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Items: 1 to 20 of 86

1.

Transcriptome-based functional classifiers for direct immunotoxicity.

Shao J, Berger LF, Hendriksen PJ, Peijnenburg AA, van Loveren H, Volger OL.

Arch Toxicol. 2014 Mar;88(3):673-89. doi: 10.1007/s00204-013-1179-1. Epub 2013 Dec 20.

PMID:
24356939
2.

Successful validation of genomic biomarkers for human immunotoxicity in Jurkat T cells in vitro.

Schmeits PC, Shao J, van der Krieken DA, Volger OL, van Loveren H, Peijnenburg AA, Hendriksen PJ.

J Appl Toxicol. 2015 Jul;35(7):831-41. doi: 10.1002/jat.3079. Epub 2014 Nov 25.

PMID:
25424538
3.

Toxicogenomics-based identification of mechanisms for direct immunotoxicity.

Shao J, Katika MR, Schmeits PC, Hendriksen PJ, van Loveren H, Peijnenburg AA, Volger OL.

Toxicol Sci. 2013 Oct;135(2):328-46. doi: 10.1093/toxsci/kft151. Epub 2013 Jul 3.

PMID:
23824090
4.

Inhibition of CXCL12-mediated chemotaxis of Jurkat cells by direct immunotoxicants.

Shao J, Stout I, Volger OL, Hendriksen PJ, van Loveren H, Peijnenburg AA.

Arch Toxicol. 2016 Jul;90(7):1685-94. doi: 10.1007/s00204-015-1585-7. Epub 2015 Aug 28.

PMID:
26314263
5.

Assessment of the usefulness of the murine cytotoxic T cell line CTLL-2 for immunotoxicity screening by transcriptomics.

Schmeits PC, Volger OL, Zandvliet ET, van Loveren H, Peijnenburg AA, Hendriksen PJ.

Toxicol Lett. 2013 Feb 13;217(1):1-13. doi: 10.1016/j.toxlet.2012.12.005. Epub 2012 Dec 17.

PMID:
23253260
6.

Toxicogenomics in the assessment of immunotoxicity.

Baken KA, Vandebriel RJ, Pennings JL, Kleinjans JC, van Loveren H.

Methods. 2007 Jan;41(1):132-41. Review.

PMID:
17161310
7.

Risk assessment in immunotoxicology. I. Sensitivity and predictability of immune tests.

Luster MI, Portier C, Pait DG, White KL Jr, Gennings C, Munson AE, Rosenthal GJ.

Fundam Appl Toxicol. 1992 Feb;18(2):200-10.

PMID:
1534777
8.

Utilization of CDKN1A/p21 gene for class discrimination of DNA damage-induced clastogenicity.

Sakai R, Kondo C, Oka H, Miyajima H, Kubo K, Uehara T.

Toxicology. 2014 Jan 6;315:8-16. doi: 10.1016/j.tox.2013.10.009. Epub 2013 Nov 6.

PMID:
24211769
9.

Safety and nutritional assessment of GM plants and derived food and feed: the role of animal feeding trials.

EFSA GMO Panel Working Group on Animal Feeding Trials..

Food Chem Toxicol. 2008 Mar;46 Suppl 1:S2-70. doi: 10.1016/j.fct.2008.02.008. Epub 2008 Feb 13. Review.

PMID:
18328408
10.

High-density real-time PCR-based in vivo toxicogenomic screen to predict organ-specific toxicity.

Fabian G, Farago N, Feher LZ, Nagy LI, Kulin S, Kitajka K, Bito T, Tubak V, Katona RL, Tiszlavicz L, Puskas LG.

Int J Mol Sci. 2011;12(9):6116-34. doi: 10.3390/ijms12096116. Epub 2011 Sep 19.

11.

Transcriptomic profile indicative of immunotoxic exposure: in vitro studies in peripheral blood mononuclear cells.

Hochstenbach K, van Leeuwen DM, Gmuender H, Stølevik SB, Nygaard UC, Løvik M, Granum B, Namork E, van Delft JH, van Loveren H.

Toxicol Sci. 2010 Nov;118(1):19-30. doi: 10.1093/toxsci/kfq239. Epub 2010 Aug 11.

PMID:
20702593
12.

The accuracy of extended histopathology to detect immunotoxic chemicals.

Germolec DR, Kashon M, Nyska A, Kuper CF, Portier C, Kommineni C, Johnson KA, Luster MI.

Toxicol Sci. 2004 Dec;82(2):504-14. Epub 2004 Sep 1.

PMID:
15342959
13.

Transcriptome analysis of the human T lymphocyte cell line Jurkat and human peripheral blood mononuclear cells exposed to deoxynivalenol (DON): New mechanistic insights.

Katika MR, Hendriksen PJ, Shao J, van Loveren H, Peijnenburg A.

Toxicol Appl Pharmacol. 2012 Oct 1;264(1):51-64. doi: 10.1016/j.taap.2012.07.017. Epub 2012 Jul 28.

PMID:
22846391
14.

Inter-laboratory study of human in vitro toxicogenomics-based tests as alternative methods for evaluating chemical carcinogenicity: a bioinformatics perspective.

Herwig R, Gmuender H, Corvi R, Bloch KM, Brandenburg A, Castell J, Ceelen L, Chesne C, Doktorova TY, Jennen D, Jennings P, Limonciel A, Lock EA, McMorrow T, Phrakonkham P, Radford R, Slattery C, Stierum R, Vilardell M, Wittenberger T, Yildirimman R, Ryan M, Rogiers V, Kleinjans J.

Arch Toxicol. 2016 Sep;90(9):2215-29. doi: 10.1007/s00204-015-1617-3. Epub 2015 Nov 2.

PMID:
26525393
15.

Immunotoxicogenomics: the potential of genomics technology in the immunotoxicity risk assessment process.

Luebke RW, Holsapple MP, Ladics GS, Luster MI, Selgrade M, Smialowicz RJ, Woolhiser MR, Germolec DR.

Toxicol Sci. 2006 Nov;94(1):22-7. Epub 2006 Aug 1.

16.

Consistency of predictive signature genes and classifiers generated using different microarray platforms.

Fan X, Lobenhofer EK, Chen M, Shi W, Huang J, Luo J, Zhang J, Walker SJ, Chu TM, Li L, Wolfinger R, Bao W, Paules RS, Bushel PR, Li J, Shi T, Nikolskaya T, Nikolsky Y, Hong H, Deng Y, Cheng Y, Fang H, Shi L, Tong W.

Pharmacogenomics J. 2010 Aug;10(4):247-57. doi: 10.1038/tpj.2010.34.

17.

Development of a toxicogenomics in vitro assay for the efficient characterization of compounds.

Yang Y, Abel SJ, Ciurlionis R, Waring JF.

Pharmacogenomics. 2006 Mar;7(2):177-86.

PMID:
16515397
18.
19.

Finding maximal transcriptome differences between reprotoxic and non-reprotoxic phthalate responses in rat testis.

Yuan X, Jonker MJ, de Wilde J, Verhoef A, Wittink FR, van Benthem J, Bessems JG, Hakkert BC, Kuiper RV, van Steeg H, Breit TM, Luijten M.

J Appl Toxicol. 2011 Jul;31(5):421-30. doi: 10.1002/jat.1601. Epub 2010 Nov 9.

PMID:
21061450

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