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Items: 1 to 20 of 167

1.

The effect of FFAR1 on pioglitazone-mediated attenuation of palmitic acid-induced oxidative stress and apoptosis in βTC6 cells.

Shen X, Yang L, Yan S, Wei W, Liang L, Zheng H, Cai X.

Metabolism. 2014 Mar;63(3):335-51. doi: 10.1016/j.metabol.2013.11.003. Epub 2013 Nov 11.

PMID:
24360748
2.

Fetuin A promotes lipotoxicity in β cells through the TLR4 signaling pathway and the role of pioglitazone in anti-lipotoxicity.

Shen X, Yang L, Yan S, Zheng H, Liang L, Cai X, Liao M.

Mol Cell Endocrinol. 2015 Sep 5;412:1-11. doi: 10.1016/j.mce.2015.05.014. Epub 2015 May 15.

PMID:
25986658
3.

Effect of PANDER in βTC6-cell lipoapoptosis and the protective role of exendin-4.

Xiang JN, Chen DL, Yang LY.

Biochem Biophys Res Commun. 2012 May 18;421(4):701-6. doi: 10.1016/j.bbrc.2012.04.065. Epub 2012 Apr 21.

PMID:
22542939
4.

Pioglitazone attenuates fatty acid-induced oxidative stress and apoptosis in pancreatic beta-cells.

Saitoh Y, Chun-ping C, Noma K, Ueno H, Mizuta M, Nakazato M.

Diabetes Obes Metab. 2008 Jul;10(7):564-73. Epub 2007 Jun 26.

PMID:
17593232
5.

Role of ERp46 in β-cell lipoapoptosis through endoplasmic reticulum stress pathway as well as the protective effect of exendin-4.

Chen DL, Xiang JN, Yang LY.

Biochem Biophys Res Commun. 2012 Sep 28;426(3):324-9. doi: 10.1016/j.bbrc.2012.08.072. Epub 2012 Aug 23.

PMID:
22935416
6.

The relationship between GPR40 and lipotoxicity of the pancreatic β-cells as well as the effect of pioglitazone.

Wu P, Yang L, Shen X.

Biochem Biophys Res Commun. 2010 Dec 3;403(1):36-9. doi: 10.1016/j.bbrc.2010.10.105. Epub 2010 Oct 29.

PMID:
21036144
7.

Essential role of Nrf2 in the protective effect of lipoic acid against lipoapoptosis in hepatocytes.

Valdecantos MP, Prieto-Hontoria PL, Pardo V, Módol T, Santamaría B, Weber M, Herrero L, Serra D, Muntané J, Cuadrado A, Moreno-Aliaga MJ, Alfredo Martínez J, Valverde ÁM.

Free Radic Biol Med. 2015 Jul;84:263-78. doi: 10.1016/j.freeradbiomed.2015.03.019. Epub 2015 Apr 1.

PMID:
25841776
8.

Activation of extracellular signal-regulated protein kinases 1 and 2 (ERK1/2) by free fatty acid receptor 1 (FFAR1/GPR40) protects from palmitate-induced beta cell death, but plays no role in insulin secretion.

Panse M, Gerst F, Kaiser G, Teutsch CA, Dölker R, Wagner R, Häring HU, Ullrich S.

Cell Physiol Biochem. 2015;35(4):1537-45. doi: 10.1159/000373969. Epub 2015 Mar 12.

9.

PPAR-γ activation increases insulin secretion through the up-regulation of the free fatty acid receptor GPR40 in pancreatic β-cells.

Kim HS, Hwang YC, Koo SH, Park KS, Lee MS, Kim KW, Lee MK.

PLoS One. 2013;8(1):e50128. doi: 10.1371/journal.pone.0050128. Epub 2013 Jan 23.

10.

Molecular mechanism by which pioglitazone preserves pancreatic beta-cells in obese diabetic mice: evidence for acute and chronic actions as a PPARgamma agonist.

Kanda Y, Shimoda M, Hamamoto S, Tawaramoto K, Kawasaki F, Hashiramoto M, Nakashima K, Matsuki M, Kaku K.

Am J Physiol Endocrinol Metab. 2010 Feb;298(2):E278-86. doi: 10.1152/ajpendo.00388.2009. Epub 2009 Nov 17.

11.
12.

Octaphlorethol A, a novel phenolic compound isolated from Ishige foliacea, protects against streptozotocin-induced pancreatic β cell damage by reducing oxidative stress and apoptosis.

Lee SH, Kang SM, Ko SC, Kang MC, Jeon YJ.

Food Chem Toxicol. 2013 Sep;59:643-9. doi: 10.1016/j.fct.2013.07.011. Epub 2013 Jul 16.

PMID:
23871829
13.

Peroxisome proliferator-activated receptor gamma up-regulates the Bcl-2 anti-apoptotic protein in neurons and induces mitochondrial stabilization and protection against oxidative stress and apoptosis.

Fuenzalida K, Quintanilla R, Ramos P, Piderit D, Fuentealba RA, Martinez G, Inestrosa NC, Bronfman M.

J Biol Chem. 2007 Dec 21;282(51):37006-15. Epub 2007 Oct 25.

14.

Mitochondrial reactive oxygen species (ROS) inhibition ameliorates palmitate-induced INS-1 beta cell death.

Lin N, Chen H, Zhang H, Wan X, Su Q.

Endocrine. 2012 Aug;42(1):107-17. doi: 10.1007/s12020-012-9633-z. Epub 2012 Feb 20.

PMID:
22350662
15.

Suppression of KATP channel activity protects murine pancreatic beta cells against oxidative stress.

Gier B, Krippeit-Drews P, Sheiko T, Aguilar-Bryan L, Bryan J, Düfer M, Drews G.

J Clin Invest. 2009 Nov;119(11):3246-56. doi: 10.1172/JCI38817. Epub 2009 Oct 1.

16.

Metformin attenuates palmitate-induced endoplasmic reticulum stress, serine phosphorylation of IRS-1 and apoptosis in rat insulinoma cells.

Simon-Szabó L, Kokas M, Mandl J, Kéri G, Csala M.

PLoS One. 2014 Jun 4;9(6):e97868. doi: 10.1371/journal.pone.0097868. eCollection 2014.

17.

Suppression of Grb2 expression improved hepatic steatosis, oxidative stress, and apoptosis induced by palmitic acid in vitro partly through insulin signaling alteration.

Shan X, Miao Y, Fan R, Song C, Wu G, Wan Z, Zhu J, Sun G, Zha W, Mu X, Zhou G, Chen Y.

In Vitro Cell Dev Biol Anim. 2013 Sep;49(8):576-82. doi: 10.1007/s11626-013-9646-9. Epub 2013 Jun 15.

PMID:
23771793
18.
19.

[Effects of glucagon-like peptide-1 on the free fatty acid-induced expression of pancreatic derived factor in cultured β-TC3 cell line].

Chen S, Cao XP, Xiao HP, Li YB.

Zhonghua Yi Xue Za Zhi. 2011 May 31;91(20):1413-6. Chinese.

PMID:
21756815
20.

Cinnamtannin D-1 protects pancreatic β-cells from palmitic acid-induced apoptosis by attenuating oxidative stress.

Wang T, Sun P, Chen L, Huang Q, Chen K, Jia Q, Li Y, Wang H.

J Agric Food Chem. 2014 Jun 4;62(22):5038-45. doi: 10.1021/jf500387d. Epub 2014 May 22.

PMID:
24815044

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