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Exploring the determinants of trace amine-associated receptor 1's functional selectivity for the stereoisomers of amphetamine and methamphetamine.

Reese EA, Norimatsu Y, Grandy MS, Suchland KL, Bunzow JR, Grandy DK.

J Med Chem. 2014 Jan 23;57(2):378-90. doi: 10.1021/jm401316v. Epub 2014 Jan 7.


Trace amine-associated receptor 1 displays species-dependent stereoselectivity for isomers of methamphetamine, amphetamine, and para-hydroxyamphetamine.

Reese EA, Bunzow JR, Arttamangkul S, Sonders MS, Grandy DK.

J Pharmacol Exp Ther. 2007 Apr;321(1):178-86. Epub 2007 Jan 11.


Normal thermoregulatory responses to 3-iodothyronamine, trace amines and amphetamine-like psychostimulants in trace amine associated receptor 1 knockout mice.

Panas HN, Lynch LJ, Vallender EJ, Xie Z, Chen GL, Lynn SK, Scanlan TS, Miller GM.

J Neurosci Res. 2010 Jul;88(9):1962-9. doi: 10.1002/jnr.22367.


Methamphetamine and HIV-1-induced neurotoxicity: role of trace amine associated receptor 1 cAMP signaling in astrocytes.

Cisneros IE, Ghorpade A.

Neuropharmacology. 2014 Oct;85:499-507. doi: 10.1016/j.neuropharm.2014.06.011. Epub 2014 Jun 17.


Trace amine-associated receptor 1 is a stereoselective binding site for compounds in the amphetamine class.

Lewin AH, Miller GM, Gilmour B.

Bioorg Med Chem. 2011 Dec 1;19(23):7044-8. doi: 10.1016/j.bmc.2011.10.007. Epub 2011 Oct 13.


Rhesus monkey trace amine-associated receptor 1 signaling: enhancement by monoamine transporters and attenuation by the D2 autoreceptor in vitro.

Xie Z, Westmoreland SV, Bahn ME, Chen GL, Yang H, Vallender EJ, Yao WD, Madras BK, Miller GM.

J Pharmacol Exp Ther. 2007 Apr;321(1):116-27. Epub 2007 Jan 18.


Brain-specific overexpression of trace amine-associated receptor 1 alters monoaminergic neurotransmission and decreases sensitivity to amphetamine.

Revel FG, Meyer CA, Bradaia A, Jeanneau K, Calcagno E, André CB, Haenggi M, Miss MT, Galley G, Norcross RD, Invernizzi RW, Wettstein JG, Moreau JL, Hoener MC.

Neuropsychopharmacology. 2012 Nov;37(12):2580-92. doi: 10.1038/npp.2012.109. Epub 2012 Jul 4.


Trace Amine-Associated Receptor 1 Regulation of Methamphetamine Intake and Related Traits.

Harkness JH, Shi X, Janowsky A, Phillips TJ.

Neuropsychopharmacology. 2015 Aug;40(9):2175-84. doi: 10.1038/npp.2015.61. Epub 2015 Mar 5.


Insights into scFv:drug binding using the molecular dynamics simulation and free energy calculation.

Hu G, Zhang Q, Chen LY.

J Mol Model. 2011 Aug;17(8):1919-26. doi: 10.1007/s00894-010-0892-4. Epub 2010 Nov 26.


Differences between d-methamphetamine and d-amphetamine in rats: working memory, tolerance, and extinction.

Shoblock JR, Maisonneuve IM, Glick SD.

Psychopharmacology (Berl). 2003 Nov;170(2):150-6. Epub 2003 May 28.


Design, Synthesis, and Evaluation of Thyronamine Analogues as Novel Potent Mouse Trace Amine Associated Receptor 1 (mTAAR1) Agonists.

Chiellini G, Nesi G, Digiacomo M, Malvasi R, Espinoza S, Sabatini M, Frascarelli S, Laurino A, Cichero E, Macchia M, Gainetdinov RR, Fossa P, Raimondi L, Zucchi R, Rapposelli S.

J Med Chem. 2015 Jun 25;58(12):5096-107. doi: 10.1021/acs.jmedchem.5b00526. Epub 2015 Jun 5.


Trace amine-associated receptor 1 is a modulator of the dopamine transporter.

Xie Z, Miller GM.

J Pharmacol Exp Ther. 2007 Apr;321(1):128-36. Epub 2007 Jan 18.


Exploring the structure-activity relationship of the ethylamine portion of 3-iodothyronamine for rat and mouse trace amine-associated receptor 1.

Tan ES, Miyakawa M, Bunzow JR, Grandy DK, Scanlan TS.

J Med Chem. 2007 Jun 14;50(12):2787-98. Epub 2007 May 12.


Assessment of the N-oxidation of deprenyl, methamphetamine, and amphetamine enantiomers by chiral capillary electrophoresis: an in vitro metabolism study.

Szöko E, Tábi T, Borbás T, Dalmadi B, Tihanyi K, Magyar K.

Electrophoresis. 2004 Aug;25(16):2866-75.


A comparison of methylphenidate-, amphetamine-, and methamphetamine-induced hyperthermia and neurotoxicity in male Sprague-Dawley rats during the waking (lights off) cycle.

Levi MS, Divine B, Hanig JP, Doerge DR, Vanlandingham MM, George NI, Twaddle NC, Bowyer JF.

Neurotoxicol Teratol. 2012 Mar;34(2):253-62. doi: 10.1016/ Epub 2012 Jan 20.


A receptor mechanism for methamphetamine action in dopamine transporter regulation in brain.

Xie Z, Miller GM.

J Pharmacol Exp Ther. 2009 Jul;330(1):316-25. doi: 10.1124/jpet.109.153775. Epub 2009 Apr 13.


Human and mouse trace amine-associated receptor 1 have distinct pharmacology towards endogenous monoamines and imidazoline receptor ligands.

Hu LA, Zhou T, Ahn J, Wang S, Zhou J, Hu Y, Liu Q.

Biochem J. 2009 Oct 23;424(1):39-45. doi: 10.1042/BJ20090998.


Genetic Polymorphisms Affect Mouse and Human Trace Amine-Associated Receptor 1 Function.

Shi X, Walter NA, Harkness JH, Neve KA, Williams RW, Lu L, Belknap JK, Eshleman AJ, Phillips TJ, Janowsky A.

PLoS One. 2016 Mar 31;11(3):e0152581. doi: 10.1371/journal.pone.0152581. eCollection 2016.

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