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Items: 1 to 20 of 147

1.

EPO-dependent activation of PI3K/Akt/FoxO3a signalling mediates neuroprotection in in vitro and in vivo models of Parkinson's disease.

Jia Y, Mo SJ, Feng QQ, Zhan ML, OuYang LS, Chen JC, Ma YX, Wu JJ, Lei WL.

J Mol Neurosci. 2014 May;53(1):117-24. doi: 10.1007/s12031-013-0208-0. Epub 2014 Jan 4.

PMID:
24390959
2.

Involvement of PI3K/Akt/FoxO3a and PKA/CREB Signaling Pathways in the Protective Effect of Fluoxetine Against Corticosterone-Induced Cytotoxicity in PC12 Cells.

Zeng B, Li Y, Niu B, Wang X, Cheng Y, Zhou Z, You T, Liu Y, Wang H, Xu J.

J Mol Neurosci. 2016 Aug;59(4):567-78. doi: 10.1007/s12031-016-0779-7. Epub 2016 Jul 13.

PMID:
27412469
3.
4.

Neuroprotective effects of erythropoietin on 6-hydroxydopamine-treated ventral mesencephalic dopamine-rich cultures.

Ganser C, Papazoglou A, Just L, Nikkhah G.

Exp Cell Res. 2010 Mar 10;316(5):737-46. doi: 10.1016/j.yexcr.2010.01.001. Epub 2010 Jan 11.

PMID:
20060824
5.

7,8-dihydroxyflavone protects PC12 cells against 6-hydroxydopamine-induced cell death through modulating PI3K/Akt and JNK pathways.

Han XH, Cheng MN, Chen L, Fang H, Wang LJ, Li XT, Qu ZQ.

Neurosci Lett. 2014 Oct 3;581:85-8. doi: 10.1016/j.neulet.2014.08.016. Epub 2014 Aug 17.

PMID:
25139527
6.

Resveratrol protects PC12 cells from high glucose-induced neurotoxicity via PI3K/Akt/FoxO3a pathway.

Liu MH, Yuan C, He J, Tan TP, Wu SJ, Fu HY, Liu J, Yu S, Chen YD, Le QF, Tian W, Hu HJ, Zhang Y, Lin XL.

Cell Mol Neurobiol. 2015 May;35(4):513-22. doi: 10.1007/s10571-014-0147-5. Epub 2014 Dec 4.

PMID:
25471227
7.

Essential role for Stat5 in the neurotrophic but not in the neuroprotective effect of erythropoietin.

Byts N, Samoylenko A, Fasshauer T, Ivanisevic M, Hennighausen L, Ehrenreich H, Sirén AL.

Cell Death Differ. 2008 Apr;15(4):783-92. doi: 10.1038/cdd.2008.1. Epub 2008 Feb 8.

8.

Neuroprotective properties of icariin in MPTP-induced mouse model of Parkinson's disease: Involvement of PI3K/Akt and MEK/ERK signaling pathways.

Chen WF, Wu L, Du ZR, Chen L, Xu AL, Chen XH, Teng JJ, Wong MS.

Phytomedicine. 2017 Feb 15;25:93-99. doi: 10.1016/j.phymed.2016.12.017. Epub 2016 Dec 29.

PMID:
28190476
9.

Erythropoietin-mediated protection of insect brain neurons involves JAK and STAT but not PI3K transduction pathways.

Miljus N, Heibeck S, Jarrar M, Micke M, Ostrowski D, Ehrenreich H, Heinrich R.

Neuroscience. 2014 Jan 31;258:218-27. doi: 10.1016/j.neuroscience.2013.11.020. Epub 2013 Nov 21.

PMID:
24269933
10.

Erythropoietin protects PC12 cells from beta-amyloid(25-35)-induced apoptosis via PI3K/Akt signaling pathway.

Ma R, Xiong N, Huang C, Tang Q, Hu B, Xiang J, Li G.

Neuropharmacology. 2009 May-Jun;56(6-7):1027-34. doi: 10.1016/j.neuropharm.2009.02.006. Epub 2009 Mar 4.

PMID:
19268480
11.

