Sort by
Items per page

Send to

Choose Destination

Links from PubMed

Items: 1 to 20 of 88


Alteration of mevalonate pathway related enzyme expressions in pressure overload-induced cardiac hypertrophy and associated heart failure with preserved ejection fraction.

Chen B, Zhong LY, Yang JX, Pan YY, Chen F, Yang J, Wu T, Hu SJ.

Cell Physiol Biochem. 2013;32(6):1761-75. doi: 10.1159/000356610. Epub 2013 Dec 13.


Mevalonate pathway is a novel target for hypertension.

Kishi T.

Circ J. 2011;75(6):1318-9. Epub 2011 Apr 29. No abstract available.


K(ATP) activation prevents progression of cardiac hypertrophy to failure induced by pressure overload via protecting endothelial function.

Gao S, Long CL, Wang RH, Wang H.

Cardiovasc Res. 2009 Aug 1;83(3):444-56. doi: 10.1093/cvr/cvp099. Epub 2009 Mar 20.


Alteration of mevalonate pathway in proliferated vascular smooth muscle from diabetic mice: possible role in high-glucose-induced atherogenic process.

Chen GP, Zhang XQ, Wu T, Li L, Han J, Du CQ.

J Diabetes Res. 2015;2015:379287. doi: 10.1155/2015/379287. Epub 2015 Mar 30.


Simvastatin inhibits cardiac hypertrophy and angiotensin-converting enzyme activity in rats with aortic stenosis.

Luo JD, Zhang WW, Zhang GP, Guan JX, Chen X.

Clin Exp Pharmacol Physiol. 1999 Nov;26(11):903-8.


Effect of farnesyltransferase inhibition on cardiac remodeling in spontaneously hypertensive rats.

Li X, Han J, Li L, Wang KJ, Hu SJ.

Int J Cardiol. 2013 Oct 9;168(4):3340-7. doi: 10.1016/j.ijcard.2013.04.038. Epub 2013 May 9.


Cardiac-specific overexpression of farnesyl pyrophosphate synthase induces cardiac hypertrophy and dysfunction in mice.

Yang J, Mou Y, Wu T, Ye Y, Jiang JC, Zhao CZ, Zhu HH, Du CQ, Zhou L, Hu SJ.

Cardiovasc Res. 2013 Mar 1;97(3):490-9. doi: 10.1093/cvr/cvs347. Epub 2012 Nov 24.


Concentric left ventricular remodeling in endothelial nitric oxide synthase knockout mice by chronic pressure overload.

Ruetten H, Dimmeler S, Gehring D, Ihling C, Zeiher AM.

Cardiovasc Res. 2005 Jun 1;66(3):444-53. Epub 2005 Feb 24.


G(13)-mediated signaling pathway is required for pressure overload-induced cardiac remodeling and heart failure.

Takefuji M, Wirth A, Lukasova M, Takefuji S, Boettger T, Braun T, Althoff T, Offermanns S, Wettschureck N.

Circulation. 2012 Oct 16;126(16):1972-82. doi: 10.1161/CIRCULATIONAHA.112.109256. Epub 2012 Sep 12.


Heart failure in pressure overload hypertrophy. The relative roles of ventricular remodeling and myocardial dysfunction.

Norton GR, Woodiwiss AJ, Gaasch WH, Mela T, Chung ES, Aurigemma GP, Meyer TE.

J Am Coll Cardiol. 2002 Feb 20;39(4):664-71.


Biochemical changes of mevalonate pathway in human colorectal cancer.

Caruso MG, Notarnicola M.

Anticancer Res. 2005 Sep-Oct;25(5):3393-7.


Angiotensin-converting enzyme inhibition prolongs survival and modifies the transition to heart failure in rats with pressure overload hypertrophy due to ascending aortic stenosis.

Weinberg EO, Schoen FJ, George D, Kagaya Y, Douglas PS, Litwin SE, Schunkert H, Benedict CR, Lorell BH.

Circulation. 1994 Sep;90(3):1410-22.


Hydroxymethylglutaryl coenzyme A reductase inhibitor simvastatin prevents cardiac hypertrophy induced by pressure overload and inhibits p21ras activation.

Indolfi C, Di Lorenzo E, Perrino C, Stingone AM, Curcio A, Torella D, Cittadini A, Cardone L, Coppola C, Cavuto L, Arcucci O, Sacca L, Avvedimento EV, Chiariello M.

Circulation. 2002 Oct 15;106(16):2118-24.


Alterations in protein kinase C isoenzyme expression and autophosphorylation during the progression of pressure overload-induced left ventricular hypertrophy.

Bayer AL, Heidkamp MC, Patel N, Porter M, Engman S, Samarel AM.

Mol Cell Biochem. 2003 Jan;242(1-2):145-52.


Decreased rates of substrate oxidation ex vivo predict the onset of heart failure and contractile dysfunction in rats with pressure overload.

Doenst T, Pytel G, Schrepper A, Amorim P, Färber G, Shingu Y, Mohr FW, Schwarzer M.

Cardiovasc Res. 2010 Jun 1;86(3):461-70. doi: 10.1093/cvr/cvp414. Epub 2009 Dec 24.


Ovariectomy augments pressure overload-induced hypertrophy associated with changes in Akt and nitric oxide synthase signaling pathways in female rats.

Bhuiyan MS, Shioda N, Fukunaga K.

Am J Physiol Endocrinol Metab. 2007 Dec;293(6):E1606-14. Epub 2007 Sep 18.


A high-fat diet increases adiposity but maintains mitochondrial oxidative enzymes without affecting development of heart failure with pressure overload.

Chess DJ, Khairallah RJ, O'Shea KM, Xu W, Stanley WC.

Am J Physiol Heart Circ Physiol. 2009 Nov;297(5):H1585-93. doi: 10.1152/ajpheart.00599.2009. Epub 2009 Sep 18.


Cardiac insulin-resistance and decreased mitochondrial energy production precede the development of systolic heart failure after pressure-overload hypertrophy.

Zhang L, Jaswal JS, Ussher JR, Sankaralingam S, Wagg C, Zaugg M, Lopaschuk GD.

Circ Heart Fail. 2013 Sep 1;6(5):1039-48. doi: 10.1161/CIRCHEARTFAILURE.112.000228. Epub 2013 Jul 16.

Supplemental Content

Support Center