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Items: 1 to 20 of 96

1.

Regulation of interferon gamma signaling by suppressors of cytokine signaling and regulatory T cells.

Larkin J 3rd, Ahmed CM, Wilson TD, Johnson HM.

Front Immunol. 2013 Dec 18;4:469. doi: 10.3389/fimmu.2013.00469. Erratum in: Front Immunol. 2014;5(5):88.

2.

Inhibition of SOCS1-/- lethal autoinflammatory disease correlated to enhanced peripheral Foxp3+ regulatory T cell homeostasis.

Collins EL, Jager LD, Dabelic R, Benitez P, Holdstein K, Lau K, Haider MI, Johnson HM, Larkin J 3rd.

J Immunol. 2011 Sep 1;187(5):2666-76. doi: 10.4049/jimmunol.1003819. Epub 2011 Jul 25.

3.

Loss of suppressor of cytokine signaling 1 in helper T cells leads to defective Th17 differentiation by enhancing antagonistic effects of IFN-gamma on STAT3 and Smads.

Tanaka K, Ichiyama K, Hashimoto M, Yoshida H, Takimoto T, Takaesu G, Torisu T, Hanada T, Yasukawa H, Fukuyama S, Inoue H, Nakanishi Y, Kobayashi T, Yoshimura A.

J Immunol. 2008 Mar 15;180(6):3746-56.

4.

Suppressor of cytokine signaling-1 regulates inflammatory bowel disease in which both IFNgamma and IL-4 are involved.

Chinen T, Kobayashi T, Ogata H, Takaesu G, Takaki H, Hashimoto M, Yagita H, Nawata H, Yoshimura A.

Gastroenterology. 2006 Feb;130(2):373-88.

PMID:
16472593
5.

SOCS1 is essential for regulatory T cell functions by preventing loss of Foxp3 expression as well as IFN-{gamma} and IL-17A production.

Takahashi R, Nishimoto S, Muto G, Sekiya T, Tamiya T, Kimura A, Morita R, Asakawa M, Chinen T, Yoshimura A.

J Exp Med. 2011 Sep 26;208(10):2055-67. doi: 10.1084/jem.20110428. Epub 2011 Sep 5.

6.

Suppressor of cytokine signalling 1 (SOCS1) is a physiological regulator of the asthma response.

Lee C, Kolesnik TB, Caminschi I, Chakravorty A, Carter W, Alexander WS, Jones J, Anderson GP, Nicholson SE.

Clin Exp Allergy. 2009 Jun;39(6):897-907. doi: 10.1111/j.1365-2222.2009.03217.x. Epub 2009 Mar 20.

7.

SOCS1 and regulation of regulatory T cells plasticity.

Takahashi R, Yoshimura A.

J Immunol Res. 2014;2014:943149. doi: 10.1155/2014/943149. Epub 2014 Jul 15. Review.

8.

Re-examination of the role of suppressor of cytokine signaling 1 (SOCS1) in the regulation of toll-like receptor signaling.

Gingras S, Parganas E, de Pauw A, Ihle JN, Murray PJ.

J Biol Chem. 2004 Dec 24;279(52):54702-7. Epub 2004 Oct 18.

9.

Expression of suppressor of cytokine signaling 1 (SOCS1) impairs viral clearance and exacerbates lung injury during influenza infection.

Sun K, Salmon S, Yajjala VK, Bauer C, Metzger DW.

PLoS Pathog. 2014 Dec 11;10(12):e1004560. doi: 10.1371/journal.ppat.1004560. eCollection 2014 Dec.

10.

IFNgamma-dependent, spontaneous development of colorectal carcinomas in SOCS1-deficient mice.

Hanada T, Kobayashi T, Chinen T, Saeki K, Takaki H, Koga K, Minoda Y, Sanada T, Yoshioka T, Mimata H, Kato S, Yoshimura A.

J Exp Med. 2006 Jun 12;203(6):1391-7. Epub 2006 May 22.

11.

Persistence of lesions in suppressor of cytokine signaling-1-deficient mice infected with Leishmania major.

Bullen DV, Baldwin TM, Curtis JM, Alexander WS, Handman E.

J Immunol. 2003 Apr 15;170(8):4267-72.

12.

Enhanced anti-tumor activity of interferon-alpha in SOCS1-deficient mice is mediated by CD4⁺ and CD8⁺ T cells.

Guenterberg KD, Lesinski GB, Mundy-Bosse BL, Karpa VI, Jaime-Ramirez AC, Wei L, Carson WE 3rd.

Cancer Immunol Immunother. 2011 Sep;60(9):1281-8. doi: 10.1007/s00262-011-1034-2. Epub 2011 May 21.

13.

SOCS1: Regulator of T Cells in Autoimmunity and Cancer.

Ilangumaran S, Bobbala D, Ramanathan S.

Curr Top Microbiol Immunol. 2017;410:159-189. doi: 10.1007/82_2017_63.

PMID:
28900678
15.

Increased nuclear suppressor of cytokine signaling 1 in asthmatic bronchial epithelium suppresses rhinovirus induction of innate interferons.

Gielen V, Sykes A, Zhu J, Chan B, Macintyre J, Regamey N, Kieninger E, Gupta A, Shoemark A, Bossley C, Davies J, Saglani S, Walker P, Nicholson SE, Dalpke AH, Kon OM, Bush A, Johnston SL, Edwards MR.

J Allergy Clin Immunol. 2015 Jul;136(1):177-188.e11. doi: 10.1016/j.jaci.2014.11.039. Epub 2015 Jan 25.

16.

Inhibition of microRNA let-7i depresses maturation and functional state of dendritic cells in response to lipopolysaccharide stimulation via targeting suppressor of cytokine signaling 1.

Zhang M, Liu F, Jia H, Zhang Q, Yin L, Liu W, Li H, Yu B, Wu J.

J Immunol. 2011 Aug 15;187(4):1674-83. doi: 10.4049/jimmunol.1001937. Epub 2011 Jul 8.

17.

The comparative roles of suppressor of cytokine signaling-1 and -3 in the inhibition and desensitization of cytokine signaling.

Wormald S, Zhang JG, Krebs DL, Mielke LA, Silver J, Alexander WS, Speed TP, Nicola NA, Hilton DJ.

J Biol Chem. 2006 Apr 21;281(16):11135-43. Epub 2006 Feb 10.

18.

SOCS1 is a critical inhibitor of interferon gamma signaling and prevents the potentially fatal neonatal actions of this cytokine.

Alexander WS, Starr R, Fenner JE, Scott CL, Handman E, Sprigg NS, Corbin JE, Cornish AL, Darwiche R, Owczarek CM, Kay TW, Nicola NA, Hertzog PJ, Metcalf D, Hilton DJ.

Cell. 1999 Sep 3;98(5):597-608.

19.

Suppressors of cytokine signaling-1 and -3 regulate osteoclastogenesis in the presence of inflammatory cytokines.

Ohishi M, Matsumura Y, Aki D, Mashima R, Taniguchi K, Kobayashi T, Kukita T, Iwamoto Y, Yoshimura A.

J Immunol. 2005 Mar 1;174(5):3024-31.

20.

Suppressor of cytokine signaling-1 in T cells and macrophages is critical for preventing lethal inflammation.

Chong MM, Metcalf D, Jamieson E, Alexander WS, Kay TW.

Blood. 2005 Sep 1;106(5):1668-75. Epub 2005 May 17.

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