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Items: 1 to 20 of 165

1.

Poly(ADP-ribose) binding to Chk1 at stalled replication forks is required for S-phase checkpoint activation.

Min W, Bruhn C, Grigaravicius P, Zhou ZW, Li F, Krüger A, Siddeek B, Greulich KO, Popp O, Meisezahl C, Calkhoven CF, Bürkle A, Xu X, Wang ZQ.

Nat Commun. 2013;4:2993. doi: 10.1038/ncomms3993.

PMID:
24356582
2.

Poly(ADP-ribose) polymerase 1 modulates the lethality of CHK1 inhibitors in carcinoma cells.

Mitchell C, Park M, Eulitt P, Yang C, Yacoub A, Dent P.

Mol Pharmacol. 2010 Nov;78(5):909-17. doi: 10.1124/mol.110.067199. Epub 2010 Aug 9. Erratum in: Mol Pharmacol. 2011 Jan;79(1):207-9.

3.

Poly(ADP-ribose)-mediated interplay of XPA and PARP1 leads to reciprocal regulation of protein function.

Fischer JM, Popp O, Gebhard D, Veith S, Fischbach A, Beneke S, Leitenstorfer A, Bergemann J, Scheffner M, Ferrando-May E, Mangerich A, Bürkle A.

FEBS J. 2014 Aug;281(16):3625-41. doi: 10.1111/febs.12885. Epub 2014 Jul 21.

4.

Differential and Concordant Roles for Poly(ADP-Ribose) Polymerase 1 and Poly(ADP-Ribose) in Regulating WRN and RECQL5 Activities.

Khadka P, Hsu JK, Veith S, Tadokoro T, Shamanna RA, Mangerich A, Croteau DL, Bohr VA.

Mol Cell Biol. 2015 Dec;35(23):3974-89. doi: 10.1128/MCB.00427-15. Epub 2015 Sep 21.

5.

Poly(ADP-ribose) Polymerase 1 Modulates Interaction of the Nucleotide Excision Repair Factor XPC-RAD23B with DNA via Poly(ADP-ribosyl)ation.

Maltseva EA, Rechkunova NI, Sukhanova MV, Lavrik OI.

J Biol Chem. 2015 Sep 4;290(36):21811-20. doi: 10.1074/jbc.M115.646638. Epub 2015 Jul 13.

6.

PARG is dispensable for recovery from transient replicative stress but required to prevent detrimental accumulation of poly(ADP-ribose) upon prolonged replicative stress.

Illuzzi G, Fouquerel E, Amé JC, Noll A, Rehmet K, Nasheuer HP, Dantzer F, Schreiber V.

Nucleic Acids Res. 2014 Jul;42(12):7776-92. doi: 10.1093/nar/gku505. Epub 2014 Jun 6.

7.

Molecular mechanism of poly(ADP-ribosyl)ation by PARP1 and identification of lysine residues as ADP-ribose acceptor sites.

Altmeyer M, Messner S, Hassa PO, Fey M, Hottiger MO.

Nucleic Acids Res. 2009 Jun;37(11):3723-38. doi: 10.1093/nar/gkp229. Epub 2009 Apr 16.

8.

A nuclear poly(ADP-ribose)-dependent signalosome confers DNA damage-induced IkappaB kinase activation.

Stilmann M, Hinz M, Arslan SC, Zimmer A, Schreiber V, Scheidereit C.

Mol Cell. 2009 Nov 13;36(3):365-78. doi: 10.1016/j.molcel.2009.09.032.

9.

Kinase-independent function of checkpoint kinase 1 (Chk1) in the replication of damaged DNA.

Speroni J, Federico MB, Mansilla SF, Soria G, Gottifredi V.

Proc Natl Acad Sci U S A. 2012 May 8;109(19):7344-9. doi: 10.1073/pnas.1116345109. Epub 2012 Apr 23.

10.

The expression of poly(ADP-ribose) polymerase during differentiation-linked DNA replication reveals that it is a component of the multiprotein DNA replication complex.

