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Items: 1 to 20 of 73

1.

Functional genomic screen identifies novel mediators of collagen uptake.

Lee TH, McKleroy W, Khalifeh-Soltani A, Sakuma S, Lazarev S, Riento K, Nishimura SL, Nichols BJ, Atabai K.

Mol Biol Cell. 2014 Mar;25(5):583-93. doi: 10.1091/mbc.E13-07-0382. Epub 2014 Jan 8.

2.

The non-phagocytic route of collagen uptake: a distinct degradation pathway.

Madsen DH, Ingvarsen S, Jürgensen HJ, Melander MC, Kjøller L, Moyer A, Honoré C, Madsen CA, Garred P, Burgdorf S, Bugge TH, Behrendt N, Engelholm LH.

J Biol Chem. 2011 Jul 29;286(30):26996-7010. doi: 10.1074/jbc.M110.208033. Epub 2011 Jun 7.

3.

Intracellular collagen degradation mediated by uPARAP/Endo180 is a major pathway of extracellular matrix turnover during malignancy.

Curino AC, Engelholm LH, Yamada SS, Holmbeck K, Lund LR, Molinolo AA, Behrendt N, Nielsen BS, Bugge TH.

J Cell Biol. 2005 Jun 20;169(6):977-85.

4.

Endocytic collagen degradation: a novel mechanism involved in protection against liver fibrosis.

Madsen DH, Jürgensen HJ, Ingvarsen S, Melander MC, Vainer B, Egerod KL, Hald A, Rønø B, Madsen CA, Bugge TH, Engelholm LH, Behrendt N.

J Pathol. 2012 May;227(1):94-105. doi: 10.1002/path.3981. Epub 2012 Feb 17.

PMID:
22294280
5.

Genome-wide RNAi screen identifies SEC61A and VCP as conserved regulators of Sindbis virus entry.

Panda D, Rose PP, Hanna SL, Gold B, Hopkins KC, Lyde RB, Marks MS, Cherry S.

Cell Rep. 2013 Dec 26;5(6):1737-48. doi: 10.1016/j.celrep.2013.11.028. Epub 2013 Dec 12.

6.

uPARAP/Endo180 is essential for cellular uptake of collagen and promotes fibroblast collagen adhesion.

Engelholm LH, List K, Netzel-Arnett S, Cukierman E, Mitola DJ, Aaronson H, Kjøller L, Larsen JK, Yamada KM, Strickland DK, Holmbeck K, Danø K, Birkedal-Hansen H, Behrendt N, Bugge TH.

J Cell Biol. 2003 Mar 31;160(7):1009-15.

7.

The collagen receptor uPARAP/Endo180 in tissue degradation and cancer (Review).

Melander MC, Jürgensen HJ, Madsen DH, Engelholm LH, Behrendt N.

Int J Oncol. 2015 Oct;47(4):1177-88. doi: 10.3892/ijo.2015.3120. Epub 2015 Aug 12. Review.

8.

Complex determinants in specific members of the mannose receptor family govern collagen endocytosis.

Jürgensen HJ, Johansson K, Madsen DH, Porse A, Melander MC, Sørensen KR, Nielsen C, Bugge TH, Behrendt N, Engelholm LH.

J Biol Chem. 2014 Mar 14;289(11):7935-47. doi: 10.1074/jbc.M113.512780. Epub 2014 Feb 5.

9.

Extracellular collagenases and the endocytic receptor, urokinase plasminogen activator receptor-associated protein/Endo180, cooperate in fibroblast-mediated collagen degradation.

Madsen DH, Engelholm LH, Ingvarsen S, Hillig T, Wagenaar-Miller RA, Kjøller L, Gårdsvoll H, Høyer-Hansen G, Holmbeck K, Bugge TH, Behrendt N.

J Biol Chem. 2007 Sep 14;282(37):27037-45. Epub 2007 Jul 9.

10.

uPARAP/endo180 directs lysosomal delivery and degradation of collagen IV.

Kjøller L, Engelholm LH, Høyer-Hansen M, Danø K, Bugge TH, Behrendt N.

Exp Cell Res. 2004 Feb 1;293(1):106-16.

