Format
Sort by
Items per page

Send to

Choose Destination

Links from PubMed

Items: 1 to 20 of 130

1.

Integrin αvβ6 promotes an osteolytic program in cancer cells by upregulating MMP2.

Dutta A, Li J, Lu H, Akech J, Pratap J, Wang T, Zerlanko BJ, FitzGerald TJ, Jiang Z, Birbe R, Wixted J, Violette SM, Stein JL, Stein GS, Lian JB, Languino LR.

Cancer Res. 2014 Mar 1;74(5):1598-608. doi: 10.1158/0008-5472.CAN-13-1796. Epub 2014 Jan 2.

2.

αvβ6 integrin is required for TGFβ1-mediated matrix metalloproteinase2 expression.

Dutta A, Li J, Fedele C, Sayeed A, Singh A, Violette SM, Manes TD, Languino LR.

Biochem J. 2015 Mar 15;466(3):525-36. doi: 10.1042/BJ20140698.

3.

Matrix metalloproteinase (MMP)-13 regulates mammary tumor-induced osteolysis by activating MMP9 and transforming growth factor-beta signaling at the tumor-bone interface.

Nannuru KC, Futakuchi M, Varney ML, Vincent TM, Marcusson EG, Singh RK.

Cancer Res. 2010 May 1;70(9):3494-504. doi: 10.1158/0008-5472.CAN-09-3251. Epub 2010 Apr 20.

4.

Scutellarin inhibits the growth and invasion of human tongue squamous carcinoma through the inhibition of matrix metalloproteinase-2 and -9 and αvβ6 integrin.

Li H, Huang D, Gao Z, Chen Y, Zhang L, Zheng J.

Int J Oncol. 2013 May;42(5):1674-81. doi: 10.3892/ijo.2013.1873. Epub 2013 Mar 28.

PMID:
23546449
5.
6.

Altered microenvironment promotes progression of preinvasive breast cancer: myoepithelial expression of αvβ6 integrin in DCIS identifies high-risk patients and predicts recurrence.

Allen MD, Thomas GJ, Clark S, Dawoud MM, Vallath S, Payne SJ, Gomm JJ, Dreger SA, Dickinson S, Edwards DR, Pennington CJ, Sestak I, Cuzick J, Marshall JF, Hart IR, Jones JL.

Clin Cancer Res. 2014 Jan 15;20(2):344-57. doi: 10.1158/1078-0432.CCR-13-1504. Epub 2013 Oct 22.

7.

Immunolocalization of MMP9 and MMP2 in osteolytic metastasis originating from MDA-MB-231 human breast cancer cells.

Liu B, Cui J, Sun J, Li J, Han X, Guo J, Yi M, Amizuka N, Xu X, Li M.

Mol Med Rep. 2016 Aug;14(2):1099-106. doi: 10.3892/mmr.2016.5374. Epub 2016 Jun 7.

8.

The αvβ6 integrin is transferred intercellularly via exosomes.

Fedele C, Singh A, Zerlanko BJ, Iozzo RV, Languino LR.

J Biol Chem. 2015 Feb 20;290(8):4545-51. doi: 10.1074/jbc.C114.617662. Epub 2015 Jan 7.

9.

Induction of an epithelial integrin alphavbeta6 in human cytomegalovirus-infected endothelial cells leads to activation of transforming growth factor-beta1 and increased collagen production.

Tabata T, Kawakatsu H, Maidji E, Sakai T, Sakai K, Fang-Hoover J, Aiba M, Sheppard D, Pereira L.

Am J Pathol. 2008 Apr;172(4):1127-40. doi: 10.2353/ajpath.2008.070448. Epub 2008 Mar 18.

10.

Effect of Id1 knockdown on formation of osteolytic bone lesions by prostate cancer PC3 cells in vivo.

Zhang Z, Li K, Zhang X, Fang Z, Xiong W, Chen Q, Chen W, Li F.

J Huazhong Univ Sci Technolog Med Sci. 2012 Jun;32(3):364-9. doi: 10.1007/s11596-012-0063-1. Epub 2012 Jun 9.

PMID:
22684559
11.

A human monoclonal antibody 264RAD targeting αvβ6 integrin reduces tumour growth and metastasis, and modulates key biomarkers in vivo.

Eberlein C, Kendrew J, McDaid K, Alfred A, Kang JS, Jacobs VN, Ross SJ, Rooney C, Smith NR, Rinkenberger J, Cao A, Churchman A, Marshall JF, Weir HM, Bedian V, Blakey DC, Foltz IN, Barry ST.

Oncogene. 2013 Sep 12;32(37):4406-16. doi: 10.1038/onc.2012.460. Epub 2012 Oct 29.

PMID:
23108397
12.

Multiple cellular mechanisms related to cyclin A1 in prostate cancer invasion and metastasis.

Wegiel B, Bjartell A, Tuomela J, Dizeyi N, Tinzl M, Helczynski L, Nilsson E, Otterbein LE, Härkönen P, Persson JL.

J Natl Cancer Inst. 2008 Jul 16;100(14):1022-36. doi: 10.1093/jnci/djn214. Epub 2008 Jul 8.

13.

Discoidin domain receptor 2 facilitates prostate cancer bone metastasis via regulating parathyroid hormone-related protein.

Yan Z, Jin S, Wei Z, Huilian H, Zhanhai Y, Yue T, Juan L, Jing L, Libo Y, Xu L.

Biochim Biophys Acta. 2014 Sep;1842(9):1350-63. doi: 10.1016/j.bbadis.2014.04.018. Epub 2014 Apr 27.

14.

Suppression of Hedgehog signalling promotes pro-tumourigenic integrin expression and function.

Moutasim KA, Mellows T, Mellone M, Lopez MA, Tod J, Kiely PC, Sapienza K, Greco A, Neill GW, Violette S, Weinreb PH, Marshall JF, Ottensmeier CH, Sayan AE, Jenei V, Thomas GJ.

J Pathol. 2014 Jun;233(2):196-208. doi: 10.1002/path.4342. Epub 2014 Apr 29.

PMID:
24573955
15.
16.

Defining the role of integrin alphavbeta6 in cancer.

Bandyopadhyay A, Raghavan S.

Curr Drug Targets. 2009 Jul;10(7):645-52. Review.

17.

Pathogenic role of connective tissue growth factor (CTGF/CCN2) in osteolytic metastasis of breast cancer.

Shimo T, Kubota S, Yoshioka N, Ibaragi S, Isowa S, Eguchi T, Sasaki A, Takigawa M.

J Bone Miner Res. 2006 Jul;21(7):1045-59.

18.

Estrogens promote invasion of prostate cancer cells in a paracrine manner through up-regulation of matrix metalloproteinase 2 in prostatic stromal cells.

Yu L, Wang CY, Shi J, Miao L, Du X, Mayer D, Zhang J.

Endocrinology. 2011 Mar;152(3):773-81. doi: 10.1210/en.2010-1239. Epub 2011 Jan 19.

PMID:
21248144
19.

Matrix rigidity induces osteolytic gene expression of metastatic breast cancer cells.

Ruppender NS, Merkel AR, Martin TJ, Mundy GR, Sterling JA, Guelcher SA.

PLoS One. 2010 Nov 15;5(11):e15451. doi: 10.1371/journal.pone.0015451.

20.

Supplemental Content

Support Center