Format
Sort by
Items per page

Send to

Choose Destination

Links from PubMed

Items: 1 to 20 of 131

1.

Multiple hereditary exostoses (MHE): elucidating the pathogenesis of a rare skeletal disorder through interdisciplinary research.

Jones KB, Pacifici M, Hilton MJ.

Connect Tissue Res. 2014 Apr;55(2):80-8. doi: 10.3109/03008207.2013.867957. Epub 2014 Feb 12.

PMID:
24409815
2.

Advances in the pathogenesis and possible treatments for multiple hereditary exostoses from the 2016 international MHE conference.

Phan AQ, Pacifici M, Esko JD.

Connect Tissue Res. 2018 Jan;59(1):85-98. doi: 10.1080/03008207.2017.1394295. Epub 2017 Nov 3.

PMID:
29099240
3.

A mouse model of chondrocyte-specific somatic mutation reveals a role for Ext1 loss of heterozygosity in multiple hereditary exostoses.

Matsumoto K, Irie F, Mackem S, Yamaguchi Y.

Proc Natl Acad Sci U S A. 2010 Jun 15;107(24):10932-7. doi: 10.1073/pnas.0914642107. Epub 2010 Jun 1.

4.

Heparan sulfate in skeletal development, growth, and pathology: the case of hereditary multiple exostoses.

Huegel J, Sgariglia F, Enomoto-Iwamoto M, Koyama E, Dormans JP, Pacifici M.

Dev Dyn. 2013 Sep;242(9):1021-32. doi: 10.1002/dvdy.24010. Epub 2013 Jul 29. Review.

5.

Multiple osteochondromas.

Bovée JV.

Orphanet J Rare Dis. 2008 Feb 13;3:3. doi: 10.1186/1750-1172-3-3. Review.

6.

Hereditary Multiple Exostoses: New Insights into Pathogenesis, Clinical Complications, and Potential Treatments.

Pacifici M.

Curr Osteoporos Rep. 2017 Jun;15(3):142-152. doi: 10.1007/s11914-017-0355-2. Review.

7.

Genotype-phenotype correlation in hereditary multiple exostoses.

Francannet C, Cohen-Tanugi A, Le Merrer M, Munnich A, Bonaventure J, Legeai-Mallet L.

J Med Genet. 2001 Jul;38(7):430-4.

8.

Cell biology of osteochondromas: bone morphogenic protein signalling and heparan sulphates.

Cuellar A, Reddi AH.

Int Orthop. 2013 Aug;37(8):1591-6. doi: 10.1007/s00264-013-1906-5. Epub 2013 Jun 15. Review.

9.

HSPG-deficient zebrafish uncovers dental aspect of multiple osteochondromas.

Wiweger MI, Zhao Z, van Merkesteyn RJ, Roehl HH, Hogendoorn PC.

PLoS One. 2012;7(1):e29734. doi: 10.1371/journal.pone.0029734. Epub 2012 Jan 11.

10.

Decreased EXT expression and intracellular accumulation of heparan sulphate proteoglycan in osteochondromas and peripheral chondrosarcomas.

Hameetman L, David G, Yavas A, White SJ, Taminiau AH, Cleton-Jansen AM, Hogendoorn PC, Bovée JV.

J Pathol. 2007 Mar;211(4):399-409.

PMID:
17226760
11.

Shop talk: Sugars, bones, and a disease called multiple hereditary exostoses.

Roehl HH, Pacifici M.

Dev Dyn. 2010 Jun;239(6):1901-4. doi: 10.1002/dvdy.22290.

12.

Similar cytogenetic findings in two synchronous secondary peripheral chondrosarcomas in a patient with multiple osteochondromas.

Kyriazoglou AI, Dimitriadis E, Arnogiannaki N, Brandal P, Heim S, Pandis N.

Cancer Genet. 2011 Dec;204(12):677-81. doi: 10.1016/j.cancergen.2011.10.013.

PMID:
22285020
13.

Hereditary Multiple Exostoses: a review of clinical appearance and metabolic pattern.

Beltrami G, Ristori G, Scoccianti G, Tamburini A, Capanna R.

Clin Cases Miner Bone Metab. 2016 May-Aug;13(2):110-118. Epub 2016 Oct 5. Review.

14.
15.

Unsuspected osteochondroma-like outgrowths in the cranial base of Hereditary Multiple Exostoses patients and modeling and treatment with a BMP antagonist in mice.

Sinha S, Mundy C, Bechtold T, Sgariglia F, Ibrahim MM, Billings PC, Carroll K, Koyama E, Jones KB, Pacifici M.

PLoS Genet. 2017 Apr 26;13(4):e1006742. doi: 10.1371/journal.pgen.1006742. eCollection 2017 Apr.

16.

Secondary peripheral chondrosarcoma evolving from osteochondroma as a result of outgrowth of cells with functional EXT.

de Andrea CE, Reijnders CM, Kroon HM, de Jong D, Hogendoorn PC, Szuhai K, Bovée JV.

Oncogene. 2012 Mar 1;31(9):1095-104. doi: 10.1038/onc.2011.311. Epub 2011 Aug 1.

PMID:
21804604
17.

Compound heterozygous loss of Ext1 and Ext2 is sufficient for formation of multiple exostoses in mouse ribs and long bones.

Zak BM, Schuksz M, Koyama E, Mundy C, Wells DE, Yamaguchi Y, Pacifici M, Esko JD.

Bone. 2011 May 1;48(5):979-87. doi: 10.1016/j.bone.2011.02.001. Epub 2011 Feb 15.

18.

[From gene to disease; hereditary multiple exostoses].

Wuyts W, Bovée JV, Hogendoorn PC.

Ned Tijdschr Geneeskd. 2002 Jan 26;146(4):162-4. Review. Dutch.

PMID:
11845565
19.

The neoplastic pathogenesis of solitary and multiple osteochondromas.

Porter DE, Simpson AH.

J Pathol. 1999 Jun;188(2):119-25. Review.

PMID:
10398153
20.

Molecular basis of multiple exostoses: mutations in the EXT1 and EXT2 genes.

Wuyts W, Van Hul W.

Hum Mutat. 2000;15(3):220-7. Review.

PMID:
10679937

Supplemental Content

Support Center