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Items: 1 to 20 of 97

1.

Glycogen Synthase Kinase 3 Inactivation Induces Cell Senescence through Sterol Regulatory Element Binding Protein 1-Mediated Lipogenesis in Chang Cells.

Kim YM, Song I, Seo YH, Yoon G.

Endocrinol Metab (Seoul). 2013 Dec;28(4):297-308. doi: 10.3803/EnM.2013.28.4.297. Epub 2013 Dec 12.

2.

Sterol regulatory element-binding protein (SREBP)-1-mediated lipogenesis is involved in cell senescence.

Kim YM, Shin HT, Seo YH, Byun HO, Yoon SH, Lee IK, Hyun DH, Chung HY, Yoon G.

J Biol Chem. 2010 Sep 17;285(38):29069-77. doi: 10.1074/jbc.M110.120386. Epub 2010 Jul 8.

3.
4.

Roles of GSK3 in metabolic shift toward abnormal anabolism in cell senescence.

Kim YM, Seo YH, Park CB, Yoon SH, Yoon G.

Ann N Y Acad Sci. 2010 Jul;1201:65-71. doi: 10.1111/j.1749-6632.2010.05617.x. Review.

PMID:
20649541
5.

Enhanced glycogenesis is involved in cellular senescence via GSK3/GS modulation.

Seo YH, Jung HJ, Shin HT, Kim YM, Yim H, Chung HY, Lim IK, Yoon G.

Aging Cell. 2008 Dec;7(6):894-907. doi: 10.1111/j.1474-9726.2008.00436.x. Epub 2008 Sep 8.

6.

PKR-like endoplasmic reticulum kinase is necessary for lipogenic activation during HCMV infection.

Yu Y, Pierciey FJ Jr, Maguire TG, Alwine JC.

PLoS Pathog. 2013;9(4):e1003266. doi: 10.1371/journal.ppat.1003266. Epub 2013 Apr 4.

7.

PKCδ phosphorylation is an upstream event of GSK3 inactivation-mediated ROS generation in TGF-β1-induced senescence.

Byun HO, Jung HJ, Kim MJ, Yoon G.

Free Radic Res. 2014 Sep;48(9):1100-8. doi: 10.3109/10715762.2014.929120. Epub 2014 Jul 21.

PMID:
24917460
8.

GSK3 inactivation is involved in mitochondrial complex IV defect in transforming growth factor (TGF) β1-induced senescence.

Byun HO, Jung HJ, Seo YH, Lee YK, Hwang SC, Hwang ES, Yoon G.

Exp Cell Res. 2012 Sep 10;318(15):1808-19. doi: 10.1016/j.yexcr.2012.04.012. Epub 2012 May 28.

PMID:
22652454
9.

Human cytomegalovirus infection induces adipocyte-like lipogenesis through activation of sterol regulatory element binding protein 1.

Yu Y, Maguire TG, Alwine JC.

J Virol. 2012 Mar;86(6):2942-9. doi: 10.1128/JVI.06467-11. Epub 2012 Jan 18.

10.

Obesity-related overexpression of fatty-acid synthase gene in adipose tissue involves sterol regulatory element-binding protein transcription factors.

Boizard M, Le Liepvre X, Lemarchand P, Foufelle F, Ferré P, Dugail I.

J Biol Chem. 1998 Oct 30;273(44):29164-71.

11.

Increased lipogenesis, induced by AKT-mTORC1-RPS6 signaling, promotes development of human hepatocellular carcinoma.

Calvisi DF, Wang C, Ho C, Ladu S, Lee SA, Mattu S, Destefanis G, Delogu S, Zimmermann A, Ericsson J, Brozzetti S, Staniscia T, Chen X, Dombrowski F, Evert M.

Gastroenterology. 2011 Mar;140(3):1071-83. doi: 10.1053/j.gastro.2010.12.006. Epub 2010 Dec 11.

12.

The effect of feed restriction on expression of hepatic lipogenic genes in broiler chickens and the function of SREBP1.

Wang PH, Ko YH, Chin HJ, Hsu C, Ding ST, Chen CY.

Comp Biochem Physiol B Biochem Mol Biol. 2009 Aug;153(4):327-31. doi: 10.1016/j.cbpb.2009.04.003. Epub 2009 Apr 19.

PMID:
19383549
13.

Pregnane X receptor activation and silencing promote steatosis of human hepatic cells by distinct lipogenic mechanisms.

Bitter A, Rümmele P, Klein K, Kandel BA, Rieger JK, Nüssler AK, Zanger UM, Trauner M, Schwab M, Burk O.

Arch Toxicol. 2015 Nov;89(11):2089-103. doi: 10.1007/s00204-014-1348-x. Epub 2014 Sep 3.

PMID:
25182422
14.

Regulation of lipid synthesis by liver X receptor α and sterol regulatory element-binding protein 1 in mammary epithelial cells.

Oppi-Williams C, Suagee JK, Corl BA.

J Dairy Sci. 2013 Jan;96(1):112-21. doi: 10.3168/jds.2011-5276. Epub 2012 Oct 24.

PMID:
23102957
15.

Betulinic acid alleviates non-alcoholic fatty liver by inhibiting SREBP1 activity via the AMPK-mTOR-SREBP signaling pathway.

Quan HY, Kim DY, Kim SJ, Jo HK, Kim GW, Chung SH.

Biochem Pharmacol. 2013 May 1;85(9):1330-40. doi: 10.1016/j.bcp.2013.02.007. Epub 2013 Feb 19.

PMID:
23435355
16.

Human sterol regulatory element-binding protein 1a contributes significantly to hepatic lipogenic gene expression.

Bitter A, Nüssler AK, Thasler WE, Klein K, Zanger UM, Schwab M, Burk O.

Cell Physiol Biochem. 2015;35(2):803-15. doi: 10.1159/000369739. Epub 2015 Jan 30.

17.

Overexpression of SREBP1 (sterol regulatory element binding protein 1) promotes de novo fatty acid synthesis and triacylglycerol accumulation in goat mammary epithelial cells.

Xu HF, Luo J, Zhao WS, Yang YC, Tian HB, Shi HB, Bionaz M.

J Dairy Sci. 2016 Jan;99(1):783-95. doi: 10.3168/jds.2015-9736. Epub 2015 Nov 18.

PMID:
26601584
18.

SREBP1 regulates tumorigenesis and prognosis of pancreatic cancer through targeting lipid metabolism.

Sun Y, He W, Luo M, Zhou Y, Chang G, Ren W, Wu K, Li X, Shen J, Zhao X, Hu Y.

Tumour Biol. 2015 Jun;36(6):4133-41. doi: 10.1007/s13277-015-3047-5. Epub 2015 Jan 15.

PMID:
25589463
19.

cAMP response element binding protein H mediates fenofibrate-induced suppression of hepatic lipogenesis.

Min AK, Jeong JY, Go Y, Choi YK, Kim YD, Lee IK, Park KG.

Diabetologia. 2013 Feb;56(2):412-22. doi: 10.1007/s00125-012-2771-2. Epub 2012 Nov 13.

PMID:
23150180
20.

Activated α2-macroglobulin binding to human prostate cancer cells triggers insulin-like responses.

Misra UK, Pizzo SV.

J Biol Chem. 2015 Apr 10;290(15):9571-87. doi: 10.1074/jbc.M114.617837. Epub 2015 Feb 26.

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