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Items: 1 to 20 of 284

1.

Mitochondrial fragmentation is an important cellular event induced by ruthenium(II) polypyridyl complexes in osteosarcoma cells.

Du Y, Fu X, Li H, Chen B, Guo Y, Su G, Zhang H, Ning F, Lin Y, Mei W, Chen T.

ChemMedChem. 2014 Apr;9(4):714-8. doi: 10.1002/cmdc.201300379. Epub 2014 Jan 8.

PMID:
24403015
2.

Ruthenium(II) polypyridyl complexes: cellular uptake, cell image and apoptosis of HeLa cancer cells induced by double targets.

Yu Q, Liu Y, Xu L, Zheng C, Le F, Qin X, Liu Y, Liu J.

Eur J Med Chem. 2014 Jul 23;82:82-95. doi: 10.1016/j.ejmech.2014.05.040. Epub 2014 May 16.

PMID:
24878637
3.

Ruthenium(II) polypyridyl complexes induce BEL-7402 cell apoptosis by ROS-mediated mitochondrial pathway.

Jiang GB, Zheng X, Yao JH, Han BJ, Li W, Wang J, Huang HL, Liu YJ.

J Inorg Biochem. 2014 Dec;141:170-179. doi: 10.1016/j.jinorgbio.2014.09.001. Epub 2014 Sep 16.

PMID:
25268891
4.

Mixed-ligand ruthenium polypyridyl complexes as apoptosis inducers in cancer cells, the cellular translocation and the important role of ROS-mediated signaling.

Zhao Z, Luo Z, Wu Q, Zheng W, Feng Y, Chen T.

Dalton Trans. 2014 Dec 7;43(45):17017-28. doi: 10.1039/c4dt01392a.

PMID:
25087850
5.

A novel ruthenium(II)-polypyridyl complex inhibits cell proliferation and induces cell apoptosis by impairing DNA damage repair.

Yang Q, Zhang Z, Mei W, Sun F.

J Chemother. 2014 Aug;26(4):235-42. doi: 10.1179/1973947813Y.0000000138. Epub 2013 Dec 6.

PMID:
24070188
6.

Synthesis, characterization, and anticancer activity of ruthenium(II)-β-carboline complex.

Chen Y, Qin MY, Wu JH, Wang L, Chao H, Ji LN, Xu AL.

Eur J Med Chem. 2013;70:120-9. doi: 10.1016/j.ejmech.2013.09.051. Epub 2013 Oct 7.

PMID:
24141202
7.

Synthesis, characterization and anticancer activity studies of ruthenium(II) polypyridyl complexes on A549 cells.

Zeng CC, Jiang GB, Lai SH, Zhang C, Yin H, Tang B, Wan D, Liu YJ.

J Photochem Photobiol B. 2016 Aug;161:295-303. doi: 10.1016/j.jphotobiol.2016.06.004. Epub 2016 Jun 5.

PMID:
27288660
8.

Influence of carboxylic acid functionalities in ruthenium (II) polypyridyl complexes on DNA binding, cytotoxicity and antioxidant activity: synthesis, structure and in vitro anticancer activity.

Sathiya Kamatchi T, Chitrapriya N, Kim SK, Fronczek FR, Natarajan K.

Eur J Med Chem. 2013 Jan;59:253-64. doi: 10.1016/j.ejmech.2012.11.024. Epub 2012 Nov 27.

PMID:
23234855
9.

Synthesis, characterization, DNA interaction, antioxidant and anticancer activity studies of ruthenium(II) polypyridyl complexes.

Jiang GB, Xie YY, Lin GJ, Huang HL, Liang ZH, Liu YJ.

J Photochem Photobiol B. 2013 Dec 5;129:48-56. doi: 10.1016/j.jphotobiol.2013.09.009. Epub 2013 Oct 15.

PMID:
24177204
10.

Nuclear permeable ruthenium(II) β-carboline complexes induce autophagy to antagonize mitochondrial-mediated apoptosis.

Tan C, Lai S, Wu S, Hu S, Zhou L, Chen Y, Wang M, Zhu Y, Lian W, Peng W, Ji L, Xu A.

J Med Chem. 2010 Nov 11;53(21):7613-24. doi: 10.1021/jm1009296.

PMID:
20958054
11.

