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Items: 1 to 20 of 109

1.

NAD(P)H-independent asymmetric C=C bond reduction catalyzed by ene reductases by using artificial co-substrates as the hydrogen donor.

Winkler CK, Clay D, Entner M, Plank M, Faber K.

Chemistry. 2014 Jan 27;20(5):1403-9. doi: 10.1002/chem.201303897. Epub 2013 Dec 30.

2.

Overcoming co-product inhibition in the nicotinamide independent asymmetric bioreduction of activated C=C-bonds using flavin-dependent ene-reductases.

Winkler CK, Clay D, van Heerden E, Faber K.

Biotechnol Bioeng. 2013 Dec;110(12):3085-92. doi: 10.1002/bit.24981. Epub 2013 Jul 10.

3.

A highly efficient ADH-coupled NADH-recycling system for the asymmetric bioreduction of carbon-carbon double bonds using enoate reductases.

Tauber K, Hall M, Kroutil W, Fabian WM, Faber K, Glueck SM.

Biotechnol Bioeng. 2011 Jun;108(6):1462-7. doi: 10.1002/bit.23078. Epub 2011 Mar 1.

PMID:
21328323
4.

Asymmetric bioreduction of activated C=C bonds using enoate reductases from the old yellow enzyme family.

Stuermer R, Hauer B, Hall M, Faber K.

Curr Opin Chem Biol. 2007 Apr;11(2):203-13. Epub 2007 Mar 13. Review.

PMID:
17353140
5.
6.

A substrate-driven approach to determine reactivities of α,β-unsaturated carboxylic esters towards asymmetric bioreduction.

Tasnádi G, Winkler CK, Clay D, Sultana N, Fabian WM, Hall M, Ditrich K, Faber K.

Chemistry. 2012 Aug 13;18(33):10362-7. doi: 10.1002/chem.201200990. Epub 2012 Jun 26.

PMID:
22736443
7.

Stereocomplementary bioreduction of alpha,beta-unsaturated dicarboxylic acids and dimethyl esters using enoate reductases: enzyme- and substrate-based stereocontrol.

Stueckler C, Hall M, Ehammer H, Pointner E, Kroutil W, Macheroux P, Faber K.

Org Lett. 2007 Dec 20;9(26):5409-11. Epub 2007 Nov 22.

PMID:
18031047
8.

A hydrogen bond network in the active site of Anabaena ferredoxin-NADP(+) reductase modulates its catalytic efficiency.

Sánchez-Azqueta A, Herguedas B, Hurtado-Guerrero R, Hervás M, Navarro JA, Martínez-Júlvez M, Medina M.

Biochim Biophys Acta. 2014 Feb;1837(2):251-63. doi: 10.1016/j.bbabio.2013.10.010. Epub 2013 Nov 4.

9.

Recombinant S. cerevisiae expressing Old Yellow Enzymes from non-conventional yeasts: an easy system for selective reduction of activated alkenes.

Romano D, Contente ML, Molinari F, Eberini I, Ruvutuso E, Sensi C, Amaretti A, Rossi M, Raimondi S.

Microb Cell Fact. 2014 Apr 25;13:60. doi: 10.1186/1475-2859-13-60.

10.

Characterization of the mechanism of the NADH-dependent polysulfide reductase (Npsr) from Shewanella loihica PV-4: formation of a productive NADH-enzyme complex and its role in the general mechanism of NADH and FAD-dependent enzymes.

Lee KH, Humbarger S, Bahnvadia R, Sazinsky MH, Crane EJ 3rd.

Biochim Biophys Acta. 2014 Sep;1844(9):1708-17. doi: 10.1016/j.bbapap.2014.06.013. Epub 2014 Jun 26.

PMID:
24981797
11.
12.

The bioinspired construction of an ordered carbon nitride array for photocatalytic mediated enzymatic reduction.

Liu J, Cazelles R, Chen ZP, Zhou H, Galarneau A, Antonietti M.

Phys Chem Chem Phys. 2014 Jul 28;16(28):14699-705. doi: 10.1039/c4cp01348d.

PMID:
24915954
13.

A Rapid and High-Throughput Assay for the Estimation of Conversions of Ene-Reductase-Catalysed Reactions.

Forchin MC, Crotti M, Gatti FG, Parmeggiani F, Brenna E, Monti D.

Chembiochem. 2015 Jul 27;16(11):1571-3. doi: 10.1002/cbic.201500219. Epub 2015 Jun 24.

PMID:
26033160
14.

Chemoenzymatic asymmetric synthesis of pregabalin precursors via asymmetric bioreduction of β-cyanoacrylate esters using ene-reductases.

Winkler CK, Clay D, Davies S, O'Neill P, McDaid P, Debarge S, Steflik J, Karmilowicz M, Wong JW, Faber K.

J Org Chem. 2013 Feb 15;78(4):1525-33. doi: 10.1021/jo302484p. Epub 2013 Jan 28.

15.

Recent advances in the biocatalytic reduction of ketones and oxidation of sec-alcohols.

Kroutil W, Mang H, Edegger K, Faber K.

Curr Opin Chem Biol. 2004 Apr;8(2):120-6. Review.

PMID:
15062771
16.

Linking distinct conformations of nicotinamide adenine dinucleotide with protein fold/function.

Kuppuraj G, Sargsyan K, Hua YH, Merrill AR, Lim C.

J Phys Chem B. 2011 Jun 23;115(24):7932-9. doi: 10.1021/jp1118663. Epub 2011 May 25.

PMID:
21612228
18.

Comparative characterization of novel ene-reductases from cyanobacteria.

Fu Y, Castiglione K, Weuster-Botz D.

Biotechnol Bioeng. 2013 May;110(5):1293-301. doi: 10.1002/bit.24817. Epub 2013 Jan 21.

PMID:
23280373
19.

Asymmetric bioreduction of alkenes using ene-reductases YersER and KYE1 and effects of organic solvents.

Yanto Y, Winkler CK, Lohr S, Hall M, Faber K, Bommarius AS.

Org Lett. 2011 May 20;13(10):2540-3. doi: 10.1021/ol200394p. Epub 2011 Apr 21.

PMID:
21510626

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