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Items: 1 to 20 of 106

1.

Molecular effects of autoimmune-risk promoter polymorphisms on expression, exon choice, and translational efficiency of interferon regulatory factor 5.

Clark DN, Lambert JP, Till RE, Argueta LB, Greenhalgh KE, Henrie B, Bills T, Hawkley TF, Roznik MG, Sloan JM, Mayhew V, Woodland L, Nelson EP, Tsai MH, Poole BD.

J Interferon Cytokine Res. 2014 May;34(5):354-65. doi: 10.1089/jir.2012.0105. Epub 2013 Dec 18.

PMID:
24350899
2.

Comprehensive evaluation of the genetic variants of interferon regulatory factor 5 (IRF5) reveals a novel 5 bp length polymorphism as strong risk factor for systemic lupus erythematosus.

Sigurdsson S, Göring HH, Kristjansdottir G, Milani L, Nordmark G, Sandling JK, Eloranta ML, Feng D, Sangster-Guity N, Gunnarsson I, Svenungsson E, Sturfelt G, Jönsen A, Truedsson L, Barnes BJ, Alm G, Rönnblom L, Syvänen AC.

Hum Mol Genet. 2008 Mar 15;17(6):872-81. Epub 2007 Dec 6.

PMID:
18063667
3.

Structural insertion/deletion variation in IRF5 is associated with a risk haplotype and defines the precise IRF5 isoforms expressed in systemic lupus erythematosus.

Kozyrev SV, Lewén S, Reddy PM, Pons-Estel B; Argentine Collaborative Group, Witte T; German Collaborative Group, Junker P, Laustrup H, Gutiérrez C, Suárez A, Francisca González-Escribano M, Martín J; Spanish Collaborative Group, Alarcón-Riquelme ME.

Arthritis Rheum. 2007 Apr;56(4):1234-41.

4.

Interferon regulatory factor 5 gene polymorphism confers risk to several rheumatic diseases and correlates with expression of alternative thymic transcripts.

Nordang GB, Viken MK, Amundsen SS, Sanchez ES, Flatø B, Førre OT, Martin J, Kvien TK, Lie BA.

Rheumatology (Oxford). 2012 Apr;51(4):619-26. doi: 10.1093/rheumatology/ker364. Epub 2011 Dec 16.

PMID:
22179739
5.

Four Promoters of IRF5 Respond Distinctly to Stimuli and are Affected by Autoimmune-Risk Polymorphisms.

Clark DN, Read RD, Mayhew V, Petersen SC, Argueta LB, Stutz LA, Till RE, Bergsten SM, Robinson BS, Baumann DG, Heap JC, Poole BD.

Front Immunol. 2013 Nov 7;4:360. doi: 10.3389/fimmu.2013.00360. eCollection 2013.

6.

The CGGGG insertion/deletion polymorphism of the IRF5 promoter is a strong risk factor for primary Sjögren's syndrome.

Miceli-Richard C, Gestermann N, Ittah M, Comets E, Loiseau P, Puechal X, Hachulla E, Gottenberg JE, Lebon P, Becquemont L, Mariette X.

Arthritis Rheum. 2009 Jul;60(7):1991-7. doi: 10.1002/art.24662.

7.

Methylation profile of the promoter region of IRF5 in primary Sjögren's syndrome.

Gestermann N, Koutero M, Belkhir R, Tost J, Mariette X, Miceli-Richard C.

Eur Cytokine Netw. 2012 Oct-Dec;23(4):166-72. doi: 10.1684/ecn.2012.0316.

8.

A common haplotype of interferon regulatory factor 5 (IRF5) regulates splicing and expression and is associated with increased risk of systemic lupus erythematosus.

Graham RR, Kozyrev SV, Baechler EC, Reddy MV, Plenge RM, Bauer JW, Ortmann WA, Koeuth T, González Escribano MF; Argentine and Spanish Collaborative Groups, Pons-Estel B, Petri M, Daly M, Gregersen PK, Martín J, Altshuler D, Behrens TW, Alarcón-Riquelme ME.

Nat Genet. 2006 May;38(5):550-5. Epub 2006 Apr 16.

PMID:
16642019
9.

Genetic variants and disease-associated factors contribute to enhanced interferon regulatory factor 5 expression in blood cells of patients with systemic lupus erythematosus.

Feng D, Stone RC, Eloranta ML, Sangster-Guity N, Nordmark G, Sigurdsson S, Wang C, Alm G, Syvänen AC, Rönnblom L, Barnes BJ.

