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Items: 1 to 20 of 122

1.

Neutralization of leukotriene C4 and D4 activity by monoclonal and single-chain antibodies.

Kawakami Y, Hirano S, Kinoshita M, Otsuki A, Suzuki-Yamamoto T, Suzuki M, Kimoto M, Sasabe S, Fukushima M, Kishimoto K, Izumi T, Oga T, Narumiya S, Sugahara M, Miyano M, Yamamoto S, Takahashi Y.

Biochim Biophys Acta. 2014 Jun;1840(6):1625-33. doi: 10.1016/j.bbagen.2013.12.016. Epub 2013 Dec 20.

PMID:
24361619
2.

Functional expression of single-chain antibody to leukotriene C(4).

Kawakami Y, Yamashita C, Kashiwase Y, Morinaka T, Suzuki-Yamamoto T, Yamashita H, Kimoto M, Tsuji H, Kurahashi Y, Daiyasu H, Toh H, Sugahara M, Miyano M, Yamamoto S, Takahashi Y.

Biochem Biophys Res Commun. 2010 Feb 12;392(3):421-5. doi: 10.1016/j.bbrc.2010.01.039. Epub 2010 Jan 15.

PMID:
20079714
3.

Cutting edge: Leukotriene C4 activates mouse platelets in plasma exclusively through the type 2 cysteinyl leukotriene receptor.

Cummings HE, Liu T, Feng C, Laidlaw TM, Conley PB, Kanaoka Y, Boyce JA.

J Immunol. 2013 Dec 15;191(12):5807-10. doi: 10.4049/jimmunol.1302187. Epub 2013 Nov 15.

4.

Leukotriene C4 induces bronchoconstriction and airway vascular hyperpermeability via the cysteinyl leukotriene receptor 2 in S-hexyl glutathione-treated guinea pigs.

Yonetomi Y, Sekioka T, Kadode M, Kitamine T, Kamiya A, Matsumura N, Fujita M, Kawabata K.

Eur J Pharmacol. 2015 May 5;754:98-104. doi: 10.1016/j.ejphar.2015.02.014. Epub 2015 Feb 20.

PMID:
25704617
5.

Cysteinyl-leukotrienes and their receptors in asthma and other inflammatory diseases: critical update and emerging trends.

Capra V, Thompson MD, Sala A, Cole DE, Folco G, Rovati GE.

Med Res Rev. 2007 Jul;27(4):469-527. Review.

PMID:
16894531
6.

Agonist- and T(H)2 cytokine-induced up-regulation of cysteinyl leukotriene receptor messenger RNA in human monocytes.

Shirasaki H, Seki N, Fujita M, Kikuchi M, Kanaizumi E, Watanabe K, Himi T.

Ann Allergy Asthma Immunol. 2007 Oct;99(4):340-7.

PMID:
17941281
7.

Leukotriene D4 and prostaglandin E2 signals synergize and potentiate vascular inflammation in a mast cell-dependent manner through cysteinyl leukotriene receptor 1 and E-prostanoid receptor 3.

Kondeti V, Al-Azzam N, Duah E, Thodeti CK, Boyce JA, Paruchuri S.

J Allergy Clin Immunol. 2016 Jan;137(1):289-298. doi: 10.1016/j.jaci.2015.06.030. Epub 2015 Aug 5.

8.

Identification of GPR99 protein as a potential third cysteinyl leukotriene receptor with a preference for leukotriene E4 ligand.

Kanaoka Y, Maekawa A, Austen KF.

J Biol Chem. 2013 Apr 19;288(16):10967-72. doi: 10.1074/jbc.C113.453704. Epub 2013 Mar 15.

9.

Functional characterisation of receptors for cysteinyl leukotrienes in smooth muscle.

Jonsson EW.

Acta Physiol Scand Suppl. 1998 Mar;641:1-55. Review.

PMID:
9597121
10.

Cysteinyl leukotriene receptor 1 mediates LTD4-induced activation of mouse microglial cells in vitro.

Yu SY, Zhang XY, Wang XR, Xu DM, Chen L, Zhang LH, Fang SH, Lu YB, Zhang WP, Wei EQ.

Acta Pharmacol Sin. 2014 Jan;35(1):33-40. doi: 10.1038/aps.2013.130. Epub 2013 Oct 21.

11.

Guinea pig cysteinyl leukotriene receptor 2 (gpCysLT2) mediates cell proliferation and intracellular calcium mobilization by LTC4 and LTD4.

Ito Y, Hirano M, Umemoto N, Zang L, Wang Z, Oka T, Shimada Y, Nishimura Y, Kurokawa I, Mizutani H, Tanaka T.

BMB Rep. 2008 Feb 29;41(2):139-45.

12.

Pharmacodynamic properties of leukotriene receptor antagonists.

Nicosia S.

Monaldi Arch Chest Dis. 1999 Jun;54(3):242-6. Review.

PMID:
10441979
13.

The Y54(L)W mutation of anti-leukotriene C4 single-chain antibody increases affinity to leukotriene E4.

Kawakami Y, Kinoshita M, Mori Y, Okochi S, Hirano S, Shimoda I, Kanzaki K, Suzuki-Yamamoto T, Kimoto M, Sugahara M, Hori T, Saino H, Miyano M, Yamamoto S, Takahashi Y.

J Biochem. 2017 Jan;161(1):79-86. doi: 10.1093/jb/mvw055. Epub 2016 Sep 20.

PMID:
27650603
14.

Cysteinyl leukotriene receptors.

Evans JF.

Prostaglandins Other Lipid Mediat. 2002 Aug;68-69:587-97. Review.

PMID:
12432945
15.
16.

Leukotriene E4-induced pulmonary inflammation is mediated by the P2Y12 receptor.

Paruchuri S, Tashimo H, Feng C, Maekawa A, Xing W, Jiang Y, Kanaoka Y, Conley P, Boyce JA.

J Exp Med. 2009 Oct 26;206(11):2543-55. doi: 10.1084/jem.20091240. Epub 2009 Oct 12.

17.

Leukotriene C4 Potentiates IL-33-Induced Group 2 Innate Lymphoid Cell Activation and Lung Inflammation.

Lund SJ, Portillo A, Cavagnero K, Baum RE, Naji LH, Badrani JH, Mehta A, Croft M, Broide DH, Doherty TA.

J Immunol. 2017 Aug 1;199(3):1096-1104. doi: 10.4049/jimmunol.1601569. Epub 2017 Jun 30.

PMID:
28667163
18.

Pharmacological characterization of the first potent and selective antagonist at the cysteinyl leukotriene 2 (CysLT(2)) receptor.

Wunder F, Tinel H, Kast R, Geerts A, Becker EM, Kolkhof P, Hütter J, Ergüden J, Härter M.

Br J Pharmacol. 2010 May;160(2):399-409. doi: 10.1111/j.1476-5381.2010.00730.x.

19.
20.

Characterization of the human cysteinyl leukotriene CysLT1 receptor.

Lynch KR, O'Neill GP, Liu Q, Im DS, Sawyer N, Metters KM, Coulombe N, Abramovitz M, Figueroa DJ, Zeng Z, Connolly BM, Bai C, Austin CP, Chateauneuf A, Stocco R, Greig GM, Kargman S, Hooks SB, Hosfield E, Williams DL Jr, Ford-Hutchinson AW, Caskey CT, Evans JF.

Nature. 1999 Jun 24;399(6738):789-93.

PMID:
10391245

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