence of benefit.

Parkinson Study Group QE3 Investigators, Beal MF, Oakes D, Shoulson I, Henchcliffe C, Galpern WR, Haas R, Juncos JL, Nutt JG, Voss TS, Ravina B, Shults CM, Helles K, Snively V, Lew MF, Griebner B, Watts A, Gao S, Pourcher E, Bond L, Kompoliti K, Agarwal P, Sia C, Jog M, Cole L, Sultana M, Kurlan R, Richard I, Deeley C, Waters CH, Figueroa A, Arkun A, Brodsky M, Ondo WG, Hunter CB, Jimenez-Shahed J, Palao A, Miyasaki JM, So J, Tetrud J, Reys L, Smith K, Singer C, Blenke A, Russell DS, Cotto C, Friedman JH, Lannon M, Zhang L, Drasby E, Kumar R, Subramanian T, Ford DS, Grimes DA, Cote D, Conway J, Siderowf AD, Evatt ML, Sommerfeld B, Lieberman AN, Okun MS, Rodriguez RL, Merritt S, Swartz CL, Martin WR, King P, Stover N, Guthrie S, Watts RL, Ahmed A, Fernandez HH, Winters A, Mari Z, Dawson TM, Dunlop B, Feigin AS, Shannon B, Nirenberg MJ, Ogg M, Ellias SA, Thomas CA, Frei K, Bodis-Wollner I, Glazman S, Mayer T, Hauser RA, Pahwa R, Langhammer A, Ranawaya R, Derwent L, Sethi KD, Farrow B, Prakash R, Litvan I, Robinson A, Sahay A, Gartner M, Hinson VK, Markind S, Pelikan M, Perlmutter JS, Hartlein J, Molho E, Evans S, Adler CH, Duffy A, Lind M, Elmer L, Davis K, Spears J, Wilson S, Leehey MA, Hermanowicz N, Niswonger S, Shill HA, Obradov S, Rajput A, Cowper M, Lessig S, Song D, Fontaine D, Zadikoff C, Williams K, Blindauer KA, Bergholte J, Propsom CS, Stacy MA, Field J, Mihaila D, Chilton M, Uc EY, Sieren J, Simon DK, Kraics L, Silver A, Boyd JT, Hamill RW, Ingvoldstad C, Young J, Thomas K, Kostyk SK, Wojcieszek J, Pfeiffer RF, Panisset M, Beland M, Reich SG, Cines M, Zappala N, Rivest J, Zweig R, Lumina LP, Hilliard CL, Grill S, Kellermann M, Tuite P, Rolandelli S, Kang UJ, Young J, Rao J, Cook MM, Severt L, Boyar K.

JAMA Neurol. 2014 May;71(5):543-52. doi: 10.1001/jamaneurol.2014.131.

PMID:
24664227
3.

Randomized, double-blind, placebo-controlled pilot trial of reduced coenzyme Q10 for Parkinson's disease.

Yoritaka A, Kawajiri S, Yamamoto Y, Nakahara T, Ando M, Hashimoto K, Nagase M, Saito Y, Hattori N.

Parkinsonism Relat Disord. 2015 Aug;21(8):911-6. doi: 10.1016/j.parkreldis.2015.05.022. Epub 2015 May 29.

PMID:
26054881
4.

Coenzyme Q10 dose-escalation study in hemodialysis patients: safety, tolerability, and effect on oxidative stress.

Yeung CK, Billings FT 4th, Claessens AJ, Roshanravan B, Linke L, Sundell MB, Ahmad S, Shao B, Shen DD, Ikizler TA, Himmelfarb J.

BMC Nephrol. 2015 Nov 3;16:183. doi: 10.1186/s12882-015-0178-2.

5.

Coenzyme Q10 for Patients with Parkinson's Disease: A Systematic Review and Meta-Analysis.

Negida A, Menshawy A, El Ashal G, Elfouly Y, Hani Y, Hegazy Y, El Ghonimy S, Fouda S, Rashad Y.

CNS Neurol Disord Drug Targets. 2016;15(1):45-53. Review.

PMID:
26553164
6.

Effect of Coenzyme Q10 on Biomarkers of Oxidative Stress and Cardiac Function in Hemodialysis Patients: The CoQ10 Biomarker Trial.

Rivara MB, Yeung CK, Robinson-Cohen C, Phillips BR, Ruzinski J, Rock D, Linke L, Shen DD, Ikizler TA, Himmelfarb J.

Am J Kidney Dis. 2017 Mar;69(3):389-399. doi: 10.1053/j.ajkd.2016.08.041. Epub 2016 Dec 4.

PMID:
27927588
7.

Effects of coenzyme Q10 in early Parkinson disease: evidence of slowing of the functional decline.

