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DNA methylation of IGF2DMR and H19 is associated with fetal and infant growth: the generation R study.

Bouwland-Both MI, van Mil NH, Stolk L, Eilers PH, Verbiest MM, Heijmans BT, Tiemeier H, Hofman A, Steegers EA, Jaddoe VW, Steegers-Theunissen RP.

PLoS One. 2013 Dec 12;8(12):e81731. doi: 10.1371/journal.pone.0081731. eCollection 2013.


Altered gene expression and methylation of the human chromosome 11 imprinted region in small for gestational age (SGA) placentae.

Guo L, Choufani S, Ferreira J, Smith A, Chitayat D, Shuman C, Uxa R, Keating S, Kingdom J, Weksberg R.

Dev Biol. 2008 Aug 1;320(1):79-91. doi: 10.1016/j.ydbio.2008.04.025. Epub 2008 Apr 27.


No evidence for copy number and methylation variation in H19 and KCNQ10T1 imprinting control regions in children born small for gestational age.

Murphy R, Thompson JM, Tost J, Mitchell EA; Auckland Birthweight Collaborative Study Group.

BMC Med Genet. 2014 Jun 17;15:67. doi: 10.1186/1471-2350-15-67.


Prenatal parental tobacco smoking, gene specific DNA methylation, and newborns size: the Generation R study.

Bouwland-Both MI, van Mil NH, Tolhoek CP, Stolk L, Eilers PH, Verbiest MM, Heijmans BT, Uitterlinden AG, Hofman A, van Ijzendoorn MH, Duijts L, de Jongste JC, Tiemeier H, Steegers EA, Jaddoe VW, Steegers-Theunissen RP.

Clin Epigenetics. 2015 Aug 11;7:83. doi: 10.1186/s13148-015-0115-z. eCollection 2015.


Epigenetic modulation of the IGF2/H19 imprinted domain in human embryonic and extra-embryonic compartments and its possible role in fetal growth restriction.

Tabano S, Colapietro P, Cetin I, Grati FR, Zanutto S, Mandò C, Antonazzo P, Pileri P, Rossella F, Larizza L, Sirchia SM, Miozzo M.

Epigenetics. 2010 May 16;5(4):313-24. Epub 2010 May 28.


IGF2 DNA methylation is a modulator of newborn's fetal growth and development.

St-Pierre J, Hivert MF, Perron P, Poirier P, Guay SP, Brisson D, Bouchard L.

Epigenetics. 2012 Oct;7(10):1125-32. doi: 10.4161/epi.21855. Epub 2012 Aug 21.


Determinants of maternal pregnancy one-carbon metabolism and newborn human DNA methylation profiles.

van Mil NH, Bouwland-Both MI, Stolk L, Verbiest MM, Hofman A, Jaddoe VW, Verhulst FC, Eilers PH, Uitterlinden AG, Steegers EA, Tiemeier H, Steegers-Theunissen RP.

Reproduction. 2014 Dec;148(6):581-92. doi: 10.1530/REP-14-0260.


Alterations in expression of imprinted genes from the H19/IGF2 loci in a multigenerational model of intrauterine growth restriction (IUGR).

Gonzalez-Rodriguez P, Cantu J, O'Neil D, Seferovic MD, Goodspeed DM, Suter MA, Aagaard KM.

Am J Obstet Gynecol. 2016 May;214(5):625.e1-625.e11. doi: 10.1016/j.ajog.2016.01.194. Epub 2016 Feb 12.


Methylation loss at H19 imprinted gene correlates with methylenetetrahydrofolate reductase gene promoter hypermethylation in semen samples from infertile males.

Rotondo JC, Selvatici R, Di Domenico M, Marci R, Vesce F, Tognon M, Martini F.

Epigenetics. 2013 Sep;8(9):990-7. doi: 10.4161/epi.25798. Epub 2013 Jul 24.


