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Items: 1 to 20 of 121

1.

Hepatocyte-specific high-mobility group box 1 deletion worsens the injury in liver ischemia/reperfusion: a role for intracellular high-mobility group box 1 in cellular protection.

Huang H, Nace GW, McDonald KA, Tai S, Klune JR, Rosborough BR, Ding Q, Loughran P, Zhu X, Beer-Stolz D, Chang EB, Billiar T, Tsung A.

Hepatology. 2014 May;59(5):1984-1997. doi: 10.1002/hep.26976. Epub 2014 Apr 1.

2.

Toll-like receptor 9 inhibition confers protection from liver ischemia-reperfusion injury.

Bamboat ZM, Balachandran VP, Ocuin LM, Obaid H, Plitas G, DeMatteo RP.

Hepatology. 2010 Feb;51(2):621-32. doi: 10.1002/hep.23365.

3.

Cellular-specific role of toll-like receptor 4 in hepatic ischemia-reperfusion injury in mice.

Nace GW, Huang H, Klune JR, Eid RE, Rosborough BR, Korff S, Li S, Shapiro RA, Stolz DB, Sodhi CP, Hackam DJ, Geller DA, Billiar TR, Tsung A.

Hepatology. 2013 Jul;58(1):374-87. doi: 10.1002/hep.26346. Epub 2013 May 27.

4.

Toll-like receptor 4 (TLR4) antagonist eritoran tetrasodium attenuates liver ischemia and reperfusion injury through inhibition of high-mobility group box protein B1 (HMGB1) signaling.

Mcdonald KA, Huang H, Tohme S, Loughran P, Ferrero K, Billiar T, Tsung A.

Mol Med. 2015 Mar 13;20:639-48. doi: 10.2119/molmed.2014.00076.

5.

Damage-associated molecular pattern-activated neutrophil extracellular trap exacerbates sterile inflammatory liver injury.

Huang H, Tohme S, Al-Khafaji AB, Tai S, Loughran P, Chen L, Wang S, Kim J, Billiar T, Wang Y, Tsung A.

Hepatology. 2015 Aug;62(2):600-14. doi: 10.1002/hep.27841. Epub 2015 May 29.

6.

Aag-initiated base excision repair promotes ischemia reperfusion injury in liver, brain, and kidney.

Ebrahimkhani MR, Daneshmand A, Mazumder A, Allocca M, Calvo JA, Abolhassani N, Jhun I, Muthupalani S, Ayata C, Samson LD.

Proc Natl Acad Sci U S A. 2014 Nov 11;111(45):E4878-86. doi: 10.1073/pnas.1413582111. Epub 2014 Oct 27.

7.

Endogenous histones function as alarmins in sterile inflammatory liver injury through Toll-like receptor 9 in mice.

Huang H, Evankovich J, Yan W, Nace G, Zhang L, Ross M, Liao X, Billiar T, Xu J, Esmon CT, Tsung A.

Hepatology. 2011 Sep 2;54(3):999-1008. doi: 10.1002/hep.24501.

8.

High mobility group box 1 release from hepatocytes during ischemia and reperfusion injury is mediated by decreased histone deacetylase activity.

Evankovich J, Cho SW, Zhang R, Cardinal J, Dhupar R, Zhang L, Klune JR, Zlotnicki J, Billiar T, Tsung A.

J Biol Chem. 2010 Dec 17;285(51):39888-97. doi: 10.1074/jbc.M110.128348. Epub 2010 Oct 11.

9.

Hepatocyte free cholesterol lipotoxicity results from JNK1-mediated mitochondrial injury and is HMGB1 and TLR4-dependent.

Gan LT, Van Rooyen DM, Koina ME, McCuskey RS, Teoh NC, Farrell GC.

J Hepatol. 2014 Dec;61(6):1376-84. doi: 10.1016/j.jhep.2014.07.024. Epub 2014 Jul 24.

PMID:
25064435
10.

Interferon regulatory factor 1 mediates acetylation and release of high mobility group box 1 from hepatocytes during murine liver ischemia-reperfusion injury.

Dhupar R, Klune JR, Evankovich J, Cardinal J, Zhang M, Ross M, Murase N, Geller DA, Billiar TR, Tsung A.

