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Protective effect of autophagy inhibition on ischemia-reperfusion-induced injury of N2a cells.

Wang ZQ, Yang Y, Lu T, Luo P, Li J, Wu JP, Tang ZZ, Lu QP, Duan QH.

J Huazhong Univ Sci Technolog Med Sci. 2013 Dec;33(6):810-816. doi: 10.1007/s11596-013-1203-y. Epub 2013 Dec 13.


Distinct roles of autophagy in the heart during ischemia and reperfusion: roles of AMP-activated protein kinase and Beclin 1 in mediating autophagy.

Matsui Y, Takagi H, Qu X, Abdellatif M, Sakoda H, Asano T, Levine B, Sadoshima J.

Circ Res. 2007 Mar 30;100(6):914-22. Epub 2007 Mar 1.


Beclin-1-mediated autophagy protects spinal cord neurons against mechanical injury-induced apoptosis.

Wang ZY, Lin JH, Muharram A, Liu WG.

Apoptosis. 2014 Jun;19(6):933-45. doi: 10.1007/s10495-014-0976-1.


Puquitinib mesylate (XC-302) induces autophagy via inhibiting the PI3K/AKT/mTOR signaling pathway in nasopharyngeal cancer cells.

Wang KF, Yang H, Jiang WQ, Li S, Cai YC.

Int J Mol Med. 2015 Dec;36(6):1556-62. doi: 10.3892/ijmm.2015.2378. Epub 2015 Oct 16.


Choline Inhibits Ischemia-Reperfusion-Induced Cardiomyocyte Autophagy in Rat Myocardium by Activating Akt/mTOR Signaling.

Hang P, Zhao J, Su Z, Sun H, Chen T, Zhao L, Du Z.

Cell Physiol Biochem. 2018;45(5):2136-2144. doi: 10.1159/000488049. Epub 2018 Mar 7.


Rapamycin induces of protective autophagy in vascular endothelial cells exposed to oxygen-glucose deprivation.

Urbanek T, Kuczmik W, Basta-Kaim A, Gabryel B.

Brain Res. 2014 Mar 17;1553:1-11. doi: 10.1016/j.brainres.2014.01.017. Epub 2014 Jan 22.


Endoplasmic reticulum stress sensitizes human esophageal cancer cell to radiation.

Pang XL, He G, Liu YB, Wang Y, Zhang B.

World J Gastroenterol. 2013 Mar 21;19(11):1736-48. doi: 10.3748/wjg.v19.i11.1736.


Activation of autophagy and Akt/CREB signaling play an equivalent role in the neuroprotective effect of rapamycin in neonatal hypoxia-ischemia.

Carloni S, Girelli S, Scopa C, Buonocore G, Longini M, Balduini W.

Autophagy. 2010 Apr;6(3):366-77. Epub 2010 Apr 20.


Melatonin inhibits mTOR-dependent autophagy during liver ischemia/reperfusion.

Kang JW, Cho HI, Lee SM.

Cell Physiol Biochem. 2014;33(1):23-36. doi: 10.1159/000356647. Epub 2014 Jan 2.


Regulation on Beclin-1 expression by mTOR in CoCl2-induced HT22 cell ischemia-reperfusion injury.

Yang T, Li D, Liu F, Qi L, Yan G, Wang M.

Brain Res. 2015 Jul 21;1614:60-6. doi: 10.1016/j.brainres.2015.04.016. Epub 2015 Apr 18.


Autophagy and mTORC1 regulate the stochastic phase of somatic cell reprogramming.

Wu Y, Li Y, Zhang H, Huang Y, Zhao P, Tang Y, Qiu X, Ying Y, Li W, Ni S, Zhang M, Liu L, Xu Y, Zhuang Q, Luo Z, Benda C, Song H, Liu B, Lai L, Liu X, Tse HF, Bao X, Chan WY, Esteban MA, Qin B, Pei D.

Nat Cell Biol. 2015 Jun;17(6):715-25. doi: 10.1038/ncb3172. Epub 2015 May 18.


Propofol prevents autophagic cell death following oxygen and glucose deprivation in PC12 cells and cerebral ischemia-reperfusion injury in rats.

Cui D, Wang L, Qi A, Zhou Q, Zhang X, Jiang W.

PLoS One. 2012;7(4):e35324. doi: 10.1371/journal.pone.0035324. Epub 2012 Apr 11.


Increased expression of Beclin-1-dependent autophagy protects against beta-amyloid-induced cell injury in PC12 cells [corrected].

Xue Z, Zhang S, Huang L, He Y, Fang R, Fang Y.

J Mol Neurosci. 2013 Sep;51(1):180-6. doi: 10.1007/s12031-013-9974-y. Epub 2013 Feb 19. Erratum in: J Mol Neurosci. 2013 Oct;51(2):636.


Rapamycin protection of livers from ischemia and reperfusion injury is dependent on both autophagy induction and mammalian target of rapamycin complex 2-Akt activation.

Zhu J, Lu T, Yue S, Shen X, Gao F, Busuttil RW, Kupiec-Weglinski JW, Xia Q, Zhai Y.

Transplantation. 2015 Jan;99(1):48-55. doi: 10.1097/TP.0000000000000476.


A combination of four active compounds alleviates cerebral ischemia-reperfusion injury in correlation with inhibition of autophagy and modulation of AMPK/mTOR and JNK pathways.

Guo Z, Cao G, Yang H, Zhou H, Li L, Cao Z, Yu B, Kou J.

J Neurosci Res. 2014 Oct;92(10):1295-306. doi: 10.1002/jnr.23400. Epub 2014 May 7.


Global ischemia induces lysosomal-mediated degradation of mTOR and activation of autophagy in hippocampal neurons destined to die.

Hwang JY, Gertner M, Pontarelli F, Court-Vazquez B, Bennett MV, Ofengeim D, Zukin RS.

Cell Death Differ. 2017 Feb;24(2):317-329. doi: 10.1038/cdd.2016.140. Epub 2016 Dec 9.


SIRT1 positively regulates autophagy and mitochondria function in embryonic stem cells under oxidative stress.

Ou X, Lee MR, Huang X, Messina-Graham S, Broxmeyer HE.

Stem Cells. 2014 May;32(5):1183-94. doi: 10.1002/stem.1641.


Electroacupuncture protects against ischemic stroke by reducing autophagosome formation and inhibiting autophagy through the mTORC1-ULK1 complex-Beclin1 pathway.

Liu W, Shang G, Yang S, Huang J, Xue X, Lin Y, Zheng Y, Wang X, Wang L, Lin R, Tao J, Chen L.

Int J Mol Med. 2016 Feb;37(2):309-18. doi: 10.3892/ijmm.2015.2425. Epub 2015 Dec 7.


Ischemic preconditioning enhances autophagy but suppresses autophagic cell death in rat spinal neurons following ischemia-reperfusion.

Fan J, Zhang Z, Chao X, Gu J, Cai W, Zhou W, Yin G, Li Q.

Brain Res. 2014 May 8;1562:76-86. doi: 10.1016/j.brainres.2014.03.019. Epub 2014 Mar 25.


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