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Items: 1 to 20 of 144


Wnt5a uses CD146 as a receptor to regulate cell motility and convergent extension.

Ye Z, Zhang C, Tu T, Sun M, Liu D, Lu D, Feng J, Yang D, Liu F, Yan X.

Nat Commun. 2013;4:2803. doi: 10.1038/ncomms3803.


Rab35 is required for Wnt5a/Dvl2-induced Rac1 activation and cell migration in MCF-7 breast cancer cells.

Zhu Y, Shen T, Liu J, Zheng J, Zhang Y, Xu R, Sun C, Du J, Chen Y, Gu L.

Cell Signal. 2013 May;25(5):1075-85. doi: 10.1016/j.cellsig.2013.01.015. Epub 2013 Jan 24.


Dvl2-dependent activation of Daam1 and RhoA regulates Wnt5a-induced breast cancer cell migration.

Zhu Y, Tian Y, Du J, Hu Z, Yang L, Liu J, Gu L.

PLoS One. 2012;7(5):e37823. doi: 10.1371/journal.pone.0037823. Epub 2012 May 24.


Casein kinase Iepsilon modulates the signaling specificities of dishevelled.

Cong F, Schweizer L, Varmus H.

Mol Cell Biol. 2004 Mar;24(5):2000-11.


Dissection of Wnt5a-Ror2 signaling leading to matrix metalloproteinase (MMP-13) expression.

Yamagata K, Li X, Ikegaki S, Oneyama C, Okada M, Nishita M, Minami Y.

J Biol Chem. 2012 Jan 6;287(2):1588-99. doi: 10.1074/jbc.M111.315127. Epub 2011 Nov 28.


Ror2 receptor mediates Wnt11 ligand signaling and affects convergence and extension movements in zebrafish.

Bai Y, Tan X, Zhang H, Liu C, Zhao B, Li Y, Lu L, Liu Y, Zhou J.

J Biol Chem. 2014 Jul 25;289(30):20664-76.


The prickle-related gene in vertebrates is essential for gastrulation cell movements.

Takeuchi M, Nakabayashi J, Sakaguchi T, Yamamoto TS, Takahashi H, Takeda H, Ueno N.

Curr Biol. 2003 Apr 15;13(8):674-9.


Ror2/Frizzled complex mediates Wnt5a-induced AP-1 activation by regulating Dishevelled polymerization.

Nishita M, Itsukushima S, Nomachi A, Endo M, Wang Z, Inaba D, Qiao S, Takada S, Kikuchi A, Minami Y.

Mol Cell Biol. 2010 Jul;30(14):3610-9. doi: 10.1128/MCB.00177-10. Epub 2010 May 10.


Jun NH2-terminal kinase (JNK) prevents nuclear beta-catenin accumulation and regulates axis formation in Xenopus embryos.

Liao G, Tao Q, Kofron M, Chen JS, Schloemer A, Davis RJ, Hsieh JC, Wylie C, Heasman J, Kuan CY.

Proc Natl Acad Sci U S A. 2006 Oct 31;103(44):16313-8. Epub 2006 Oct 23.


C-Jun N-terminal kinase (JNK) mediates Wnt5a-induced cell motility dependent or independent of RhoA pathway in human dental papilla cells.

Wang C, Zhao Y, Su Y, Li R, Lin Y, Zhou X, Ye L.

PLoS One. 2013 Jul 3;8(7):e69440. doi: 10.1371/journal.pone.0069440. Print 2013.


The Dishevelled-associating protein Daple controls the non-canonical Wnt/Rac pathway and cell motility.

Ishida-Takagishi M, Enomoto A, Asai N, Ushida K, Watanabe T, Hashimoto T, Kato T, Weng L, Matsumoto S, Asai M, Murakumo Y, Kaibuchi K, Kikuchi A, Takahashi M.

Nat Commun. 2012 May 29;3:859. doi: 10.1038/ncomms1861.


HECT domain-containing E3 ubiquitin ligase NEDD4L negatively regulates Wnt signaling by targeting dishevelled for proteasomal degradation.

Ding Y, Zhang Y, Xu C, Tao QH, Chen YG.

J Biol Chem. 2013 Mar 22;288(12):8289-98. doi: 10.1074/jbc.M112.433185. Epub 2013 Feb 9.


Wnt5a signaling controls cytokinesis by correctly positioning ESCRT-III at the midbody.

Fumoto K, Kikuchi K, Gon H, Kikuchi A.

J Cell Sci. 2012 Oct 15;125(Pt 20):4822-32. doi: 10.1242/jcs.108142. Epub 2012 Jul 23.


Wnt proteins induce dishevelled phosphorylation via an LRP5/6- independent mechanism, irrespective of their ability to stabilize beta-catenin.

González-Sancho JM, Brennan KR, Castelo-Soccio LA, Brown AM.

Mol Cell Biol. 2004 Jun;24(11):4757-68.


The Meckel-Gruber syndrome protein TMEM67 controls basal body positioning and epithelial branching morphogenesis in mice via the non-canonical Wnt pathway.

Abdelhamed ZA, Natarajan S, Wheway G, Inglehearn CF, Toomes C, Johnson CA, Jagger DJ.

Dis Model Mech. 2015 Jun;8(6):527-41. doi: 10.1242/dmm.019083. Epub 2015 Apr 7.


Wnt5a signaling induces proliferation and survival of endothelial cells in vitro and expression of MMP-1 and Tie-2.

Masckauchán TN, Agalliu D, Vorontchikhina M, Ahn A, Parmalee NL, Li CM, Khoo A, Tycko B, Brown AM, Kitajewski J.

Mol Biol Cell. 2006 Dec;17(12):5163-72. Epub 2006 Oct 11.


NEDD4L regulates convergent extension movements in Xenopus embryos via Disheveled-mediated non-canonical Wnt signaling.

Zhang Y, Ding Y, Chen YG, Tao Q.

Dev Biol. 2014 Aug 1;392(1):15-25. doi: 10.1016/j.ydbio.2014.05.003. Epub 2014 May 14.


Filopodia formation mediated by receptor tyrosine kinase Ror2 is required for Wnt5a-induced cell migration.

Nishita M, Yoo SK, Nomachi A, Kani S, Sougawa N, Ohta Y, Takada S, Kikuchi A, Minami Y.

J Cell Biol. 2006 Nov 20;175(4):555-62. Epub 2006 Nov 13.

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