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Items: 1 to 20 of 380

1.

Manipulation of cardiac phosphatidylinositol 3-kinase (PI3K)/Akt signaling by apoptosis regulator through modulating IAP expression (ARIA) regulates cardiomyocyte death during doxorubicin-induced cardiomyopathy.

Kitamura Y, Koide M, Akakabe Y, Matsuo K, Shimoda Y, Soma Y, Ogata T, Ueyama T, Matoba S, Yamada H, Ikeda K.

J Biol Chem. 2014 Jan 31;289(5):2788-800. doi: 10.1074/jbc.M113.508143. Epub 2013 Dec 13.

2.

Apoptosis regulator through modulating IAP expression (ARIA) controls the PI3K/Akt pathway in endothelial and endothelial progenitor cells.

Koide M, Ikeda K, Akakabe Y, Kitamura Y, Ueyama T, Matoba S, Yamada H, Okigaki M, Matsubara H.

Proc Natl Acad Sci U S A. 2011 Jun 7;108(23):9472-7. doi: 10.1073/pnas.1101296108. Epub 2011 May 18. Erratum in: Proc Natl Acad Sci U S A. 2015 May 5;112(18):E2411.

3.

Absence of thrombospondin-2 increases cardiomyocyte damage and matrix disruption in doxorubicin-induced cardiomyopathy.

van Almen GC, Swinnen M, Carai P, Verhesen W, Cleutjens JP, D'hooge J, Verheyen FK, Pinto YM, Schroen B, Carmeliet P, Heymans S.

J Mol Cell Cardiol. 2011 Sep;51(3):318-28. doi: 10.1016/j.yjmcc.2011.05.010. Epub 2011 May 23.

PMID:
21624372
4.

Erythropoietin protects against doxorubicin-induced cardiomyopathy via a phosphatidylinositol 3-kinase-dependent pathway.

Kim KH, Oudit GY, Backx PH.

J Pharmacol Exp Ther. 2008 Jan;324(1):160-9. Epub 2007 Oct 10.

5.

Heat shock protein 20 interacting with phosphorylated Akt reduces doxorubicin-triggered oxidative stress and cardiotoxicity.

Fan GC, Zhou X, Wang X, Song G, Qian J, Nicolaou P, Chen G, Ren X, Kranias EG.

Circ Res. 2008 Nov 21;103(11):1270-9. doi: 10.1161/CIRCRESAHA.108.182832. Epub 2008 Oct 23.

6.

Glycoprotein 130 regulates cardiac myocyte survival in doxorubicin-induced apoptosis through phosphatidylinositol 3-kinase/Akt phosphorylation and Bcl-xL/caspase-3 interaction.

Negoro S, Oh H, Tone E, Kunisada K, Fujio Y, Walsh K, Kishimoto T, Yamauchi-Takihara K.

Circulation. 2001 Jan 30;103(4):555-61.

7.

Neuregulin-1 protects against doxorubicin-induced apoptosis in cardiomyocytes through an Akt-dependent pathway.

An T, Zhang Y, Huang Y, Zhang R, Yin S, Guo X, Wang Y, Zou C, Wei B, Lv R, Zhou Q, Zhang J.

Physiol Res. 2013;62(4):379-85. Epub 2013 Apr 16.

8.

Aldehyde dehydrogenase 2 ameliorates doxorubicin-induced myocardial dysfunction through detoxification of 4-HNE and suppression of autophagy.

Sun A, Cheng Y, Zhang Y, Zhang Q, Wang S, Tian S, Zou Y, Hu K, Ren J, Ge J.

J Mol Cell Cardiol. 2014 Jun;71:92-104. doi: 10.1016/j.yjmcc.2014.01.002. Epub 2014 Jan 13.

PMID:
24434637
9.
10.

Loss of apoptosis regulator through modulating IAP expression (ARIA) protects blood vessels from atherosclerosis.

Matsuo K, Akakabe Y, Kitamura Y, Shimoda Y, Ono K, Ueyama T, Matoba S, Yamada H, Hatakeyama K, Asada Y, Emoto N, Ikeda K.

