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Items: 1 to 20 of 111

1.

Immunosuppression by N-methyl-D-aspartate receptor antagonists is mediated through inhibition of Kv1.3 and KCa3.1 channels in T cells.

Kahlfuß S, Simma N, Mankiewicz J, Bose T, Lowinus T, Klein-Hessling S, Sprengel R, Schraven B, Heine M, Bommhardt U.

Mol Cell Biol. 2014 Mar;34(5):820-31. doi: 10.1128/MCB.01273-13. Epub 2013 Dec 16.

2.

NMDA-receptor antagonists block B-cell function but foster IL-10 production in BCR/CD40-activated B cells.

Simma N, Bose T, Kahlfuss S, Mankiewicz J, Lowinus T, Lühder F, Schüler T, Schraven B, Heine M, Bommhardt U.

Cell Commun Signal. 2014 Dec 5;12:75. doi: 10.1186/s12964-014-0075-5.

3.

Expression of T-cell KV1.3 potassium channel correlates with pro-inflammatory cytokines and disease activity in ulcerative colitis.

Koch Hansen L, Sevelsted-Møller L, Rabjerg M, Larsen D, Hansen TP, Klinge L, Wulff H, Knudsen T, Kjeldsen J, Köhler R.

J Crohns Colitis. 2014 Nov;8(11):1378-91. doi: 10.1016/j.crohns.2014.04.003. Epub 2014 May 3.

4.

The anti-proliferative effect of cation channel blockers in T lymphocytes depends on the strength of mitogenic stimulation.

Petho Z, Balajthy A, Bartok A, Bene K, Somodi S, Szilagyi O, Rajnavolgyi E, Panyi G, Varga Z.

Immunol Lett. 2016 Mar;171:60-9. doi: 10.1016/j.imlet.2016.02.003. Epub 2016 Feb 6.

PMID:
26861999
5.

Potassium channel changes of peripheral blood T-lymphocytes from Kazakh hypertensive patients in Northwest China and the inhibition effect towards potassium channels by telmisartan.

Zhang Q, Gou F, Zhang Y, He Y, He J, Peng L, Cheng L, Yuan Q, Zhang G, Huang S.

Kardiol Pol. 2016;74(5):476-488. doi: 10.5603/KP.a2015.0210. Epub 2015 Oct 27.

6.

Selective inhibition of KCa3.1 channels mediates adenosine regulation of the motility of human T cells.

Chimote AA, Hajdu P, Kucher V, Boiko N, Kuras Z, Szilagyi O, Yun YH, Conforti L.

J Immunol. 2013 Dec 15;191(12):6273-80. doi: 10.4049/jimmunol.1300702. Epub 2013 Nov 13.

7.
8.

Blocking KCa3.1 channels increases tumor cell killing by a subpopulation of human natural killer lymphocytes.

Koshy S, Wu D, Hu X, Tajhya RB, Huq R, Khan FS, Pennington MW, Wulff H, Yotnda P, Beeton C.

PLoS One. 2013 Oct 11;8(10):e76740. doi: 10.1371/journal.pone.0076740. eCollection 2013.

9.

Blockage of K(Ca)3.1 and Kv1.3 channels of the B lymphocyte decreases the inflammatory monocyte chemotaxis.

Zhang S, Wang X, Ju C, Zhu L, Du Y, Gao C.

Int Immunopharmacol. 2016 Feb;31:266-71. doi: 10.1016/j.intimp.2015.12.032. Epub 2016 Feb 4.

PMID:
26795234
10.

The effects of Kv1.3 and IKCa1 potassium channel inhibition on calcium influx of human peripheral T lymphocytes in rheumatoid arthritis.

Toldi G, Bajnok A, Dobi D, Kaposi A, Kovács L, Vásárhelyi B, Balog A.

Immunobiology. 2013 Mar;218(3):311-6. doi: 10.1016/j.imbio.2012.05.013. Epub 2012 May 23.

PMID:
22705192
11.

Blocking KV1.3 channels inhibits Th2 lymphocyte function and treats a rat model of asthma.

Koshy S, Huq R, Tanner MR, Atik MA, Porter PC, Khan FS, Pennington MW, Hanania NA, Corry DB, Beeton C.

J Biol Chem. 2014 May 2;289(18):12623-32. doi: 10.1074/jbc.M113.517037. Epub 2014 Mar 18.

12.

Lovastatin blocks Kv1.3 channel in human T cells: a new mechanism to explain its immunomodulatory properties.

Zhao N, Dong Q, Qian C, Li S, Wu QF, Ding D, Li J, Wang BB, Guo KF, Xie JJ, Cheng X, Liao YH, Du YM.

Sci Rep. 2015 Nov 30;5:17381. doi: 10.1038/srep17381. Erratum in: Sci Rep. 2016;6:21655.

13.

The Ca²⁺-activated K⁺ channel KCa3.1 as a potential new target for the prevention of allograft vasculopathy.

Chen YJ, Lam J, Gregory CR, Schrepfer S, Wulff H.

PLoS One. 2013 Nov 29;8(11):e81006. doi: 10.1371/journal.pone.0081006. eCollection 2013.

14.

Activation of the KCa3.1 channel contributes to traumatic scratch injury-induced reactive astrogliosis through the JNK/c-Jun signaling pathway.

Yi M, Dou F, Lu Q, Yu Z, Chen H.

Neurosci Lett. 2016 Jun 15;624:62-71. doi: 10.1016/j.neulet.2016.05.004. Epub 2016 May 6.

PMID:
27163196
15.

Potassium channel-blockers as therapeutic agents to interfere with bone resorption of periodontal disease.

Valverde P, Kawai T, Taubman MA.

J Dent Res. 2005 Jun;84(6):488-99. Review.

PMID:
15914584
16.

Acacetin blocks kv1.3 channels and inhibits human T cell activation.

Zhao N, Dong Q, Fu XX, Du LL, Cheng X, Du YM, Liao YH.

Cell Physiol Biochem. 2014;34(4):1359-72. doi: 10.1159/000366343. Epub 2014 Oct 2.

17.

Characterization of the functional properties of the voltage-gated potassium channel Kv1.3 in human CD4+ T lymphocytes.

Hu L, Pennington M, Jiang Q, Whartenby KA, Calabresi PA.

J Immunol. 2007 Oct 1;179(7):4563-70.

18.

Clofazimine inhibits human Kv1.3 potassium channel by perturbing calcium oscillation in T lymphocytes.

Ren YR, Pan F, Parvez S, Fleig A, Chong CR, Xu J, Dang Y, Zhang J, Jiang H, Penner R, Liu JO.

PLoS One. 2008;3(12):e4009. doi: 10.1371/journal.pone.0004009. Epub 2008 Dec 23.

19.

T-lymphocyte calcium influx characteristics and their modulation by Kv1.3 and IKCa1 channel inhibitors in the neonate.

Toldi G, Treszl A, Pongor V, Gyarmati B, Tulassay T, Vásárhelyi B.

Int Immunol. 2010 Sep;22(9):769-74. doi: 10.1093/intimm/dxq063. Epub 2010 Jul 2.

PMID:
20601376
20.

Lymphocyte calcium influx characteristics and their modulation by Kv1.3 and IKCa1 channel inhibitors in healthy pregnancy and preeclampsia.

Toldi G, Stenczer B, Treszl A, Kollár S, Molvarec A, Tulassay T, Rigó J, Vásárhelyi B.

Am J Reprod Immunol. 2011 Feb;65(2):154-63. doi: 10.1111/j.1600-0897.2010.00899.x.

PMID:
20649894

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