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Isp7 is a novel regulator of amino acid uptake in the TOR signaling pathway.

Laor D, Cohen A, Pasmanik-Chor M, Oron-Karni V, Kupiec M, Weisman R.

Mol Cell Biol. 2014 Mar;34(5):794-806. doi: 10.1128/MCB.01473-13. Epub 2013 Dec 16. Erratum in: Mol Cell Biol. 2014 Apr;34(8):1535.


Psk1, an AGC kinase family member in fission yeast, is directly phosphorylated and controlled by TORC1 and functions as S6 kinase.

Nakashima A, Otsubo Y, Yamashita A, Sato T, Yamamoto M, Tamanoi F.

J Cell Sci. 2012 Dec 1;125(Pt 23):5840-9. doi: 10.1242/jcs.111146. Epub 2012 Sep 12.


Fission yeast TORC1 regulates phosphorylation of ribosomal S6 proteins in response to nutrients and its activity is inhibited by rapamycin.

Nakashima A, Sato T, Tamanoi F.

J Cell Sci. 2010 Mar 1;123(Pt 5):777-86. doi: 10.1242/jcs.060319. Epub 2010 Feb 9.


TORC1 of fission yeast is rapamycin-sensitive.

Takahara T, Maeda T.

Genes Cells. 2012 Aug;17(8):698-708. doi: 10.1111/j.1365-2443.2012.01618.x. Epub 2012 Jul 5.


TORC1 Regulates Developmental Responses to Nitrogen Stress via Regulation of the GATA Transcription Factor Gaf1.

Laor D, Cohen A, Kupiec M, Weisman R.

MBio. 2015 Jul 7;6(4):e00959. doi: 10.1128/mBio.00959-15.


TORC1 signaling is governed by two negative regulators in fission yeast.

Ma N, Liu Q, Zhang L, Henske EP, Ma Y.

Genetics. 2013 Oct;195(2):457-68. doi: 10.1534/genetics.113.154674. Epub 2013 Aug 9.


Fission yeast Ryh1 GTPase activates TOR Complex 2 in response to glucose.

Hatano T, Morigasaki S, Tatebe H, Ikeda K, Shiozaki K.

Cell Cycle. 2015;14(6):848-56. doi: 10.1080/15384101.2014.1000215.


Phosphorylation of the amino-terminus of the AGC kinase Gad8 prevents its interaction with TORC2.

Du W, Forte GM, Smith D, Petersen J.

Open Biol. 2016 Mar;6(3). pii: 150189. doi: 10.1098/rsob.150189.


Rab-family GTPase regulates TOR complex 2 signaling in fission yeast.

Tatebe H, Morigasaki S, Murayama S, Zeng CT, Shiozaki K.

Curr Biol. 2010 Nov 23;20(22):1975-82. doi: 10.1016/j.cub.2010.10.026. Epub 2010 Oct 28.


TOR complex 2 controls gene silencing, telomere length maintenance, and survival under DNA-damaging conditions.

Schonbrun M, Laor D, López-Maury L, Bähler J, Kupiec M, Weisman R.

Mol Cell Biol. 2009 Aug;29(16):4584-94. doi: 10.1128/MCB.01879-08. Epub 2009 Jun 22.


Fission yeast TORC1 prevents eIF2α phosphorylation in response to nitrogen and amino acids via Gcn2 kinase.

Valbuena N, Rozalén AE, Moreno S.

J Cell Sci. 2012 Dec 15;125(Pt 24):5955-9. doi: 10.1242/jcs.105395. Epub 2012 Oct 29.


TORC1 signaling inhibition by rapamycin and caffeine affect lifespan, global gene expression, and cell proliferation of fission yeast.

Rallis C, Codlin S, Bähler J.

Aging Cell. 2013 Aug;12(4):563-73. doi: 10.1111/acel.12080. Epub 2013 May 2.


A role for TOR complex 2 signaling in promoting autophagy.

Vlahakis A, Powers T.

Autophagy. 2014;10(11):2085-6. doi: 10.4161/auto.36262.


Crosstalk between the Tor and Gcn2 pathways in response to different stresses.

Rødland GE, Tvegård T, Boye E, Grallert B.

Cell Cycle. 2014;13(3):453-61. doi: 10.4161/cc.27270. Epub 2013 Nov 26.


TORC2 is required to maintain genome stability during S phase in fission yeast.

Schonbrun M, Kolesnikov M, Kupiec M, Weisman R.

J Biol Chem. 2013 Jul 5;288(27):19649-60. doi: 10.1074/jbc.M113.464974. Epub 2013 May 23.


Phosphorylation of the TOR ATP binding domain by AGC kinase constitutes a novel mode of TOR inhibition.

Hálová L, Du W, Kirkham S, Smith DL, Petersen J.

J Cell Biol. 2013 Nov 25;203(4):595-604. doi: 10.1083/jcb.201305103. Epub 2013 Nov 18.


Nitrogen regulates AMPK to control TORC1 signaling.

Davie E, Forte GM, Petersen J.

Curr Biol. 2015 Feb 16;25(4):445-54. doi: 10.1016/j.cub.2014.12.034. Epub 2015 Jan 29.

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