Squamosamide derivative FLZ protected dopaminergic neuron by activating Akt signaling pathway in 6-OHDA-induced in vivo and in vitro Parkinson's disease models.

Bao XQ, Kong XC, Kong LB, Wu LY, Sun H, Zhang D.

Brain Res. 2014 Feb 14;1547:49-57. doi: 10.1016/j.brainres.2013.12.026. Epub 2013 Dec 30.

PMID:
24384139
12.

Activated phosphatidylinositol 3-kinase/Akt inhibits the transition of endothelial progenitor cells to mesenchymal cells by regulating the forkhead box subgroup O-3a signaling.

Zhang Z, Zhang T, Zhou Y, Wei X, Zhu J, Zhang J, Wang C.

Cell Physiol Biochem. 2015;35(4):1643-53. doi: 10.1159/000373978. Epub 2015 Mar 18.

13.

Danshensu protects against 6-hydroxydopamine-induced damage of PC12 cells in vitro and dopaminergic neurons in zebrafish.

Chong CM, Zhou ZY, Razmovski-Naumovski V, Cui GZ, Zhang LQ, Sa F, Hoi PM, Chan K, Lee SM.

Neurosci Lett. 2013 May 24;543:121-5. doi: 10.1016/j.neulet.2013.02.069. Epub 2013 Apr 3.

PMID:
23562886
14.

Guanosine protects glial cells against 6-hydroxydopamine toxicity.

Giuliani P, Ballerini P, Buccella S, Ciccarelli R, Rathbone MP, Romano S, D'Alimonte I, Caciagli F, Di Iorio P, Pokorski M.

Adv Exp Med Biol. 2015;837:23-33. doi: 10.1007/5584_2014_73.

PMID:
25310956
15.

Activation of the Akt/FKHRL1 pathway mediates the antiapoptotic effects of erythropoietin in primary human erythroid progenitors.

Uddin S, Kottegoda S, Stigger D, Platanias LC, Wickrema A.

Biochem Biophys Res Commun. 2000 Aug 18;275(1):16-9.

PMID:
10944433
16.

Puerarin protects differentiated PC12 cells from H₂O₂-induced apoptosis through the PI3K/Akt signalling pathway.

Zhang Q, Huang WD, Lv XY, Yang YM.

Cell Biol Int. 2012 May 1;36(5):419-26. doi: 10.1042/CBI20100900.

PMID:
22126839
17.

Troxerutin exerts neuroprotection in 6-hydroxydopamine lesion rat model of Parkinson's disease: Possible involvement of PI3K/ERβ signaling.

Baluchnejadmojarad T, Jamali-Raeufy N, Zabihnejad S, Rabiee N, Roghani M.

Eur J Pharmacol. 2017 Apr 15;801:72-78. doi: 10.1016/j.ejphar.2017.03.002. Epub 2017 Mar 8.

PMID:
28284752
18.

The role of Akt/FoxO3a in the protective effect of venlafaxine against corticosterone-induced cell death in PC12 cells.

Wang H, Zhou X, Huang J, Mu N, Guo Z, Wen Q, Wang R, Chen S, Feng ZP, Zheng W.

Psychopharmacology (Berl). 2013 Jul;228(1):129-41. doi: 10.1007/s00213-013-3017-9. Epub 2013 Mar 15.

PMID:
23494228
19.

Simvastatin induces neuroprotection in 6-OHDA-lesioned PC12 via the PI3K/AKT/caspase 3 pathway and anti-inflammatory responses.

Xu YQ, Long L, Yan JQ, Wei L, Pan MQ, Gao HM, Zhou P, Liu M, Zhu CS, Tang BS, Wang Q.

CNS Neurosci Ther. 2013 Mar;19(3):170-7. doi: 10.1111/cns.12053. Epub 2012 Dec 28.

PMID:
23279934
20.

Cell type-specific dependency on the PI3K/Akt signaling pathway for the endogenous Epo and VEGF induction by baicalein in neurons versus astrocytes.

Sun YY, Lin SH, Lin HC, Hung CC, Wang CY, Lin YC, Hung KS, Lien CC, Kuan CY, Lee YH.

PLoS One. 2013 Jul 19;8(7):e69019. doi: 10.1371/journal.pone.0069019. Print 2013.

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