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Items: 1 to 20 of 152

1.

Cartilage-specific overexpression of ERRγ results in Chondrodysplasia and reduced chondrocyte proliferation.

Cardelli M, Zirngibl RA, Boetto JF, McKenzie KP, Troy TC, Turksen K, Aubin JE.

PLoS One. 2013 Dec 9;8(12):e81511. doi: 10.1371/journal.pone.0081511. eCollection 2013.

2.

Reduced chondrocyte proliferation and chondrodysplasia in mice lacking the integrin-linked kinase in chondrocytes.

Terpstra L, Prud'homme J, Arabian A, Takeda S, Karsenty G, Dedhar S, St-Arnaud R.

J Cell Biol. 2003 Jul 7;162(1):139-48. Epub 2003 Jun 30.

4.

SHP2 regulates chondrocyte terminal differentiation, growth plate architecture and skeletal cell fates.

Bowen ME, Ayturk UM, Kurek KC, Yang W, Warman ML.

PLoS Genet. 2014 May 29;10(5):e1004364. doi: 10.1371/journal.pgen.1004364. eCollection 2014.

5.

Defective postnatal endochondral bone development by chondrocyte-specific targeted expression of parathyroid hormone type 2 receptor.

Panda DK, Goltzman D, Karaplis AC.

Am J Physiol Endocrinol Metab. 2012 Dec 15;303(12):E1489-501. doi: 10.1152/ajpendo.00254.2012. Epub 2012 Oct 23.

6.

Bone growth retardation in mouse embryos expressing human collagenase 1.

Imai K, Dalal SS, Hambor J, Mitchell P, Okada Y, Horton WC, D'Armiento J.

Am J Physiol Cell Physiol. 2007 Oct;293(4):C1209-15. Epub 2007 Jul 25.

7.

Cartilage-specific over-expression of CCN family member 2/connective tissue growth factor (CCN2/CTGF) stimulates insulin-like growth factor expression and bone growth.

Tomita N, Hattori T, Itoh S, Aoyama E, Yao M, Yamashiro T, Takigawa M.

PLoS One. 2013;8(3):e59226. doi: 10.1371/journal.pone.0059226. Epub 2013 Mar 28.

8.

Heparanase stimulates chondrogenesis and is up-regulated in human ectopic cartilage: a mechanism possibly involved in hereditary multiple exostoses.

Huegel J, Enomoto-Iwamoto M, Sgariglia F, Koyama E, Pacifici M.

Am J Pathol. 2015 Jun;185(6):1676-85. doi: 10.1016/j.ajpath.2015.02.014. Epub 2015 Apr 8.

9.

Chondrocyte-specific knockout of the G protein G(s)alpha leads to epiphyseal and growth plate abnormalities and ectopic chondrocyte formation.

Sakamoto A, Chen M, Kobayashi T, Kronenberg HM, Weinstein LS.

J Bone Miner Res. 2005 Apr;20(4):663-71. Epub 2004 Dec 6.

10.

Inhibition of beta-catenin signaling causes defects in postnatal cartilage development.

Chen M, Zhu M, Awad H, Li TF, Sheu TJ, Boyce BF, Chen D, O'Keefe RJ.

J Cell Sci. 2008 May 1;121(Pt 9):1455-65. doi: 10.1242/jcs.020362. Epub 2008 Apr 8.

11.

PTH receptor signaling in osteoblasts regulates endochondral vascularization in maintenance of postnatal growth plate.

Qiu T, Xian L, Crane J, Wen C, Hilton M, Lu W, Newman P, Cao X.

J Bone Miner Res. 2015 Feb;30(2):309-17. doi: 10.1002/jbmr.2327.

12.

Changes in type II procollagen isoform expression during chondrogenesis by disruption of an alternative 5' splice site within Col2a1 exon 2.

Hering TM, Wirthlin L, Ravindran S, McAlinden A.

Matrix Biol. 2014 Jun;36:51-63. doi: 10.1016/j.matbio.2014.04.004. Epub 2014 Apr 13.

13.

Signalling by fibroblast growth factor receptor 3 and parathyroid hormone-related peptide coordinate cartilage and bone development.

Amizuka N, Davidson D, Liu H, Valverde-Franco G, Chai S, Maeda T, Ozawa H, Hammond V, Ornitz DM, Goltzman D, Henderson JE.

Bone. 2004 Jan;34(1):13-25.

PMID:
14751559
14.

New insight on FGFR3-related chondrodysplasias molecular physiopathology revealed by human chondrocyte gene expression profiling.

Schibler L, Gibbs L, Benoist-Lasselin C, Decraene C, Martinovic J, Loget P, Delezoide AL, Gonzales M, Munnich A, Jais JP, Legeai-Mallet L.

PLoS One. 2009 Oct 29;4(10):e7633. doi: 10.1371/journal.pone.0007633.

15.

Histone deacetylase 7 (Hdac7) suppresses chondrocyte proliferation and β-catenin activity during endochondral ossification.

Bradley EW, Carpio LR, Olson EN, Westendorf JJ.

J Biol Chem. 2015 Jan 2;290(1):118-26. doi: 10.1074/jbc.M114.596247. Epub 2014 Nov 11.

16.

SOX9 is a major negative regulator of cartilage vascularization, bone marrow formation and endochondral ossification.

Hattori T, Müller C, Gebhard S, Bauer E, Pausch F, Schlund B, Bösl MR, Hess A, Surmann-Schmitt C, von der Mark H, de Crombrugghe B, von der Mark K.

Development. 2010 Mar;137(6):901-11. doi: 10.1242/dev.045203.

17.

Cartilage-specific ablation of XBP1 signaling in mouse results in a chondrodysplasia characterized by reduced chondrocyte proliferation and delayed cartilage maturation and mineralization.

Cameron TL, Gresshoff IL, Bell KM, Piróg KA, Sampurno L, Hartley CL, Sanford EM, Wilson R, Ermann J, Boot-Handford RP, Glimcher LH, Briggs MD, Bateman JF.

Osteoarthritis Cartilage. 2015 Apr;23(4):661-70. doi: 10.1016/j.joca.2015.01.001. Epub 2015 Jan 17.

18.

Chondrocyte-specific knockout of Cbfβ reveals the indispensable function of Cbfβ in chondrocyte maturation, growth plate development and trabecular bone formation in mice.

Wu M, Li YP, Zhu G, Lu Y, Wang Y, Jules J, McConnell M, Serra R, Shao JZ, Chen W.

Int J Biol Sci. 2014 Jul 29;10(8):861-72. doi: 10.7150/ijbs.8521. eCollection 2014.

19.

Dmp1-deficient mice display severe defects in cartilage formation responsible for a chondrodysplasia-like phenotype.

Ye L, Mishina Y, Chen D, Huang H, Dallas SL, Dallas MR, Sivakumar P, Kunieda T, Tsutsui TW, Boskey A, Bonewald LF, Feng JQ.

J Biol Chem. 2005 Feb 18;280(7):6197-203. Epub 2004 Dec 7.

20.

The transcription factor activating enhancer-binding protein epsilon (AP-2ε) regulates the core promoter of type II collagen (COL2A1).

Niebler S, Bosserhoff AK.

FEBS J. 2013 Mar;280(6):1397-408. doi: 10.1111/febs.12130. Epub 2013 Feb 11.

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