Arthritis Rheum. 2010 Feb;62(2):562-73. doi: 10.1002/art.27223.

10.

Association of an IRF5 gene functional polymorphism with Sjögren's syndrome.

Miceli-Richard C, Comets E, Loiseau P, Puechal X, Hachulla E, Mariette X.

Arthritis Rheum. 2007 Dec;56(12):3989-94.

11.

Promoter insertion/deletion in the IRF5 gene is highly associated with susceptibility to systemic lupus erythematosus in distinct populations, but exerts a modest effect on gene expression in peripheral blood mononuclear cells.

Löfgren SE, Yin H, Delgado-Vega AM, Sanchez E, Lewén S, Pons-Estel BA, Witte T, D'Alfonso S, Ortego-Centeno N, Martin J, Alarcón-Riquelme ME, Kozyrev SV.

J Rheumatol. 2010 Mar;37(3):574-8. doi: 10.3899/jrheum.090440. Epub 2010 Jan 15.

PMID:
20080916
12.

Interferon regulatory factor 5 (IRF5) gene variants are associated with multiple sclerosis in three distinct populations.

Kristjansdottir G, Sandling JK, Bonetti A, Roos IM, Milani L, Wang C, Gustafsdottir SM, Sigurdsson S, Lundmark A, Tienari PJ, Koivisto K, Elovaara I, Pirttilä T, Reunanen M, Peltonen L, Saarela J, Hillert J, Olsson T, Landegren U, Alcina A, Fernández O, Leyva L, Guerrero M, Lucas M, Izquierdo G, Matesanz F, Syvänen AC.

J Med Genet. 2008 Jun;45(6):362-9. doi: 10.1136/jmg.2007.055012. Epub 2008 Feb 19.

13.

Identification of three new cis-regulatory IRF5 polymorphisms: in vitro studies.

Alonso-Perez E, Fernandez-Poceiro R, Lalonde E, Kwan T, Calaza M, Gomez-Reino JJ, Majewski J, Gonzalez A.

Arthritis Res Ther. 2013 Aug 13;15(4):R82. doi: 10.1186/ar4262.

14.
15.

Analysis of IRF5 gene functional polymorphisms in rheumatoid arthritis.

Rueda B, Reddy MV, González-Gay MA, Balsa A, Pascual-Salcedo D, Petersson IF, Eimon A, Paira S, Scherbarth HR, Pons-Estel BA, González-Escribano MF, Alarcón-Riquelme ME, Martín J.

Arthritis Rheum. 2006 Dec;54(12):3815-9.

16.

Association of interferon regulatory factor 5 (IRF5) markers with an increased risk of lupus and overlapping autoimmunity in a Kuwaiti population.

AlFadhli S, Jahabani I.

Ann Hum Biol. 2014 Nov-Dec;41(6):531-9. doi: 10.3109/03014460.2014.899623. Epub 2014 Apr 3.

PMID:
24697591
17.

A redundant epistatic interaction between IRF5 and STAT4 of the type I interferon pathway in susceptibility to lupus and rheumatoid arthritis.

Kim K, Cho SK, Han TU, Kim JH, Kang SJ, Kang C, Bae SC.

Lupus. 2013 Nov;22(13):1336-40. doi: 10.1177/0961203313504479. Epub 2013 Sep 6.

PMID:
24014567
18.

A single nucleotide polymorphism in the IRF5 promoter region is associated with susceptibility to rheumatoid arthritis in the Japanese population.

Shimane K, Kochi Y, Yamada R, Okada Y, Suzuki A, Miyatake A, Kubo M, Nakamura Y, Yamamoto K.

Ann Rheum Dis. 2009 Mar;68(3):377-83. doi: 10.1136/ard.2007.085704. Epub 2008 Apr 13.

PMID:
18408250
19.

Association of a functional polymorphism in the IRF5 region with systemic sclerosis in a Japanese population.

Ito I, Kawaguchi Y, Kawasaki A, Hasegawa M, Ohashi J, Hikami K, Kawamoto M, Fujimoto M, Takehara K, Sato S, Hara M, Tsuchiya N.

Arthritis Rheum. 2009 Jun;60(6):1845-50. doi: 10.1002/art.24600.

20.

Association of polymorphisms in interferon regulatory factor 5 gene with rheumatoid arthritis: a metaanalysis.

Han SW, Lee WK, Kwon KT, Lee BK, Nam EJ, Kim GW.

J Rheumatol. 2009 Apr;36(4):693-7. doi: 10.3899/jrheum.081054. Epub 2009 Feb 17.

PMID:
19228650

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