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Functional heterogeneity of NADPH oxidase-mediated contractions to endothelin with vascular aging.

Meyer MR, Barton M, Prossnitz ER.

Life Sci. 2014 Nov 24;118(2):226-31. doi: 10.1016/j.lfs.2013.12.021.


Endothelin-1 but not angiotensin II contributes to functional aging in murine carotid arteries.

Meyer MR, Fredette NC, Barton M, Prossnitz ER.

Life Sci. 2014 Nov 24;118(2):213-8. doi: 10.1016/j.lfs.2014.02.027.


Marked heterogeneity of endothelin-mediated contractility and contraction dynamics in mouse renal and femoral arteries.

Widmer CC, Mundy AL, Kretz M, Barton M.

Exp Biol Med (Maywood). 2006 Jun;231(6):777-81.


Endothelin mediates superoxide production and vasoconstriction through activation of NADPH oxidase and uncoupled nitric-oxide synthase in the rat aorta.

Loomis ED, Sullivan JC, Osmond DA, Pollock DM, Pollock JS.

J Pharmacol Exp Ther. 2005 Dec;315(3):1058-64.


Prostanoid-mediated contractions of the carotid artery become Nox2-independent with aging.

Meyer MR, Fredette NC, Barton M, Prossnitz ER.

Age (Dordr). 2015 Aug;37(4):9806. doi: 10.1007/s11357-015-9806-9.


Voluntary wheel running restores endothelial function in conduit arteries of old mice: direct evidence for reduced oxidative stress, increased superoxide dismutase activity and down-regulation of NADPH oxidase.

Durrant JR, Seals DR, Connell ML, Russell MJ, Lawson BR, Folian BJ, Donato AJ, Lesniewski LA.

J Physiol. 2009 Jul 1;587(Pt 13):3271-85. doi: 10.1113/jphysiol.2009.169771.


Obesity and heterozygous endothelial overexpression of prepro-endothelin-1 modulate responsiveness of mouse main and segmental renal arteries to vasoconstrictor agents.

Baretella O, Chung SK, Barton M, Xu A, Vanhoutte PM.

Life Sci. 2014 Nov 24;118(2):206-12. doi: 10.1016/j.lfs.2013.12.214.


Intrarenal artery superoxide is mainly NADPH oxidase-derived and modulates endothelium-dependent dilation in elderly patients.

Schlüter T, Zimmermann U, Protzel C, Miehe B, Klebingat KJ, Rettig R, Grisk O.

Cardiovasc Res. 2010 Mar 1;85(4):814-24. doi: 10.1093/cvr/cvp346.


NADPH oxidase-derived superoxide augments endothelin-1-induced venoconstriction in mineralocorticoid hypertension.

Li L, Watts SW, Banes AK, Galligan JJ, Fink GD, Chen AF.

Hypertension. 2003 Sep;42(3):316-21.


Endothelin-1 impairs coronary arteriolar dilation: Role of p38 kinase-mediated superoxide production from NADPH oxidase.

Thengchaisri N, Hein TW, Ren Y, Kuo L.

J Mol Cell Cardiol. 2015 Sep;86:75-84. doi: 10.1016/j.yjmcc.2015.07.014.


Endothelial dysfunction in acute renal failure: role of circulating and tissue endothelin-1.

Ruschitzka F, Shaw S, Gygi D, Noll G, Barton M, Lüscher TF.

J Am Soc Nephrol. 1999 May;10(5):953-62.


Red wine polyphenols prevent endothelial dysfunction induced by endothelin-1 in rat aorta: role of NADPH oxidase.

López-Sepúlveda R, Gómez-Guzmán M, Zarzuelo MJ, Romero M, Sánchez M, Quintela AM, Galindo P, O'Valle F, Tamargo J, Pérez-Vizcaíno F, Duarte J, Jiménez R.

Clin Sci (Lond). 2011 Apr;120(8):321-33. doi: 10.1042/CS20100311.


Increased endothelial exocytosis and generation of endothelin-1 contributes to constriction of aged arteries.

Goel A, Su B, Flavahan S, Lowenstein CJ, Berkowitz DE, Flavahan NA.

Circ Res. 2010 Jul 23;107(2):242-51. doi: 10.1161/CIRCRESAHA.109.210229.


Endothelium-restricted overexpression of human endothelin-1 causes vascular remodeling and endothelial dysfunction.

Amiri F, Virdis A, Neves MF, Iglarz M, Seidah NG, Touyz RM, Reudelhuber TL, Schiffrin EL.

Circulation. 2004 Oct 12;110(15):2233-40.


Early aging and anatomic heterogeneity determine cyclooxygenase-mediated vasoconstriction to angiotensin II in mice.

Kretz M, Mundy AL, Widmer CC, Barton M.

J Cardiovasc Pharmacol. 2006 Aug;48(2):30-3.


NADPH-induced contractions of mouse aorta do not involve NADPH oxidase: a role for P2X receptors.

Judkins CP, Sobey CG, Dang TT, Miller AA, Dusting GJ, Drummond GR.

J Pharmacol Exp Ther. 2006 May;317(2):644-50.


Mechanisms underlying the contractile response to endothelin-1 in the rat renal artery.

Callera GE, Bendhack LM.

Pharmacology. 2003 Jul;68(3):131-9.


Toll-like receptor 4 mutation protects obese mice against endothelial dysfunction by decreasing NADPH oxidase isoforms 1 and 4.

Liang CF, Liu JT, Wang Y, Xu A, Vanhoutte PM.

Arterioscler Thromb Vasc Biol. 2013 Apr;33(4):777-84. doi: 10.1161/ATVBAHA.112.301087.

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