Shock. 2011 Mar;35(3):293-301. doi: 10.1097/SHK.0b013e3181f6aab0.

PMID:
20856174
11.

The nuclear factor HMGB1 mediates hepatic injury after murine liver ischemia-reperfusion.

Tsung A, Sahai R, Tanaka H, Nakao A, Fink MP, Lotze MT, Yang H, Li J, Tracey KJ, Geller DA, Billiar TR.

J Exp Med. 2005 Apr 4;201(7):1135-43. Epub 2005 Mar 28.

12.

High-mobility group box-1 in ischemia-reperfusion injury of the heart.

Andrassy M, Volz HC, Igwe JC, Funke B, Eichberger SN, Kaya Z, Buss S, Autschbach F, Pleger ST, Lukic IK, Bea F, Hardt SE, Humpert PM, Bianchi ME, Mairbäurl H, Nawroth PP, Remppis A, Katus HA, Bierhaus A.

Circulation. 2008 Jun 24;117(25):3216-26. doi: 10.1161/CIRCULATIONAHA.108.769331.

13.

ASC/caspase-1/IL-1β signaling triggers inflammatory responses by promoting HMGB1 induction in liver ischemia/reperfusion injury.

Kamo N, Ke B, Ghaffari AA, Shen XD, Busuttil RW, Cheng G, Kupiec-Weglinski JW.

Hepatology. 2013 Jul;58(1):351-62. doi: 10.1002/hep.26320. Epub 2013 May 15.

14.

HMGB1 release induced by liver ischemia involves Toll-like receptor 4 dependent reactive oxygen species production and calcium-mediated signaling.

Tsung A, Klune JR, Zhang X, Jeyabalan G, Cao Z, Peng X, Stolz DB, Geller DA, Rosengart MR, Billiar TR.

J Exp Med. 2007 Nov 26;204(12):2913-23. Epub 2007 Nov 5.

15.

Cutting edge: high-mobility group box 1 preconditioning protects against liver ischemia-reperfusion injury.

Izuishi K, Tsung A, Jeyabalan G, Critchlow ND, Li J, Tracey KJ, Demarco RA, Lotze MT, Fink MP, Geller DA, Billiar TR.

J Immunol. 2006 Jun 15;176(12):7154-8.

16.

Poly(ADP-ribose) polymerase 1-sirtuin 1 functional interplay regulates LPS-mediated high mobility group box 1 secretion.

Walko TD 3rd, Di Caro V, Piganelli J, Billiar TR, Clark RS, Aneja RK.

Mol Med. 2015 Mar 12;20:612-24. doi: 10.2119/molmed.2014.00156.

17.

Identification of Proteins Interacting with Cytoplasmic High-Mobility Group Box 1 during the Hepatocellular Response to Ischemia Reperfusion Injury.

Zhang T, Wei W, Dirsch O, Krüger T, Kan C, Xie C, Kniemeyer O, Fang H, Settmacher U, Dahmen U.

Int J Mol Sci. 2017 Jan 16;18(1). pii: E167. doi: 10.3390/ijms18010167.

18.

The high-mobility group box-1 nuclear factor mediates retinal injury after ischemia reperfusion.

Dvoriantchikova G, Hernandez E, Grant J, Santos AR, Yang H, Ivanov D.

Invest Ophthalmol Vis Sci. 2011 Sep 9;52(10):7187-94. doi: 10.1167/iovs.11-7793.

19.

CD14 contributes to warm hepatic ischemia-reperfusion injury in mice.

Cai C, Shi X, Korff S, Zhang J, Loughran PA, Ruan X, Zhang Y, Liu L, Billiar TR.

Shock. 2013 Aug;40(2):115-21. doi: 10.1097/SHK.0b013e318299d1a7.

20.

HMGB1 plays a critical role in vascular inflammation and lesion formation via toll-like receptor 9.

Hirata Y, Kurobe H, Higashida M, Fukuda D, Shimabukuro M, Tanaka K, Higashikuni Y, Kitagawa T, Sata M.

Atherosclerosis. 2013 Dec;231(2):227-33. doi: 10.1016/j.atherosclerosis.2013.09.010. Epub 2013 Oct 2.

PMID:
24267232

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