Simbulan-Rosenthal CM, Rosenthal DS, Hilz H, Hickey R, Malkas L, Applegren N, Wu Y, Bers G, Smulson ME.

Biochemistry. 1996 Sep 10;35(36):11622-33.

PMID:
8794742
11.

Inhibition of Aurora-B kinase activity by poly(ADP-ribosyl)ation in response to DNA damage.

Monaco L, Kolthur-Seetharam U, Loury R, Murcia JM, de Murcia G, Sassone-Corsi P.

Proc Natl Acad Sci U S A. 2005 Oct 4;102(40):14244-8. Epub 2005 Sep 22.

12.

Centromere proteins Cenpa, Cenpb, and Bub3 interact with poly(ADP-ribose) polymerase-1 protein and are poly(ADP-ribosyl)ated.

Saxena A, Saffery R, Wong LH, Kalitsis P, Choo KH.

J Biol Chem. 2002 Jul 26;277(30):26921-6. Epub 2002 May 13.

13.

Poly(ADP-ribose) polymerase 1 modulates the lethality of CHK1 inhibitors in mammary tumors.

Tang Y, Hamed HA, Poklepovic A, Dai Y, Grant S, Dent P.

Mol Pharmacol. 2012 Aug;82(2):322-32. doi: 10.1124/mol.112.078907. Epub 2012 May 17.

14.

And-1 coordinates with Claspin for efficient Chk1 activation in response to replication stress.

Hao J, de Renty C, Li Y, Xiao H, Kemp MG, Han Z, DePamphilis ML, Zhu W.

EMBO J. 2015 Aug 4;34(15):2096-110. doi: 10.15252/embj.201488016. Epub 2015 Jun 16.

15.

Chromatin composition is changed by poly(ADP-ribosyl)ation during chromatin immunoprecipitation.

Beneke S, Meyer K, Holtz A, Hüttner K, Bürkle A.

PLoS One. 2012;7(3):e32914. doi: 10.1371/journal.pone.0032914. Epub 2012 Mar 30.

16.

BRCA1-dependent Chk1 phosphorylation triggers partial chromatin disassociation of phosphorylated Chk1 and facilitates S-phase cell cycle arrest.

Yarden RI, Metsuyanim S, Pickholtz I, Shabbeer S, Tellio H, Papa MZ.

Int J Biochem Cell Biol. 2012 Nov;44(11):1761-9. doi: 10.1016/j.biocel.2012.06.026. Epub 2012 Jun 26.

17.

Poly(ADP-ribose)-binding zinc finger motifs in DNA repair/checkpoint proteins.

Ahel I, Ahel D, Matsusaka T, Clark AJ, Pines J, Boulton SJ, West SC.

Nature. 2008 Jan 3;451(7174):81-5. doi: 10.1038/nature06420.

PMID:
18172500
18.

APE2 is required for ATR-Chk1 checkpoint activation in response to oxidative stress.

Willis J, Patel Y, Lentz BL, Yan S.

Proc Natl Acad Sci U S A. 2013 Jun 25;110(26):10592-7. doi: 10.1073/pnas.1301445110. Epub 2013 Jun 10.

19.

Poly(ADP-ribosyl)ation of Methyl CpG Binding Domain Protein 2 Regulates Chromatin Structure.

Becker A, Zhang P, Allmann L, Meilinger D, Bertulat B, Eck D, Hofstaetter M, Bartolomei G, Hottiger MO, Schreiber V, Leonhardt H, Cardoso MC.

J Biol Chem. 2016 Mar 4;291(10):4873-81. doi: 10.1074/jbc.M115.698357. Epub 2016 Jan 15. Erratum in: J Biol Chem. 2016 Apr 22;291(17):9382.

20.

Poly(ADP-ribosyl)ation as a new posttranslational modification of YB-1.

Alemasova EE, Pestryakov PE, Sukhanova MV, Kretov DA, Moor NA, Curmi PA, Ovchinnikov LP, Lavrik OI.

Biochimie. 2015 Dec;119:36-44. doi: 10.1016/j.biochi.2015.10.008. Epub 2015 Oct 9.

PMID:
26453809

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