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Items: 1 to 20 of 263

1.

Suppression of VEGF expression through interruption of the HIF‑1α and Akt signaling cascade modulates the anti‑angiogenic activity of DAPK in ovarian carcinoma cells.

Park ST, Kim BR, Park SH, Lee JH, Lee EJ, Lee SH, Rho SB.

Oncol Rep. 2014 Feb;31(2):1021-9. doi: 10.3892/or.2013.2928. Epub 2013 Dec 16.

PMID:
24337450
2.

GABARBP down-regulates HIF-1α expression through the VEGFR-2 and PI3K/mTOR/4E-BP1 pathways.

Park SH, Kim BR, Lee JH, Park ST, Lee SH, Dong SM, Rho SB.

Cell Signal. 2014 Jul;26(7):1506-13. doi: 10.1016/j.cellsig.2014.03.017. Epub 2014 Mar 29.

PMID:
24686084
3.

MARCKSL1 exhibits anti-angiogenic effects through suppression of VEGFR-2-dependent Akt/PDK-1/mTOR phosphorylation.

Kim BR, Lee SH, Park MS, Seo SH, Park YM, Kwon YJ, Rho SB.

Oncol Rep. 2016 Feb;35(2):1041-8. doi: 10.3892/or.2015.4408. Epub 2015 Nov 10.

PMID:
26555156
4.

sMEK1 inhibits endothelial cell proliferation by attenuating VEGFR-2-dependent-Akt/eNOS/HIF-1α signaling pathways.

Kim BR, Seo SH, Park MS, Lee SH, Kwon Y, Rho SB.

Oncotarget. 2015 Oct 13;6(31):31830-43. doi: 10.18632/oncotarget.5570.

5.

Magnolol suppresses hypoxia-induced angiogenesis via inhibition of HIF-1α/VEGF signaling pathway in human bladder cancer cells.

Chen MC, Lee CF, Huang WH, Chou TC.

Biochem Pharmacol. 2013 May 1;85(9):1278-87. doi: 10.1016/j.bcp.2013.02.009. Epub 2013 Feb 14.

PMID:
23416116
7.
8.
9.

Downregulation of ERRα inhibits angiogenesis in human umbilical vein endothelial cells through regulating VEGF production and PI3K/Akt/STAT3 signaling pathway.

Zhang LD, Chen L, Zhang M, Qi HJ, Chen L, Chen HF, Zhong MK, Shi XJ, Li QY.

Eur J Pharmacol. 2015 Dec 15;769:167-76. doi: 10.1016/j.ejphar.2015.11.014. Epub 2015 Nov 14.

PMID:
26586335
10.

Topotecan inhibits vascular endothelial growth factor production and angiogenic activity induced by hypoxia in human neuroblastoma by targeting hypoxia-inducible factor-1alpha and -2alpha.

Puppo M, Battaglia F, Ottaviano C, Delfino S, Ribatti D, Varesio L, Bosco MC.

Mol Cancer Ther. 2008 Jul;7(7):1974-84. doi: 10.1158/1535-7163.MCT-07-2059.

11.

Delphinidin inhibits angiogenesis through the suppression of HIF-1α and VEGF expression in A549 lung cancer cells.

Kim MH, Jeong YJ, Cho HJ, Hoe HS, Park KK, Park YY, Choi YH, Kim CH, Chang HW, Park YJ, Chung IK, Chang YC.

Oncol Rep. 2017 Feb;37(2):777-784. doi: 10.3892/or.2016.5296. Epub 2016 Dec 7.

PMID:
27959445
13.

Benzyl isothiocyanate suppresses pancreatic tumor angiogenesis and invasion by inhibiting HIF-α/VEGF/Rho-GTPases: pivotal role of STAT-3.

Boreddy SR, Sahu RP, Srivastava SK.

PLoS One. 2011;6(10):e25799. doi: 10.1371/journal.pone.0025799. Epub 2011 Oct 10.

14.

Loss of Mel-18 induces tumor angiogenesis through enhancing the activity and expression of HIF-1α mediated by the PTEN/PI3K/Akt pathway.

Park JH, Lee JY, Shin DH, Jang KS, Kim HJ, Kong G.

Oncogene. 2011 Nov 10;30(45):4578-89. doi: 10.1038/onc.2011.174. Epub 2011 May 23.

PMID:
21602890
15.

Dickkopf-3 (DKK-3) obstructs VEGFR-2/Akt/mTOR signaling cascade by interacting of β2-microglobulin (β2M) in ovarian tumorigenesis.

Kim BR, Lee EJ, Seo SH, Lee SH, Rho SB.

Cell Signal. 2015 Nov;27(11):2150-9. doi: 10.1016/j.cellsig.2015.08.008. Epub 2015 Aug 14.

PMID:
26278164
16.

Hypoxia-inducible factor 1alpha and antiangiogenic activity of farnesyltransferase inhibitor SCH66336 in human aerodigestive tract cancer.

Han JY, Oh SH, Morgillo F, Myers JN, Kim E, Hong WK, Lee HY.

J Natl Cancer Inst. 2005 Sep 7;97(17):1272-86. Erratum in: J Natl Cancer Inst. 2007 Aug 1;99(15):1211.

PMID:
16145048
17.

Retinoblastoma binding protein 2 (RBP2) promotes HIF-1α-VEGF-induced angiogenesis of non-small cell lung cancer via the Akt pathway.

Qi L, Zhu F, Li SH, Si LB, Hu LK, Tian H.

PLoS One. 2014 Aug 27;9(8):e106032. doi: 10.1371/journal.pone.0106032. eCollection 2014.

18.

A novel inhibitor of hypoxia-inducible factor-1α P3155 also modulates PI3K pathway and inhibits growth of prostate cancer cells.

Manohar SM, Padgaonkar AA, Jalota-Badhwar A, Sonawane V, Rathos MJ, Kumar S, Joshi KS.

BMC Cancer. 2011 Aug 5;11:338. doi: 10.1186/1471-2407-11-338.

19.

Fasudil-induced hypoxia-inducible factor-1alpha degradation disrupts a hypoxia-driven vascular endothelial growth factor autocrine mechanism in endothelial cells.

Takata K, Morishige K, Takahashi T, Hashimoto K, Tsutsumi S, Yin L, Ohta T, Kawagoe J, Takahashi K, Kurachi H.

Mol Cancer Ther. 2008 Jun;7(6):1551-61. doi: 10.1158/1535-7163.MCT-07-0428.

20.

Role of PI3K/Akt and MEK/ERK in mediating hypoxia-induced expression of HIF-1alpha and VEGF in laser-induced rat choroidal neovascularization.

Yang XM, Wang YS, Zhang J, Li Y, Xu JF, Zhu J, Zhao W, Chu DK, Wiedemann P.

Invest Ophthalmol Vis Sci. 2009 Apr;50(4):1873-9. doi: 10.1167/iovs.08-2591. Epub 2008 Dec 20.

PMID:
19098317

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