Ruthenium (II) polypyridyl complexes stabilize the bcl-2 promoter quadruplex and induce apoptosis of Hela tumor cells.

Wang C, Yu Q, Yang L, Liu Y, Sun D, Huang Y, Zhou Y, Zhang Q, Liu J.

Biometals. 2013 Jun;26(3):387-402. doi: 10.1007/s10534-013-9622-6. Epub 2013 Mar 30.

PMID:
23543383
12.

Ruthenium methylimidazole complexes induced apoptosis in lung cancer A549 cells through intrinsic mitochondrial pathway.

Yang X, Chen L, Liu Y, Yang Y, Chen T, Zheng W, Liu J, He QY.

Biochimie. 2012 Feb;94(2):345-53. doi: 10.1016/j.biochi.2011.07.025. Epub 2011 Jul 28.

PMID:
21816206
13.

Ruthenium polypyridyl complexes as inducer of ROS-mediated apoptosis in cancer cells by targeting thioredoxin reductase.

Luo Z, Yu L, Yang F, Zhao Z, Yu B, Lai H, Wong KH, Ngai SM, Zheng W, Chen T.

Metallomics. 2014 Aug;6(8):1480-90. doi: 10.1039/c4mt00044g.

PMID:
24823440
14.

Synthesis, Characterization, and in Vitro Antitumor Activity of Ruthenium(II) Polypyridyl Complexes Tethering EGFR-Inhibiting 4-Anilinoquinazolines.

Du J, Kang Y, Zhao Y, Zheng W, Zhang Y, Lin Y, Wang Z, Wang Y, Luo Q, Wu K, Wang F.

Inorg Chem. 2016 May 2;55(9):4595-605. doi: 10.1021/acs.inorgchem.6b00309. Epub 2016 Apr 19.

PMID:
27093574
15.

Synthesis and anticancer properties of ruthenium (II) complexes as potent apoptosis inducers through mitochondrial disruption.

Wan D, Tang B, Wang YJ, Guo BH, Yin H, Yi QY, Liu YJ.

Eur J Med Chem. 2017 Oct 20;139:180-190. doi: 10.1016/j.ejmech.2017.07.066. Epub 2017 Jul 28.

PMID:
28800456
16.

Arene-ruthenium(II) acylpyrazolonato complexes: apoptosis-promoting effects on human cancer cells.

Pettinari R, Pettinari C, Marchetti F, Skelton BW, White AH, Bonfili L, Cuccioloni M, Mozzicafreddo M, Cecarini V, Angeletti M, Nabissi M, Eleuteri AM.

J Med Chem. 2014 Jun 12;57(11):4532-42. doi: 10.1021/jm500458c. Epub 2014 May 20.

PMID:
24793593
17.

Synthesis, characterization; DNA binding and antitumor activity of ruthenium(II) polypyridyl complexes.

Srishailam A, Gabra NM, Kumar YP, Reddy KL, Devi CS, Anil Kumar D, Singh SS, Satyanarayana S.

J Photochem Photobiol B. 2014 Dec;141:47-58. doi: 10.1016/j.jphotobiol.2014.09.003. Epub 2014 Sep 16.

PMID:
25318017
18.

Biological Potential of Halfsandwich Ruthenium(II) and Iridium (III) Complexes.

Ludwig G, Mojić M, Bulatović M, Mijatović S, Maksimović-Ivanić D, Steinborn D, Kaluđerović GN.

Anticancer Agents Med Chem. 2016;16(11):1455-1460.

PMID:
26510901
19.

The induction of apoptosis in HepG-2 cells by ruthenium(II) complexes through an intrinsic ROS-mediated mitochondrial dysfunction pathway.

Zeng CC, Lai SH, Yao JH, Zhang C, Yin H, Li W, Han BJ, Liu YJ.

Eur J Med Chem. 2016 Oct 21;122:118-126. doi: 10.1016/j.ejmech.2016.06.020. Epub 2016 Jun 15.

PMID:
27344489
20.

Mitochondria are the primary target in the induction of apoptosis by chiral ruthenium(II) polypyridyl complexes in cancer cells.

Wang JQ, Zhang PY, Qian C, Hou XJ, Ji LN, Chao H.

J Biol Inorg Chem. 2014 Mar;19(3):335-48. doi: 10.1007/s00775-013-1069-2. Epub 2013 Nov 28.

PMID:
24287874

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