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Items: 1 to 20 of 188

1.

Properties of 3-methyl-TIQ and 3-methyl-N-propargyl-TIQ for preventing MPTP-induced parkinsonism-like symptoms in mice.

Saitoh K, Abe K, Chiba T, Katagiri N, Saitoh T, Horiguchi Y, Nojima H, Taguchi K.

Pharmacol Rep. 2013;65(5):1204-12.

2.

Stereoselective effect of (R)- and (S)-1-methyl-1,2,3,4-tetrahydroisoquinolines on a mouse model of Parkinson's disease.

Abe K, Taguchi K, Wasai T, Ren J, Utsunomiya I, Shinohara T, Miyatake T, Sano T.

Brain Res Bull. 2001 Sep 1;56(1):55-60.

PMID:
11604249
3.

Preventative effects of 1,3-dimethyl- and 1,3-dimethyl-N-propargyl-1,2,3,4-tetrahydroisoquinoline on MPTP-induced Parkinson's disease-like symptoms in mice.

Katagiri N, Chida S, Abe K, Nojima H, Kitabatake M, Hoshi K, Horiguchi Y, Taguchi K.

Brain Res. 2010 Mar 19;1321:133-42. doi: 10.1016/j.brainres.2010.01.049. Epub 2010 Jan 28.

PMID:
20114039
5.

Effects of 1-cyclohexyl- and 1-cyclohexyl-N-propargyl-1,2,3,4-tetrahydroisoquinoline on dopaminergic spontaneous discharge in nigral neurons of rats.

Abe M, Munakata H, Abe K, Saito T, Horiguchi Y, Nojima H, Taguchi K.

Brain Res Bull. 2016 Mar;121:201-8. doi: 10.1016/j.brainresbull.2016.02.007. Epub 2016 Feb 10.

PMID:
26876935
7.

Effects of 1,2,3,4-tetrahydroisoquinoline derivatives on dopaminergic spontaneous discharge in substantia nigra neurons in rats.

Chiba H, Sato H, Abe K, Saito T, Horiguchi Y, Nojima H, Taguchi K.

Pharmacology. 2015;95(1-2):87-94. doi: 10.1159/000371580. Epub 2015 Jan 28.

PMID:
25633935
8.
9.

Synthesis of chiral 3-methyl- and 3-methyl-N-propargyl-1,2,3,4-tetrahydroisoquinoline and prevention of MPP+ -induced cytotoxicity.

Saitoh T, Yamashita A, Abe K, Ogawa K, Kitabatake M, Taguchi K, Horiguchi Y.

Med Chem. 2008 Nov;4(6):531-8.

PMID:
18991736
10.

EGb761 protects against nigrostriatal dopaminergic neurotoxicity in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced Parkinsonism in mice: role of oxidative stress.

Rojas P, Serrano-García N, Mares-Sámano JJ, Medina-Campos ON, Pedraza-Chaverri J, Ogren SO.

Eur J Neurosci. 2008 Jul;28(1):41-50. doi: 10.1111/j.1460-9568.2008.06314.x.

PMID:
18662333
11.

Biochemical and pathological study of endogenous 1-benzyl-1,2,3,4-tetrahydroisoquinoline-induced parkinsonism in the mouse.

Abe K, Taguchi K, Wasai T, Ren J, Utsunomiya I, Shinohara T, Miyatake T, Sano T.

Brain Res. 2001 Jul 13;907(1-2):134-8.

PMID:
11430895
12.

Neuroprotection in Parkinson models varies with toxin administration protocol.

Anderson DW, Bradbury KA, Schneider JS.

Eur J Neurosci. 2006 Dec;24(11):3174-82.

PMID:
17156378
13.

Tripchlorolide protects against MPTP-induced neurotoxicity in C57BL/6 mice.

Hong Z, Wang G, Gu J, Pan J, Bai L, Zhang S, Chen SD.

Eur J Neurosci. 2007 Sep;26(6):1500-8. Epub 2007 Aug 20.

PMID:
17714494
14.
15.

Melatonin enhances L-DOPA therapeutic effects, helps to reduce its dose, and protects dopaminergic neurons in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced Parkinsonism in mice.

Naskar A, Prabhakar V, Singh R, Dutta D, Mohanakumar KP.

J Pineal Res. 2015 Apr;58(3):262-74. doi: 10.1111/jpi.12212. Epub 2015 Feb 23.

PMID:
25626558
16.
17.

Pharmacokinetic, neurochemical, stereological and neuropathological studies on the potential effects of paraquat in the substantia nigra pars compacta and striatum of male C57BL/6J mice.

Breckenridge CB, Sturgess NC, Butt M, Wolf JC, Zadory D, Beck M, Mathews JM, Tisdel MO, Minnema D, Travis KZ, Cook AR, Botham PA, Smith LL.

Neurotoxicology. 2013 Jul;37:1-14. doi: 10.1016/j.neuro.2013.03.005. Epub 2013 Mar 21.

18.

The potentiating effects of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) on paraquat-induced neurochemical and behavioral changes in mice.

Shepherd KR, Lee ES, Schmued L, Jiao Y, Ali SF, Oriaku ET, Lamango NS, Soliman KF, Charlton CG.

Pharmacol Biochem Behav. 2006 Mar;83(3):349-59. Epub 2006 Mar 6.

PMID:
16580056
19.

Ropinirole protects against 1-methyl-4-phenyl-1, 2, 3, 6-tetrahydropyridine (MPTP)-induced neurotoxicity in mice via anti-apoptotic mechanism.

Park G, Park YJ, Yang HO, Oh MS.

Pharmacol Biochem Behav. 2013 Mar;104:163-8. doi: 10.1016/j.pbb.2013.01.017. Epub 2013 Jan 28.

PMID:
23369986
20.

Social enrichment attenuates nigrostriatal lesioning and reverses motor impairment in a progressive 1-methyl-2-phenyl-1,2,3,6-tetrahydropyridine (MPTP) mouse model of Parkinson's disease.

Goldberg NR, Fields V, Pflibsen L, Salvatore MF, Meshul CK.

Neurobiol Dis. 2012 Mar;45(3):1051-67. doi: 10.1016/j.nbd.2011.12.024. Epub 2011 Dec 14.

PMID:
22198503

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