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Items: 1 to 20 of 131

1.

[Preclinical research. Seal of approval translational medicine].

Hermann S, Pichler B, Kotzerke J.

Nuklearmedizin. 2013 Dec 13;52(6):N53-4. German. No abstract available.

PMID:
24337015
2.

Preclinical research: Design animal studies better.

Macleod MR.

Nature. 2014 Jun 5;510(7503):35. doi: 10.1038/510035a. No abstract available.

PMID:
24899295
3.

Animal models: Mouse already being charted gene by gene.

Brown S.

Nature. 2014 Apr 17;508(7496):319. doi: 10.1038/508319d. No abstract available.

PMID:
24740057
4.

Preclinical research: Make mouse studies work.

Perrin S.

Nature. 2014 Mar 27;507(7493):423-5. No abstract available.

PMID:
24678540
5.

Reverse translation of failed treatments can help improving the validity of preclinical animal models.

't Hart BA.

Eur J Pharmacol. 2015 Jul 15;759:14-8. doi: 10.1016/j.ejphar.2015.03.030. Epub 2015 Mar 28. Review.

PMID:
25823810
6.

Preclinical studies of human disease: time to take methodological quality seriously.

van der Worp HB, Macleod MR.

J Mol Cell Cardiol. 2011 Oct;51(4):449-50. doi: 10.1016/j.yjmcc.2011.04.008. Epub 2011 Apr 29. No abstract available.

PMID:
21549125
7.

Radiopharmaceutical space.

Eckelman WC, Kilbourn MR, Mathis CA.

Nucl Med Biol. 2006 Oct;33(7):829. No abstract available.

PMID:
17045161
8.

Science translational medicine issue.

Schwaiger M.

Q J Nucl Med Mol Imaging. 2016 Sep;60(3):183-4. No abstract available.

9.

Paediatric diagnostic reference levels in nuclear medicine imaging in Ireland.

Gray L, Torreggiani W, O'Reilly G.

Br J Radiol. 2008 Nov;81(971):918-9. doi: 10.1259/bjr/22537486. No abstract available.

PMID:
18941051
10.

Tackling reproducibility in academic preclinical drug discovery.

Frye SV, Arkin MR, Arrowsmith CH, Conn PJ, Glicksman MA, Hull-Ryde EA, Slusher BS.

Nat Rev Drug Discov. 2015 Nov;14(11):733-4. doi: 10.1038/nrd4737. Epub 2015 Sep 21.

PMID:
26388229
11.

The marmoset monkey: a multi-purpose preclinical and translational model of human biology and disease.

't Hart BA, Abbott DH, Nakamura K, Fuchs E.

Drug Discov Today. 2012 Nov;17(21-22):1160-5. doi: 10.1016/j.drudis.2012.06.009. Epub 2012 Jun 21.

PMID:
22728226
12.

A defining moment: Nuclear medicine, molecular imaging, SNM.

Sandler MP.

J Nucl Med. 2006 Jul;47(7):36N, 37N. No abstract available.

13.

Preface to the special issue "Novel pharmaconeurogenetic approaches arising from progress in translational genetics".

Renger JJ, Kern JT.

J Neurogenet. 2011 Dec;25(4):117-9. doi: 10.3109/01677063.2011.629355. Epub 2011 Nov 10. No abstract available.

PMID:
22074379
14.

The safety, efficacy and regulatory triangle in drug development: Impact for animal models and the use of animals.

van Meer PJ, Graham ML, Schuurman HJ.

Eur J Pharmacol. 2015 Jul 15;759:3-13. doi: 10.1016/j.ejphar.2015.02.055. Epub 2015 Mar 27. Review.

PMID:
25818943
15.

Identification of new epilepsy treatments: issues in preclinical methodology.

Galanopoulou AS, Buckmaster PS, Staley KJ, Moshé SL, Perucca E, Engel J Jr, Löscher W, Noebels JL, Pitkänen A, Stables J, White HS, O'Brien TJ, Simonato M; American Epilepsy Society Basic Science Committee And The International League Against Epilepsy Working Group On Recommendations For Preclinical Epilepsy Drug Discovery.

Epilepsia. 2012 Mar;53(3):571-82. doi: 10.1111/j.1528-1167.2011.03391.x. Epub 2012 Jan 31. Review.

16.

Why clinical translation cannot succeed without failure.

London AJ, Kimmelman J.

Elife. 2015 Nov 24;4:e12844. doi: 10.7554/eLife.12844.

17.

Cardiovascular pharmacotherapy: Innovation stuck in translation.

Rongen GA, Wever KE.

Eur J Pharmacol. 2015 Jul 15;759:200-4. doi: 10.1016/j.ejphar.2015.03.035. Epub 2015 Mar 24. Review.

PMID:
25814253
18.

The next step in translational research: lessons learned from the first preclinical randomized controlled trial.

Llovera G, Liesz A.

J Neurochem. 2016 Oct;139 Suppl 2:271-279. doi: 10.1111/jnc.13516. Epub 2016 Mar 10. Review.

PMID:
26968835
19.

Instrumentation and radiopharmaceutical validation.

Zigler SS.

Q J Nucl Med Mol Imaging. 2009 Aug;53(4):402-10.

20.

Data acquisition and analysis: the strength of methodology in nuclear medicine and molecular imaging.

Lucignani G.

Eur J Nucl Med Mol Imaging. 2006 Dec;33(12):1513-6. Review. No abstract available.

PMID:
17072612

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