PMID:
14729061
11.

A novel functional role of collagen glycosylation: interaction with the endocytic collagen receptor uparap/ENDO180.

Jürgensen HJ, Madsen DH, Ingvarsen S, Melander MC, Gårdsvoll H, Patthy L, Engelholm LH, Behrendt N.

J Biol Chem. 2011 Sep 16;286(37):32736-48. doi: 10.1074/jbc.M111.266692. Epub 2011 Jul 18.

12.

Eater, a transmembrane protein mediating phagocytosis of bacterial pathogens in Drosophila.

Kocks C, Cho JH, Nehme N, Ulvila J, Pearson AM, Meister M, Strom C, Conto SL, Hetru C, Stuart LM, Stehle T, Hoffmann JA, Reichhart JM, Ferrandon D, Rämet M, Ezekowitz RA.

Cell. 2005 Oct 21;123(2):335-46.

13.

A genome-wide RNA interference screen identifies two novel components of the metazoan secretory pathway.

Wendler F, Gillingham AK, Sinka R, Rosa-Ferreira C, Gordon DE, Franch-Marro X, Peden AA, Vincent JP, Munro S.

EMBO J. 2010 Jan 20;29(2):304-14. doi: 10.1038/emboj.2009.350. Epub 2009 Nov 26.

14.

M2-like macrophages are responsible for collagen degradation through a mannose receptor-mediated pathway.

Madsen DH, Leonard D, Masedunskas A, Moyer A, Jürgensen HJ, Peters DE, Amornphimoltham P, Selvaraj A, Yamada SS, Brenner DA, Burgdorf S, Engelholm LH, Behrendt N, Holmbeck K, Weigert R, Bugge TH.

J Cell Biol. 2013 Sep 16;202(6):951-66. doi: 10.1083/jcb.201301081. Epub 2013 Sep 9.

15.

A network of conserved damage survival pathways revealed by a genomic RNAi screen.

Ravi D, Wiles AM, Bhavani S, Ruan J, Leder P, Bishop AJ.

PLoS Genet. 2009 Jun;5(6):e1000527. doi: 10.1371/journal.pgen.1000527. Epub 2009 Jun 19. Erratum in: PLoS Genet. 2009 Oct;5(10). doi: 10.1371/annotation/526db6e9-0ba5-4ec6-a257-2befb76f34b7.

16.

Reliance of Wolbachia on High Rates of Host Proteolysis Revealed by a Genome-Wide RNAi Screen of Drosophila Cells.

White PM, Serbus LR, Debec A, Codina A, Bray W, Guichet A, Lokey RS, Sullivan W.

Genetics. 2017 Apr;205(4):1473-1488. doi: 10.1534/genetics.116.198903. Epub 2017 Feb 3.

PMID:
28159754
17.

Always cleave up your mess: targeting collagen degradation to treat tissue fibrosis.

McKleroy W, Lee TH, Atabai K.

Am J Physiol Lung Cell Mol Physiol. 2013 Jun 1;304(11):L709-21. doi: 10.1152/ajplung.00418.2012. Epub 2013 Apr 5. Review.

18.

Phagocytosis of Collagen Fibrils by Fibroblasts In Vivo Is Independent of the uPARAP/Endo180 Receptor.

Sprangers S, Behrendt N, Engelholm L, Cao Y, Everts V.

J Cell Biochem. 2017 Jun;118(6):1590-1595. doi: 10.1002/jcb.25821. Epub 2017 Jan 11.

PMID:
27922193
19.

[Tissue-specific genome-wide RNAi screen in Drosophila].

Yamazaki M.

Tanpakushitsu Kakusan Koso. 2010 Jan;55(1):26-33. Review. Japanese. No abstract available.

PMID:
20058703
20.

Gain-of-function screen identifies a role of the Sec61alpha translocon in Drosophila postmitotic neurotoxicity.

Kanuka H, Hiratou T, Igaki T, Kanda H, Kuranaga E, Sawamoto K, Aigaki T, Okano H, Miura M.

Biochim Biophys Acta. 2005 Nov 30;1726(3):225-37. Epub 2005 Sep 27.

PMID:
16243437

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