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Transcriptional targeting of primary and metastatic tumor neovasculature by an adenoviral type 5 roundabout4 vector in mice.

Lu ZH, Kaliberov S, Sohn RE, Kaliberova L, Curiel DT, Arbeit JM.

PLoS One. 2013 Dec 23;8(12):e83933. doi: 10.1371/journal.pone.0083933. eCollection 2013.


The myeloid-binding peptide adenoviral vector enables multi-organ vascular endothelial gene targeting.

Lu ZH, Kaliberov S, Zhang J, Muz B, Azab AK, Sohn RE, Kaliberova L, Du Y, Curiel DT, Arbeit JM.

Lab Invest. 2014 Aug;94(8):881-92. doi: 10.1038/labinvest.2014.78. Epub 2014 Jun 23.


Combined transductional untargeting/retargeting and transcriptional restriction enhances adenovirus gene targeting and therapy for hepatic colorectal cancer tumors.

Li HJ, Everts M, Yamamoto M, Curiel DT, Herschman HR.

Cancer Res. 2009 Jan 15;69(2):554-64. doi: 10.1158/0008-5472.CAN-08-3209.


MicroRNA silencing improves the tumor specificity of adenoviral transgene expression.

Card PB, Hogg RT, Gil Del Alcazar CR, Gerard RD.

Cancer Gene Ther. 2012 Jul;19(7):451-9. doi: 10.1038/cgt.2012.16. Epub 2012 May 4.


A new model of multi-visceral and bone metastatic prostate cancer with perivascular niche targeting by a novel endothelial specific adenoviral vector.

Lu ZH, Kaliberov S, Sohn RE, Kaliberova L, Du Y, Prior JL, Leib DJ, Chauchereau A, Sehn JK, Curiel DT, Arbeit JM.

Oncotarget. 2017 Feb 14;8(7):12272-12289. doi: 10.18632/oncotarget.14699.


Effective high-capacity gutless adenoviral vectors mediate transgene expression in human glioma cells.

Candolfi M, Curtin JF, Xiong WD, Kroeger KM, Liu C, Rentsendorj A, Agadjanian H, Medina-Kauwe L, Palmer D, Ng P, Lowenstein PR, Castro MG.

Mol Ther. 2006 Sep;14(3):371-81. Epub 2006 Jun 23.


Intratumoral versus intravenous gene therapy using a transcriptionally targeted viral vector in an orthotopic hepatocellular carcinoma rat model.

Kim YI, Ahn BC, Ronald JA, Katzenberg R, Singh A, Paulmurugan R, Ray S, Gambhir SS, Hofmann LV.

J Vasc Interv Radiol. 2012 May;23(5):704-11. doi: 10.1016/j.jvir.2012.01.053. Epub 2012 Mar 2.


Selective induction of tumor-associated antigens in murine pulmonary vasculature using double-targeted adenoviral vectors.

Everts M, Kim-Park SA, Preuss MA, Passineau MJ, Glasgow JN, Pereboev AV, Mahasreshti PJ, Grizzle WE, Reynolds PN, Curiel DT.

Gene Ther. 2005 Jul;12(13):1042-8.


Transductional and transcriptional targeting of adenovirus for clinical applications.

Glasgow JN, Bauerschmitz GJ, Curiel DT, Hemminki A.

Curr Gene Ther. 2004 Mar;4(1):1-14. Review.


Targeting EGFR with metabolically biotinylated fiber-mosaic adenovirus.

Pereboeva L, Komarova S, Roth J, Ponnazhagan S, Curiel DT.

Gene Ther. 2007 Apr;14(8):627-37. Epub 2007 Jan 25.


Hexon modification to improve the activity of oncolytic adenovirus vectors against neoplastic and stromal cells in pancreatic cancer.

Lucas T, Benihoud K, Vigant F, Schmidt CQ, Wortmann A, Bachem MG, Simmet T, Kochanek S.

PLoS One. 2015 Feb 18;10(2):e0117254. doi: 10.1371/journal.pone.0117254. eCollection 2015. Erratum in: PLoS One. 2015;10(4):e0123844. Schmidt, Christoph Q Andreas [corrected to Schmidt, Christoph Q]; Wortmann, Andreas [added].


Quantitative analysis of p53-targeted gene expression and visualization of p53 transcriptional activity following intratumoral administration of adenoviral p53 in vivo.

Ohtani S, Kagawa S, Tango Y, Umeoka T, Tokunaga N, Tsunemitsu Y, Roth JA, Taya Y, Tanaka N, Fujiwara T.

Mol Cancer Ther. 2004 Jan;3(1):93-100.


Transduction of brain dopamine neurons by adenoviral vectors is modulated by CAR expression: rationale for tropism modified vectors in PD gene therapy.

Lewis TB, Glasgow JN, Glandon AM, Curiel DT, Standaert DG.

PLoS One. 2010 Sep 17;5(9). pii: e12672. doi: 10.1371/journal.pone.0012672.


Gene delivery into malignant glioma by infectivity-enhanced adenovirus: in vivo versus in vitro models.

Van Houdt WJ, Wu H, Glasgow JN, Lamfers ML, Dirven CM, Gillespie GY, Curiel DT, Haviv YS.

Neuro Oncol. 2007 Jul;9(3):280-90. Epub 2007 May 23.


Transcriptional targeting in renal cancer cell lines via the human CXCR4 promoter.

Haviv YS, van Houdt WJ, Lu B, Curiel DT, Zhu ZB.

Mol Cancer Ther. 2004 Jun;3(6):687-91.


In vivo retargeting of adenovirus type 5 to alphavbeta6 integrin results in reduced hepatotoxicity and improved tumor uptake following systemic delivery.

Coughlan L, Vallath S, Saha A, Flak M, McNeish IA, Vassaux G, Marshall JF, Hart IR, Thomas GJ.

J Virol. 2009 Jul;83(13):6416-28. doi: 10.1128/JVI.00445-09. Epub 2009 Apr 15.


Replication-competent Ad11p vector (RCAd11p) efficiently transduces and replicates in hormone-refractory metastatic prostate cancer cells.

Sandberg L, Papareddy P, Silver J, Bergh A, Mei YF.

Hum Gene Ther. 2009 Apr;20(4):361-73. doi: 10.1089/hum.2007.124.


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