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Items: 1 to 20 of 95

1.

DNA methyltransferase inhibition reverses epigenetically embedded phenotypes in lung cancer preferentially affecting polycomb target genes.

Hascher A, Haase AK, Hebestreit K, Rohde C, Klein HU, Rius M, Jungen D, Witten A, Stoll M, Schulze I, Ogawa S, Wiewrodt R, Tickenbrock L, Berdel WE, Dugas M, Thoennissen NH, Müller-Tidow C.

Clin Cancer Res. 2014 Feb 15;20(4):814-26. doi: 10.1158/1078-0432.CCR-13-1483. Epub 2013 Dec 13.

2.

Targeted inhibition of genome-wide DNA methylation analysis in epigenetically modulated phenotypes in lung cancer.

Dai SP, Xie C, Ding N, Zhang YJ, Han L, Han YW.

Med Oncol. 2015 Jun;32(6):615. doi: 10.1007/s12032-015-0615-x. Epub 2015 Apr 30.

PMID:
25926333
3.

5-azacytidine enhances efficacy of multiple chemotherapy drugs in AML and lung cancer with modulation of CpG methylation.

Füller M, Klein M, Schmidt E, Rohde C, Göllner S, Schulze I, Qianli J, Berdel WE, Edemir B, Müller-Tidow C, Tschanter P.

Int J Oncol. 2015 Mar;46(3):1192-204. doi: 10.3892/ijo.2014.2792. Epub 2014 Dec 10.

PMID:
25501798
4.

Frequent inactivation of RAMP2, EFEMP1 and Dutt1 in lung cancer by promoter hypermethylation.

Yue W, Dacic S, Sun Q, Landreneau R, Guo M, Zhou W, Siegfried JM, Yu J, Zhang L.

Clin Cancer Res. 2007 Aug 1;13(15 Pt 1):4336-44.

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Genome-wide methylation and expression profiling identifies promoter characteristics affecting demethylation-induced gene up-regulation in melanoma.

Rubinstein JC, Tran N, Ma S, Halaban R, Krauthammer M.

BMC Med Genomics. 2010 Feb 9;3:4. doi: 10.1186/1755-8794-3-4.

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Expression and methylation pattern of TSLC1 cascade genes in lung carcinomas.

Heller G, Fong KM, Girard L, Seidl S, End-Pfützenreuter A, Lang G, Gazdar AF, Minna JD, Zielinski CC, Zöchbauer-Müller S.

Oncogene. 2006 Feb 9;25(6):959-68.

PMID:
16205641
10.

[Effects of 5-Aza-2-deoxycytidine on DNA methylation of anti-oncogenes in non-small cell lung cancer cells].

Fang HL, Yu ZC, Zhu HB, Jin YT.

Zhonghua Zhong Liu Za Zhi. 2012 Sep;34(9):658-63. doi: 10.3760/cma.j.issn.0253-3766.2012.09.004. Chinese.

PMID:
23159077
11.

Epigenetic inactivation of laminin-5-encoding genes in lung cancers.

Sathyanarayana UG, Toyooka S, Padar A, Takahashi T, Brambilla E, Minna JD, Gazdar AF.

Clin Cancer Res. 2003 Jul;9(7):2665-72.

12.

Epigenetic DNA-(cytosine-5-carbon) modifications: 5-aza-2'-deoxycytidine and DNA-demethylation.

Patra SK, Bettuzzi S.

Biochemistry (Mosc). 2009 Jun;74(6):613-9. Review.

PMID:
19645665
13.

A genome-wide screen for promoter methylation in lung cancer identifies novel methylation markers for multiple malignancies.

Shames DS, Girard L, Gao B, Sato M, Lewis CM, Shivapurkar N, Jiang A, Perou CM, Kim YH, Pollack JR, Fong KM, Lam CL, Wong M, Shyr Y, Nanda R, Olopade OI, Gerald W, Euhus DM, Shay JW, Gazdar AF, Minna JD.

PLoS Med. 2006 Dec;3(12):e486.

14.

Genome-wide CpG island methylation analyses in non-small cell lung cancer patients.

Heller G, Babinsky VN, Ziegler B, Weinzierl M, Noll C, Altenberger C, Müllauer L, Dekan G, Grin Y, Lang G, End-Pfützenreuter A, Steiner I, Zehetmayer S, Döme B, Arns BM, Fong KM, Wright CM, Yang IA, Klepetko W, Posch M, Zielinski CC, Zöchbauer-Müller S.

Carcinogenesis. 2013 Mar;34(3):513-21. doi: 10.1093/carcin/bgs363. Epub 2012 Nov 19.

PMID:
23172663
15.

Epigenetic screen identifies genotype-specific promoter DNA methylation and oncogenic potential of CHRNB4.

Scherf DB, Sarkisyan N, Jacobsson H, Claus R, Bermejo JL, Peil B, Gu L, Muley T, Meister M, Dienemann H, Plass C, Risch A.

Oncogene. 2013 Jul 11;32(28):3329-38. doi: 10.1038/onc.2012.344. Epub 2012 Sep 3.

16.

Genome-wide unmasking of epigenetically silenced genes in lung adenocarcinoma from smokers and never smokers.

Tessema M, Yingling CM, Liu Y, Tellez CS, Van Neste L, Baylin SS, Belinsky SA.

Carcinogenesis. 2014 Jun;35(6):1248-57. doi: 10.1093/carcin/bgt494. Epub 2014 Jan 7.

17.

Epigenetic modulation of tumor suppressor CCAAT/enhancer binding protein alpha activity in lung cancer.

Tada Y, Brena RM, Hackanson B, Morrison C, Otterson GA, Plass C.

J Natl Cancer Inst. 2006 Mar 15;98(6):396-406.

PMID:
16537832
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Epigenetic mapping and functional analysis in a breast cancer metastasis model using whole-genome promoter tiling microarrays.

Rodenhiser DI, Andrews J, Kennette W, Sadikovic B, Mendlowitz A, Tuck AB, Chambers AF.

Breast Cancer Res. 2008;10(4):R62. doi: 10.1186/bcr2121. Epub 2008 Jul 18.

20.

5' CpG island methylation of the FHIT gene is correlated with loss of gene expression in lung and breast cancer.

Zöchbauer-Müller S, Fong KM, Maitra A, Lam S, Geradts J, Ashfaq R, Virmani AK, Milchgrub S, Gazdar AF, Minna JD.

Cancer Res. 2001 May 1;61(9):3581-5.

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