The impact of first trimester phthalate and phenol exposure on IGF2/H19 genomic imprinting and birth outcomes.

LaRocca J, Binder AM, McElrath TF, Michels KB.

Environ Res. 2014 Aug;133:396-406. doi: 10.1016/j.envres.2014.04.032. Epub 2014 Jun 25.


The effects of maternal anxiety during pregnancy on IGF2/H19 methylation in cord blood.

Mansell T, Novakovic B, Meyer B, Rzehak P, Vuillermin P, Ponsonby AL, Collier F, Burgner D, Saffery R, Ryan J; BIS investigator team.

Transl Psychiatry. 2016 Mar 29;6:e765. doi: 10.1038/tp.2016.32.


IGF-II expression and methylation in small for gestational age infants.

Zhang S, Zhai G, Wang J, Shi W, Zhang R, Chen C.

J Pediatr Endocrinol Metab. 2015 May;28(5-6):613-8. doi: 10.1515/jpem-2014-0269.


Analysis of imprinted IGF2/H19 gene methylation and expression in normal fertilized and parthenogenetic embryonic stem cells of pigs.

Uh KJ, Park CH, Choi KH, Park JK, Jeong YW, Roh S, Hyun SH, Shin T, Lee CK, Hwang WS.

Anim Reprod Sci. 2014 Jun 10;147(1-2):47-55. doi: 10.1016/j.anireprosci.2014.03.020. Epub 2014 Apr 12.


Epigenetic profiles in children with a neural tube defect; a case-control study in two populations.

Stolk L, Bouwland-Both MI, van Mil NH, Verbiest MM, Eilers PH, Zhu H, Suarez L, Uitterlinden AG, Steegers-Theunissen RP.

PLoS One. 2013 Nov 5;8(11):e78462. doi: 10.1371/journal.pone.0078462. eCollection 2013. Erratum in: PLoS One. 2014;9(1). doi:10.1371/annotation/930bd671-19cc-4846-8352-bf9cdf11d6c9. van Mill, Nina H [corrected to van Mil, Nina H].


DNA methylation of IGF2, GNASAS, INSIGF and LEP and being born small for gestational age.

Tobi EW, Heijmans BT, Kremer D, Putter H, Delemarre-van de Waal HA, Finken MJ, Wit JM, Slagboom PE.

Epigenetics. 2011 Feb;6(2):171-6. Epub 2011 Feb 1.


Exposure of pregnant mice to chlorpyrifos-methyl alters embryonic H19 gene methylation patterns.

Shin HS, Seo JH, Jeong SH, Park SW, Park Y, Son SW, Kim JS, Kang HG.

Environ Toxicol. 2014 Aug;29(8):926-35. doi: 10.1002/tox.21820. Epub 2012 Nov 2.


Alteration in Expression and Methylation of IGF2/H19 in Placenta and Umbilical Cord Blood Are Associated with Macrosomia Exposed to Intrauterine Hyperglycemia.

Su R, Wang C, Feng H, Lin L, Liu X, Wei Y, Yang H.

PLoS One. 2016 Feb 3;11(2):e0148399. doi: 10.1371/journal.pone.0148399. eCollection 2016.


Association of maternal and nutrient supply line factors with DNA methylation at the imprinted IGF2/H19 locus in multiple tissues of newborn twins.

Loke YJ, Galati JC, Morley R, Joo EJ, Novakovic B, Li X, Weinrich B, Carson N, Ollikainen M, Ng HK, Andronikos R, Aziz NK, Saffery R, Craig JM.

Epigenetics. 2013 Oct;8(10):1069-79. doi: 10.4161/epi.25908. Epub 2013 Aug 5.


Association of in vitro fertilization with global and IGF2/H19 methylation variation in newborn twins.

Loke YJ, Galati JC, Saffery R, Craig JM.

J Dev Orig Health Dis. 2015 Apr;6(2):115-24. doi: 10.1017/S2040174415000161.


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