J Biol Chem. 2015 Feb 6;290(6):3784-92. doi: 10.1074/jbc.M114.605287. Epub 2014 Dec 22.

11.

Hemin decreases cardiac oxidative stress and fibrosis in a rat model of systemic hypertension via PI3K/Akt signalling.

Worou ME, Belmokhtar K, Bonnet P, Vourc'h P, Machet MC, Khamis G, Eder V.

Cardiovasc Res. 2011 Jul 15;91(2):320-9. doi: 10.1093/cvr/cvr072. Epub 2011 Mar 15.

PMID:
21406596
12.
13.

Focal adhesion kinase antagonizes doxorubicin cardiotoxicity via p21(Cip1.).

Cheng Z, DiMichele LA, Rojas M, Vaziri C, Mack CP, Taylor JM.

J Mol Cell Cardiol. 2014 Feb;67:1-11. doi: 10.1016/j.yjmcc.2013.12.002. Epub 2013 Dec 14.

14.

Anti-apoptotic effect of heat shock protein 90 on hypoxia-mediated cardiomyocyte damage is mediated via the phosphatidylinositol 3-kinase/AKT pathway.

Wang W, Peng Y, Wang Y, Zhao X, Yuan Z.

Clin Exp Pharmacol Physiol. 2009 Sep;36(9):899-903. doi: 10.1111/j.1440-1681.2009.05167.x. Epub 2009 Mar 2.

PMID:
19298537
15.

Hydrogen sulfide protects H9c2 cardiac cells against doxorubicin-induced cytotoxicity through the PI3K/Akt/FoxO3a pathway.

Liu MH, Zhang Y, He J, Tan TP, Wu SJ, Guo DM, He H, Peng J, Tang ZH, Jiang ZS.

Int J Mol Med. 2016 Jun;37(6):1661-8. doi: 10.3892/ijmm.2016.2563. Epub 2016 Apr 14.

PMID:
27081862
16.

Ghrelin inhibits doxorubicin cardiotoxicity by inhibiting excessive autophagy through AMPK and p38-MAPK.

Wang X, Wang XL, Chen HL, Wu D, Chen JX, Wang XX, Li RL, He JH, Mo L, Cen X, Wei YQ, Jiang W.

Biochem Pharmacol. 2014 Apr 1;88(3):334-50. doi: 10.1016/j.bcp.2014.01.040. Epub 2014 Feb 9.

PMID:
24522112
17.

Adiponectin protects against doxorubicin-induced cardiomyopathy by anti-apoptotic effects through AMPK up-regulation.

Konishi M, Haraguchi G, Ohigashi H, Ishihara T, Saito K, Nakano Y, Isobe M.

Cardiovasc Res. 2011 Feb 1;89(2):309-19. doi: 10.1093/cvr/cvq335. Epub 2010 Oct 25.

PMID:
20978005
18.

Association of PI3K-Akt signaling pathway with digitalis-induced hypertrophy of cardiac myocytes.

Liu L, Zhao X, Pierre SV, Askari A.

Am J Physiol Cell Physiol. 2007 Nov;293(5):C1489-97. Epub 2007 Aug 29.

19.

Panax notoginseng saponins inhibit ischemia-induced apoptosis by activating PI3K/Akt pathway in cardiomyocytes.

Chen S, Liu J, Liu X, Fu Y, Zhang M, Lin Q, Zhu J, Mai L, Shan Z, Yu X, Yang M, Lin S.

J Ethnopharmacol. 2011 Sep 1;137(1):263-70. doi: 10.1016/j.jep.2011.05.011. Epub 2011 May 17.

PMID:
21619920
20.

Activation of the bone morphogenetic protein receptor by H11kinase/Hsp22 promotes cardiac cell growth and survival.

Sui X, Li D, Qiu H, Gaussin V, Depre C.

Circ Res. 2009 Apr 10;104(7):887-95. doi: 10.1161/CIRCRESAHA.108.192328. Epub 2009 Feb 26.

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