Shults CW, Oakes D, Kieburtz K, Beal MF, Haas R, Plumb S, Juncos JL, Nutt J, Shoulson I, Carter J, Kompoliti K, Perlmutter JS, Reich S, Stern M, Watts RL, Kurlan R, Molho E, Harrison M, Lew M; Parkinson Study Group.

Arch Neurol. 2002 Oct;59(10):1541-50.

PMID:
12374491
8.

Comparison study of plasma coenzyme Q10 levels in healthy subjects supplemented with ubiquinol versus ubiquinone.

Langsjoen PH, Langsjoen AM.

Clin Pharmacol Drug Dev. 2014 Jan;3(1):13-7. doi: 10.1002/cpdd.73. Epub 2013 Oct 8.

PMID:
27128225
9.

Randomized, double-blind, placebo-controlled trial on symptomatic effects of coenzyme Q(10) in Parkinson disease.

Storch A, Jost WH, Vieregge P, Spiegel J, Greulich W, Durner J, Müller T, Kupsch A, Henningsen H, Oertel WH, Fuchs G, Kuhn W, Niklowitz P, Koch R, Herting B, Reichmann H; German Coenzyme Q(10) Study Group.

Arch Neurol. 2007 Jul;64(7):938-44. Epub 2007 May 14.

PMID:
17502459
10.

Pilot trial of high dosages of coenzyme Q10 in patients with Parkinson's disease.

Shults CW, Flint Beal M, Song D, Fontaine D.

Exp Neurol. 2004 Aug;188(2):491-4.

PMID:
15246848
11.

Enrichment of coenzyme Q10 in plasma and blood cells: defense against oxidative damage.

Niklowitz P, Sonnenschein A, Janetzky B, Andler W, Menke T.

Int J Biol Sci. 2007 Apr 5;3(4):257-62.

12.

The efficacy and safety of coenzyme Q10 in Parkinson's disease: a meta-analysis of randomized controlled trials.

Zhu ZG, Sun MX, Zhang WL, Wang WW, Jin YM, Xie CL.

Neurol Sci. 2017 Feb;38(2):215-224. doi: 10.1007/s10072-016-2757-9. Epub 2016 Nov 9. Review.

PMID:
27830343
13.

Increased oxidative stress and coenzyme Q10 deficiency in juvenile fibromyalgia: amelioration of hypercholesterolemia and fatigue by ubiquinol-10 supplementation.

Miyamae T, Seki M, Naga T, Uchino S, Asazuma H, Yoshida T, Iizuka Y, Kikuchi M, Imagawa T, Natsumeda Y, Yokota S, Yamamoto Y.

Redox Rep. 2013;18(1):12-9. doi: 10.1179/1351000212Y.0000000036.

PMID:
23394493
14.

Effect of dietary coenzyme Q10 as an antioxidant in human plasma.

Weber C, Jakobsen TS, Mortensen SA, Paulsen G, Hølmer G.

Mol Aspects Med. 1994;15 Suppl:s97-102.

PMID:
7752850
15.

[Coenzyme Q10 in Parkinson's disease. Symptomatic or neuroprotective effects?].

Storch A.

Nervenarzt. 2007 Dec;78(12):1378-82. Review. German.

PMID:
17508194
16.

Altered redox state of platelet coenzyme Q10 in Parkinson's disease.

Götz ME, Gerstner A, Harth R, Dirr A, Janetzky B, Kuhn W, Riederer P, Gerlach M.

J Neural Transm (Vienna). 2000;107(1):41-8.

PMID:
10809402
17.

Plasma coenzyme Q10 response to oral ingestion of coenzyme Q10 formulations.

Bhagavan HN, Chopra RK.

Mitochondrion. 2007 Jun;7 Suppl:S78-88. Epub 2007 Mar 27. Review.

PMID:
17482886
18.

Coenzyme Q10 improves seminal oxidative defense but does not affect on semen parameters in idiopathic oligoasthenoteratozoospermia: a randomized double-blind, placebo controlled trial.

Nadjarzadeh A, Sadeghi MR, Amirjannati N, Vafa MR, Motevalian SA, Gohari MR, Akhondi MA, Yavari P, Shidfar F.

J Endocrinol Invest. 2011 Sep;34(8):e224-8. doi: 10.3275/7572. Epub 2011 Mar 7.

PMID:
21399391
19.

Dose ranging and efficacy study of high-dose coenzyme Q10 formulations in Huntington's disease mice.

Smith KM, Matson S, Matson WR, Cormier K, Del Signore SJ, Hagerty SW, Stack EC, Ryu H, Ferrante RJ.

Biochim Biophys Acta. 2006 Jun;1762(6):616-26. Epub 2006 Apr 17.

20.

Neuroprotection of Coenzyme Q10 in Neurodegenerative Diseases.

Yang X, Zhang Y, Xu H, Luo X, Yu J, Liu J, Chang RC.

Curr Top Med Chem. 2016;16(8):858-66. Review.

PMID:
26311425

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