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Items: 1 to 20 of 193


Defining the ligand specificity of the deleted in colorectal cancer (DCC) receptor.

Haddick PC, Tom I, Luis E, Quiñones G, Wranik BJ, Ramani SR, Stephan JP, Tessier-Lavigne M, Gonzalez LC.

PLoS One. 2014 Jan 6;9(1):e84823. doi: 10.1371/journal.pone.0084823. eCollection 2014.


A signaling mechanism coupling netrin-1/deleted in colorectal cancer chemoattraction to SNARE-mediated exocytosis in axonal growth cones.

Cotrufo T, Pérez-Brangulí F, Muhaisen A, Ros O, Andrés R, Baeriswyl T, Fuschini G, Tarrago T, Pascual M, Ureña J, Blasi J, Giralt E, Stoeckli ET, Soriano E.

J Neurosci. 2011 Oct 12;31(41):14463-80. doi: 10.1523/JNEUROSCI.3018-11.2011.


p120RasGAP Protein Mediates Netrin-1 Protein-induced Cortical Axon Outgrowth and Guidance.

Antoine-Bertrand J, Duquette PM, Alchini R, Kennedy TE, Fournier AE, Lamarche-Vane N.

J Biol Chem. 2016 Feb 26;291(9):4589-602. doi: 10.1074/jbc.M115.674846. Epub 2015 Dec 28.


Direct binding of TUBB3 with DCC couples netrin-1 signaling to intracellular microtubule dynamics in axon outgrowth and guidance.

Qu C, Dwyer T, Shao Q, Yang T, Huang H, Liu G.

J Cell Sci. 2013 Jul 15;126(Pt 14):3070-81. doi: 10.1242/jcs.122184. Epub 2013 May 2.


The activation of ezrin-radixin-moesin proteins is regulated by netrin-1 through Src kinase and RhoA/Rho kinase activities and mediates netrin-1-induced axon outgrowth.

Antoine-Bertrand J, Ghogha A, Luangrath V, Bedford FK, Lamarche-Vane N.

Mol Biol Cell. 2011 Oct;22(19):3734-46. doi: 10.1091/mbc.E10-11-0917. Epub 2011 Aug 17.


Netrin-3, a mouse homolog of human NTN2L, is highly expressed in sensory ganglia and shows differential binding to netrin receptors.

Wang H, Copeland NG, Gilbert DJ, Jenkins NA, Tessier-Lavigne M.

J Neurosci. 1999 Jun 15;19(12):4938-47.


Binding of DCC by netrin-1 to mediate axon guidance independent of adenosine A2B receptor activation.

Stein E, Zou Y, Poo M, Tessier-Lavigne M.

Science. 2001 Mar 9;291(5510):1976-82.


Depolarization recruits DCC to the plasma membrane of embryonic cortical neurons and enhances axon extension in response to netrin-1.

Bouchard JF, Horn KE, Stroh T, Kennedy TE.

J Neurochem. 2008 Oct;107(2):398-417. doi: 10.1111/j.1471-4159.2008.05609.x. Epub 2008 Sep 18.


Netrin-1/DCC signaling in commissural axon guidance requires cell-autonomous expression of heparan sulfate.

Matsumoto Y, Irie F, Inatani M, Tessier-Lavigne M, Yamaguchi Y.

J Neurosci. 2007 Apr 18;27(16):4342-50.


Molecular guidance cues necessary for axon pathfinding from the ventral cochlear nucleus.

Howell DM, Morgan WJ, Jarjour AA, Spirou GA, Berrebi AS, Kennedy TE, Mathers PH.

J Comp Neurol. 2007 Oct 10;504(5):533-49.


The netrin 1 receptors Unc5h3 and Dcc are necessary at multiple choice points for the guidance of corticospinal tract axons.

Finger JH, Bronson RT, Harris B, Johnson K, Przyborski SA, Ackerman SL.

J Neurosci. 2002 Dec 1;22(23):10346-56.


Netrin1-DCC-Mediated Attraction Guides Post-Crossing Commissural Axons in the Hindbrain.

Shoja-Taheri F, DeMarco A, Mastick GS.

J Neurosci. 2015 Aug 19;35(33):11707-18. doi: 10.1523/JNEUROSCI.0613-15.2015.


Coordinated interaction of Down syndrome cell adhesion molecule and deleted in colorectal cancer with dynamic TUBB3 mediates Netrin-1-induced axon branching.

Huang H, Shao Q, Qu C, Yang T, Dwyer T, Liu G.

Neuroscience. 2015 May 7;293:109-22. doi: 10.1016/j.neuroscience.2015.02.042. Epub 2015 Mar 6.


Rho inhibition recruits DCC to the neuronal plasma membrane and enhances axon chemoattraction to netrin 1.

Moore SW, Correia JP, Lai Wing Sun K, Pool M, Fournier AE, Kennedy TE.

Development. 2008 Sep;135(17):2855-64. doi: 10.1242/dev.024133. Epub 2008 Jul 24.


Mapping netrin receptor binding reveals domains of Unc5 regulating its tyrosine phosphorylation.

Kruger RP, Lee J, Li W, Guan KL.

J Neurosci. 2004 Dec 1;24(48):10826-34.


Netrin-1-mediated axon guidance in mouse embryonic stem cells overexpressing neurogenin-1.

Hill GW 3rd, Purcell EK, Liu L, Velkey JM, Altschuler RA, Duncan RK.

Stem Cells Dev. 2012 Oct 10;21(15):2827-37. doi: 10.1089/scd.2011.0437. Epub 2012 Jun 4.


Tyrosine phosphorylation of the Rho guanine nucleotide exchange factor Trio regulates netrin-1/DCC-mediated cortical axon outgrowth.

DeGeer J, Boudeau J, Schmidt S, Bedford F, Lamarche-Vane N, Debant A.

Mol Cell Biol. 2013 Feb;33(4):739-51. doi: 10.1128/MCB.01264-12. Epub 2012 Dec 10.


c-Jun N-terminal kinase 1 (JNK1) is required for coordination of netrin signaling in axon guidance.

Qu C, Li W, Shao Q, Dwyer T, Huang H, Yang T, Liu G.

J Biol Chem. 2013 Jan 18;288(3):1883-95. doi: 10.1074/jbc.M112.417881. Epub 2012 Dec 6.


Signaling mechanism of the netrin-1 receptor DCC in axon guidance.

Finci L, Zhang Y, Meijers R, Wang JH.

Prog Biophys Mol Biol. 2015 Sep;118(3):153-60. doi: 10.1016/j.pbiomolbio.2015.04.001. Epub 2015 Apr 14. Review.


Draxin inhibits axonal outgrowth through the netrin receptor DCC.

Ahmed G, Shinmyo Y, Ohta K, Islam SM, Hossain M, Naser IB, Riyadh MA, Su Y, Zhang S, Tessier-Lavigne M, Tanaka H.

J Neurosci. 2011 Sep 28;31(39):14018-23. doi: 10.1523/JNEUROSCI.0943-11.2011.

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