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Items: 1 to 20 of 285

1.

Trapping the dynamic acyl carrier protein in fatty acid biosynthesis.

Nguyen C, Haushalter RW, Lee DJ, Markwick PR, Bruegger J, Caldara-Festin G, Finzel K, Jackson DR, Ishikawa F, O'Dowd B, McCammon JA, Opella SJ, Tsai SC, Burkart MD.

Nature. 2014 Jan 16;505(7483):427-31. doi: 10.1038/nature12810. Epub 2013 Dec 22.

2.

Probing the Substrate Specificity and Protein-Protein Interactions of the E. coli Fatty Acid Dehydratase, FabA.

Finzel K, Nguyen C, Jackson DR, Gupta A, Tsai SC, Burkart MD.

Chem Biol. 2015 Nov 19;22(11):1453-60. doi: 10.1016/j.chembiol.2015.09.009. Epub 2015 Oct 29.

3.

Crystal structures of acyl carrier protein in complex with two catalytic partners show a dynamic role in cellular metabolism.

Newmister SA, Sherman DH.

Chembiochem. 2014 May 26;15(8):1079-81. doi: 10.1002/cbic.201402095. Epub 2014 Apr 25.

4.

Interactions of the acyl chain with the Saccharomyces cerevisiae acyl carrier protein.

Perez DR, Leibundgut M, Wider G.

Biochemistry. 2015 Apr 7;54(13):2205-13. doi: 10.1021/bi5014563. Epub 2015 Mar 25.

PMID:
25774789
5.

In vivo functional analyses of the type II acyl carrier proteins of fatty acid biosynthesis.

De Lay NR, Cronan JE.

J Biol Chem. 2007 Jul 13;282(28):20319-28. Epub 2007 May 23.

7.

An ACP structural switch: conformational differences between the apo and holo forms of the actinorhodin polyketide synthase acyl carrier protein.

Evans SE, Williams C, Arthur CJ, Burston SG, Simpson TJ, Crosby J, Crump MP.

Chembiochem. 2008 Oct 13;9(15):2424-32. doi: 10.1002/cbic.200800180.

PMID:
18770515
8.
9.

Mapping a ketosynthase:acyl carrier protein binding interface via unnatural amino acid-mediated photo-cross-linking.

Ye Z, Williams GJ.

Biochemistry. 2014 Dec 9;53(48):7494-502. doi: 10.1021/bi500936u. Epub 2014 Nov 26.

PMID:
25427130
10.

The chain-flipping mechanism of ACP (acyl carrier protein)-dependent enzymes appears universal.

Cronan JE.

Biochem J. 2014 Jun 1;460(2):157-63. doi: 10.1042/BJ20140239. Review.

PMID:
24825445
11.

Molecular dynamics simulations of the Apo-, Holo-, and acyl-forms of Escherichia coli acyl carrier protein.

Chan DI, Stockner T, Tieleman DP, Vogel HJ.

J Biol Chem. 2008 Nov 28;283(48):33620-9. doi: 10.1074/jbc.M805323200. Epub 2008 Sep 22.

12.

Solution structure and backbone dynamics of the holo form of the frenolicin acyl carrier protein.

Li Q, Khosla C, Puglisi JD, Liu CW.

Biochemistry. 2003 Apr 29;42(16):4648-57.

PMID:
12705828
13.
14.

Structural studies of fatty acyl-(acyl carrier protein) thioesters reveal a hydrophobic binding cavity that can expand to fit longer substrates.

Roujeinikova A, Simon WJ, Gilroy J, Rice DW, Rafferty JB, Slabas AR.

J Mol Biol. 2007 Jan 5;365(1):135-45. Epub 2006 Sep 23.

PMID:
17059829
15.

The conserved modular elements of the acyl carrier proteins of lipid synthesis are only partially interchangeable.

Zhu L, Cronan JE.

J Biol Chem. 2015 May 29;290(22):13791-9. doi: 10.1074/jbc.M115.648402. Epub 2015 Apr 10.

16.

Probing the Interactions of early polyketide intermediates with the Actinorhodin ACP from S. coelicolor A3(2).

Evans SE, Williams C, Arthur CJ, Płoskoń E, Wattana-amorn P, Cox RJ, Crosby J, Willis CL, Simpson TJ, Crump MP.

J Mol Biol. 2009 Jun 12;389(3):511-28. doi: 10.1016/j.jmb.2009.03.072. Epub 2009 Apr 8.

PMID:
19361520
17.

Identification and Characterization of FabA from the Type II Fatty Acid Synthase of Streptomyces coelicolor.

Singh R, Reynolds KA.

J Nat Prod. 2016 Jan 22;79(1):240-3. doi: 10.1021/acs.jnatprod.5b00560. Epub 2016 Jan 5.

PMID:
26731437
18.

Fatty acid synthesis. Role of active site histidines and lysine in Cys-His-His-type beta-ketoacyl-acyl carrier protein synthases.

von Wettstein-Knowles P, Olsen JG, McGuire KA, Henriksen A.

FEBS J. 2006 Feb;273(4):695-710.

19.

A mechanism based protein crosslinker for acyl carrier protein dehydratases.

Meier JL, Haushalter RW, Burkart MD.

Bioorg Med Chem Lett. 2010 Aug 15;20(16):4936-9. doi: 10.1016/j.bmcl.2010.06.028. Epub 2010 Jun 17.

20.

Molecular dynamics simulations of beta-ketoacyl-, beta-hydroxyacyl-, and trans-2-enoyl-acyl carrier proteins of Escherichia coli.

Chan DI, Tieleman DP, Vogel HJ.

Biochemistry. 2010 Apr 6;49(13):2860-8. doi: 10.1021/bi901713r.

PMID:
20180600

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