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Items: 1 to 20 of 106

1.

Recognition of cytosolic DNA by cGAS and other STING-dependent sensors.

Bhat N, Fitzgerald KA.

Eur J Immunol. 2014 Mar;44(3):634-40. doi: 10.1002/eji.201344127. Epub 2014 Jan 13. Review.

2.

Regulation and function of the cGAS-STING pathway of cytosolic DNA sensing.

Chen Q, Sun L, Chen ZJ.

Nat Immunol. 2016 Sep 20;17(10):1142-9. doi: 10.1038/ni.3558. Review.

PMID:
27648547
3.

The cGAS-cGAMP-STING pathway of cytosolic DNA sensing and signaling.

Cai X, Chiu YH, Chen ZJ.

Mol Cell. 2014 Apr 24;54(2):289-96. doi: 10.1016/j.molcel.2014.03.040. Review.

4.

Structural and functional analyses of DNA-sensing and immune activation by human cGAS.

Kato K, Ishii R, Goto E, Ishitani R, Tokunaga F, Nureki O.

PLoS One. 2013 Oct 7;8(10):e76983. doi: 10.1371/journal.pone.0076983. eCollection 2013.

5.

cGAS and Ifi204 cooperate to produce type I IFNs in response to Francisella infection.

Storek KM, Gertsvolf NA, Ohlson MB, Monack DM.

J Immunol. 2015 Apr 1;194(7):3236-45. doi: 10.4049/jimmunol.1402764. Epub 2015 Feb 20.

6.

Human plasmacytoid dentritic cells elicit a Type I Interferon response by sensing DNA via the cGAS-STING signaling pathway.

Bode C, Fox M, Tewary P, Steinhagen A, Ellerkmann RK, Klinman D, Baumgarten G, Hornung V, Steinhagen F.

Eur J Immunol. 2016 Jul;46(7):1615-21. doi: 10.1002/eji.201546113. Epub 2016 May 27.

7.

Cyclic GMP-AMP synthase is a cytosolic DNA sensor that activates the type I interferon pathway.

Sun L, Wu J, Du F, Chen X, Chen ZJ.

Science. 2013 Feb 15;339(6121):786-91. doi: 10.1126/science.1232458. Epub 2012 Dec 20.

8.

The cytosolic DNA sensor cGAS forms an oligomeric complex with DNA and undergoes switch-like conformational changes in the activation loop.

Zhang X, Wu J, Du F, Xu H, Sun L, Chen Z, Brautigam CA, Zhang X, Chen ZJ.

Cell Rep. 2014 Feb 13;6(3):421-30. doi: 10.1016/j.celrep.2014.01.003. Epub 2014 Jan 23.

9.

The cGAS-STING pathway for DNA sensing.

Xiao TS, Fitzgerald KA.

Mol Cell. 2013 Jul 25;51(2):135-9. doi: 10.1016/j.molcel.2013.07.004. Review.

10.

DNA sensing unchained.

Ablasser A, Hornung V.

Cell Res. 2013 May;23(5):585-7. doi: 10.1038/cr.2013.28. Epub 2013 Feb 19.

11.

Crosstalk between the cGAS DNA sensor and Beclin-1 autophagy protein shapes innate antimicrobial immune responses.

Liang Q, Seo GJ, Choi YJ, Kwak MJ, Ge J, Rodgers MA, Shi M, Leslie BJ, Hopfner KP, Ha T, Oh BH, Jung JU.

Cell Host Microbe. 2014 Feb 12;15(2):228-38. doi: 10.1016/j.chom.2014.01.009.

12.

Cell intrinsic immunity spreads to bystander cells via the intercellular transfer of cGAMP.

Ablasser A, Schmid-Burgk JL, Hemmerling I, Horvath GL, Schmidt T, Latz E, Hornung V.

Nature. 2013 Nov 28;503(7477):530-4. doi: 10.1038/nature12640. Epub 2013 Sep 29.

13.

cGAS-cGAMP-STING: The three musketeers of cytosolic DNA sensing and signaling.

Tao J, Zhou X, Jiang Z.

IUBMB Life. 2016 Nov;68(11):858-870. doi: 10.1002/iub.1566. Epub 2016 Oct 5. Review.

PMID:
27706894
14.

Cytosolic RNA:DNA hybrids activate the cGAS-STING axis.

Mankan AK, Schmidt T, Chauhan D, Goldeck M, Höning K, Gaidt M, Kubarenko AV, Andreeva L, Hopfner KP, Hornung V.

EMBO J. 2014 Dec 17;33(24):2937-46. doi: 10.15252/embj.201488726. Epub 2014 Nov 25.

15.

Modified vaccinia virus Ankara triggers type I IFN production in murine conventional dendritic cells via a cGAS/STING-mediated cytosolic DNA-sensing pathway.

Dai P, Wang W, Cao H, Avogadri F, Dai L, Drexler I, Joyce JA, Li XD, Chen Z, Merghoub T, Shuman S, Deng L.

PLoS Pathog. 2014 Apr 17;10(4):e1003989. doi: 10.1371/journal.ppat.1003989. eCollection 2014 Apr.

16.

Listeria monocytogenes induces IFNβ expression through an IFI16-, cGAS- and STING-dependent pathway.

Hansen K, Prabakaran T, Laustsen A, Jørgensen SE, Rahbæk SH, Jensen SB, Nielsen R, Leber JH, Decker T, Horan KA, Jakobsen MR, Paludan SR.

EMBO J. 2014 Aug 1;33(15):1654-66. doi: 10.15252/embj.201488029. Epub 2014 Jun 26.

17.

Structural mechanism of cytosolic DNA sensing by cGAS.

Civril F, Deimling T, de Oliveira Mann CC, Ablasser A, Moldt M, Witte G, Hornung V, Hopfner KP.

Nature. 2013 Jun 20;498(7454):332-7. doi: 10.1038/nature12305. Epub 2013 May 30.

18.

Identification of a negative feedback loop between cyclic di-GMP-induced levels of IFI16 and p202 cytosolic DNA sensors and STING.

Panchanathan R, Liu H, Xin D, Choubey D.

Innate Immun. 2014 Oct;20(7):751-9. doi: 10.1177/1753425913507097. Epub 2013 Oct 16.

PMID:
24131791
19.

Innate immune recognition of DNA: A recent history.

Dempsey A, Bowie AG.

Virology. 2015 May;479-480:146-52. doi: 10.1016/j.virol.2015.03.013. Epub 2015 Mar 26. Review.

20.

Both STING and MAVS fish orthologs contribute to the induction of interferon mediated by RIG-I.

Biacchesi S, Mérour E, Lamoureux A, Bernard J, Brémont M.

PLoS One. 2012;7(10):e47737. doi: 10.1371/journal.pone.0047737. Epub 2012 Oct 16.

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