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Items: 1 to 20 of 195

1.

TGF-beta1-Induced MAPK activation promotes collagen synthesis, nodule formation, redox stress and cellular senescence in porcine aortic valve interstitial cells.

Das D, Holmes A, Murphy GA, Mishra K, Rosenkranz AC, Horowitz JD, Kennedy JA.

J Heart Valve Dis. 2013 Sep;22(5):621-30.

PMID:
24383372
2.

Inhibition of transforming growth factor (TGF)-beta1-induced extracellular matrix with a novel inhibitor of the TGF-beta type I receptor kinase activity: SB-431542.

Laping NJ, Grygielko E, Mathur A, Butter S, Bomberger J, Tweed C, Martin W, Fornwald J, Lehr R, Harling J, Gaster L, Callahan JF, Olson BA.

Mol Pharmacol. 2002 Jul;62(1):58-64.

3.
4.

Inhibition of calcifying nodule formation in cultured porcine aortic valve cells by nitric oxide donors.

Kennedy JA, Hua X, Mishra K, Murphy GA, Rosenkranz AC, Horowitz JD.

Eur J Pharmacol. 2009 Jan 5;602(1):28-35. doi: 10.1016/j.ejphar.2008.11.029. Epub 2008 Nov 27.

PMID:
19056377
5.

Smad2-dependent glycosaminoglycan elongation in aortic valve interstitial cells enhances binding of LDL to proteoglycans.

Osman N, Grande-Allen KJ, Ballinger ML, Getachew R, Marasco S, O'Brien KD, Little PJ.

Cardiovasc Pathol. 2013 Mar-Apr;22(2):146-55. doi: 10.1016/j.carpath.2012.07.002. Epub 2012 Sep 21.

PMID:
22999704
6.

Gefitinib attenuates transforming growth factor-β1-activated mitogen-activated protein kinases and mitogenesis in NRK-49F cells.

Chen SC, Guh JY, Lin TD, Chiou SJ, Hwang CC, Ko YM, Chuang LY.

Transl Res. 2011 Oct;158(4):214-24. doi: 10.1016/j.trsl.2011.06.002. Epub 2011 Jul 7.

PMID:
21925118
7.

Progression of aortic valve stenosis: TGF-beta1 is present in calcified aortic valve cusps and promotes aortic valve interstitial cell calcification via apoptosis.

Jian B, Narula N, Li QY, Mohler ER 3rd, Levy RJ.

Ann Thorac Surg. 2003 Feb;75(2):457-65; discussion 465-6.

PMID:
12607654
8.

Role of cross-talk between the Smad2 and MAPK pathways in TGF-beta1-induced collagen IV expression in mesangial cells.

Jiang W, Zhang Y, Wu H, Zhang X, Gan H, Sun J, Chen Q, Guo M, Zhang Z.

Int J Mol Med. 2010 Oct;26(4):571-6.

PMID:
20818498
9.
10.

Association between shear stress and platelet-derived transforming growth factor-β1 release and activation in animal models of aortic valve stenosis.

Wang W, Vootukuri S, Meyer A, Ahamed J, Coller BS.

Arterioscler Thromb Vasc Biol. 2014 Sep;34(9):1924-32. doi: 10.1161/ATVBAHA.114.303852. Epub 2014 Jun 5.

11.

Transforming growth factor-β1 impairs CFTR-mediated anion secretion across cultured porcine vas deferens epithelial monolayer via the p38 MAPK pathway.

Yi S, Pierucci-Alves F, Schultz BD.

Am J Physiol Cell Physiol. 2013 Oct 15;305(8):C867-76. doi: 10.1152/ajpcell.00121.2013. Epub 2013 Jul 31.

12.

Rosiglitazone inhibits transforming growth factor-β1 mediated fibrogenesis in ADPKD cyst-lining epithelial cells.

Liu Y, Dai B, Xu C, Fu L, Hua Z, Mei C.

PLoS One. 2011;6(12):e28915. doi: 10.1371/journal.pone.0028915. Epub 2011 Dec 9.

13.

Calcification by valve interstitial cells is regulated by the stiffness of the extracellular matrix.

Yip CY, Chen JH, Zhao R, Simmons CA.

Arterioscler Thromb Vasc Biol. 2009 Jun;29(6):936-42. doi: 10.1161/ATVBAHA.108.182394. Epub 2009 Mar 19.

14.

Transforming growth factor-beta1 regulates the fate of cultured spinal cord-derived neural progenitor cells.

Park SM, Jung JS, Jang MS, Kang KS, Kang SK.

Cell Prolif. 2008 Apr;41(2):248-64. doi: 10.1111/j.1365-2184.2008.00514.x. Erratum in: Cell Prolif. 2008 Oct;41(5):841.

PMID:
18336470
15.

Role of ALK5/Smad2/3 and MEK1/ERK Signaling in Transforming Growth Factor Beta 1-modulated Growth, Collagen Turnover, and Differentiation of Stem Cells from Apical Papilla of Human Tooth.

Chang HH, Chang MC, Wu IH, Huang GF, Huang WL, Wang YL, Lee SY, Yeh CY, Guo MK, Chan CP, Hsien HC, Jeng JH.

J Endod. 2015 Aug;41(8):1272-80. doi: 10.1016/j.joen.2015.03.022. Epub 2015 May 19.

PMID:
26001858
16.

Doxycycline inhibits TGF-beta1-induced MMP-9 via Smad and MAPK pathways in human corneal epithelial cells.

Kim HS, Luo L, Pflugfelder SC, Li DQ.

Invest Ophthalmol Vis Sci. 2005 Mar;46(3):840-8.

PMID:
15728539
17.

Transforming growth factor-beta1 induces apoptosis in vascular endothelial cells by activation of mitogen-activated protein kinase.

Hyman KM, Seghezzi G, Pintucci G, Stellari G, Kim JH, Grossi EA, Galloway AC, Mignatti P.

Surgery. 2002 Aug;132(2):173-9.

PMID:
12219008
18.

Release of leukotriene B4, transforming growth factor-beta1 and microparticles in relation to aortic valve calcification.

Kochtebane N, Passefort S, Choqueux C, Ainoun F, Achour L, Michel JB, Bäck M, Jacob MP.

J Heart Valve Dis. 2013 Nov;22(6):782-8.

PMID:
24597398
19.

Transforming growth factor-beta1 mechanisms in aortic valve calcification: increased alkaline phosphatase and related events.

Clark-Greuel JN, Connolly JM, Sorichillo E, Narula NR, Rapoport HS, Mohler ER 3rd, Gorman JH 3rd, Gorman RC, Levy RJ.

Ann Thorac Surg. 2007 Mar;83(3):946-53.

PMID:
17307438
20.

Activation of TLR3 induces osteogenic responses in human aortic valve interstitial cells through the NF-κB and ERK1/2 pathways.

Zhan Q, Song R, Zeng Q, Yao Q, Ao L, Xu D, Fullerton DA, Meng X.

Int J Biol Sci. 2015 Mar 20;11(4):482-93. doi: 10.7150/ijbs.10905. eCollection 2015.

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