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Items: 1 to 20 of 171

1.

Identification of a selective agonist for liver X receptor α (LXRα) via screening of a synthetic compound library.

Li N, Xu Y, Feng T, Liu C, Li Y, Wang X, Si S.

J Biomol Screen. 2014 Apr;19(4):566-74. doi: 10.1177/1087057113516004.

PMID:
24334278
2.

Identification of a novel partial agonist of liver X receptor α (LXRα) via screening.

Li N, Wang X, Zhang J, Liu C, Li Y, Feng T, Xu Y, Si S.

Biochem Pharmacol. 2014 Dec 1;92(3):438-47. doi: 10.1016/j.bcp.2014.09.017.

PMID:
25450668
3.

Liver X receptor (LXR)-beta regulation in LXRalpha-deficient mice: implications for therapeutic targeting.

Quinet EM, Savio DA, Halpern AR, Chen L, Schuster GU, Gustafsson JA, Basso MD, Nambi P.

Mol Pharmacol. 2006 Oct;70(4):1340-9.

4.

Panax notoginseng saponins attenuate atherosclerosis via reciprocal regulation of lipid metabolism and inflammation by inducing liver X receptor alpha expression.

Fan JS, Liu DN, Huang G, Xu ZZ, Jia Y, Zhang HG, Li XH, He FT.

J Ethnopharmacol. 2012 Aug 1;142(3):732-8. doi: 10.1016/j.jep.2012.05.053.

PMID:
22683903
6.

α-Lipoic acid ameliorates foam cell formation via liver X receptor α-dependent upregulation of ATP-binding cassette transporters A1 and G1.

Cheng LC, Su KH, Kou YR, Shyue SK, Ching LC, Yu YB, Wu YL, Pan CC, Lee TS.

Free Radic Biol Med. 2011 Jan 1;50(1):47-54. doi: 10.1016/j.freeradbiomed.2010.10.706.

PMID:
21034810
7.

Activation of soluble guanylyl cyclase prevents foam cell formation and atherosclerosis.

Tsou CY, Chen CY, Zhao JF, Su KH, Lee HT, Lin SJ, Shyue SK, Hsiao SH, Lee TS.

Acta Physiol (Oxf). 2014 Apr;210(4):799-810. doi: 10.1111/apha.12210.

PMID:
24299003
8.

Novel effect of paeonol on the formation of foam cells: promotion of LXRα-ABCA1-dependent cholesterol efflux in macrophages.

Zhao JF, Jim Leu SJ, Shyue SK, Su KH, Wei J, Lee TS.

Am J Chin Med. 2013;41(5):1079-96. doi: 10.1142/S0192415X13500730.

PMID:
24117070
9.

Activation of liver X receptor decreases atherosclerosis in Ldlr⁻/⁻ mice in the absence of ATP-binding cassette transporters A1 and G1 in myeloid cells.

Kappus MS, Murphy AJ, Abramowicz S, Ntonga V, Welch CL, Tall AR, Westerterp M.

Arterioscler Thromb Vasc Biol. 2014 Feb;34(2):279-84. doi: 10.1161/ATVBAHA.113.302781.

10.

Different roles of liver X receptor alpha and beta in lipid metabolism: effects of an alpha-selective and a dual agonist in mice deficient in each subtype.

Lund EG, Peterson LB, Adams AD, Lam MH, Burton CA, Chin J, Guo Q, Huang S, Latham M, Lopez JC, Menke JG, Milot DP, Mitnaul LJ, Rex-Rabe SE, Rosa RL, Tian JY, Wright SD, Sparrow CP.

Biochem Pharmacol. 2006 Feb 14;71(4):453-63.

PMID:
16325781
11.
12.

Adiponectin upregulates ABCA1 expression through liver X receptor alpha signaling pathway in RAW 264.7 macrophages.

Liang B, Wang X, Guo X, Yang Z, Bai R, Liu M, Xiao C, Bian Y.

Int J Clin Exp Pathol. 2015 Jan 1;8(1):450-7.

13.

Differential regulation of gene expression by LXRs in response to macrophage cholesterol loading.

Ignatova ID, Angdisen J, Moran E, Schulman IG.

Mol Endocrinol. 2013 Jul;27(7):1036-47. doi: 10.1210/me.2013-1051.

14.

Unsaturated fatty acids repress expression of ATP binding cassette transporter A1 and G1 in RAW 264.7 macrophages.

Ku CS, Park Y, Coleman SL, Lee J.

J Nutr Biochem. 2012 Oct;23(10):1271-6. doi: 10.1016/j.jnutbio.2011.07.007.

PMID:
22209005
15.

PAPP-A negatively regulates ABCA1, ABCG1 and SR-B1 expression by inhibiting LXRα through the IGF-I-mediated signaling pathway.

Tang SL, Chen WJ, Yin K, Zhao GJ, Mo ZC, Lv YC, Ouyang XP, Yu XH, Kuang HJ, Jiang ZS, Fu YC, Tang CK.

Atherosclerosis. 2012 Jun;222(2):344-54. doi: 10.1016/j.atherosclerosis.2012.03.005.

PMID:
22503545
16.

Poly(ADP-ribose) Polymerase 1 Represses Liver X Receptor-mediated ABCA1 Expression and Cholesterol Efflux in Macrophages.

Shrestha E, Hussein MA, Savas JN, Ouimet M, Barrett TJ, Leone S, Yates JR 3rd, Moore KJ, Fisher EA, Garabedian MJ.

J Biol Chem. 2016 May 20;291(21):11172-84. doi: 10.1074/jbc.M116.726729.

PMID:
27026705
17.
18.

Nifedipine enhances cholesterol efflux in RAW264.7 macrophages.

Zhang Q, Ma AZ, Song ZY, Wang C, Fu XD.

Cardiovasc Drugs Ther. 2013 Oct;27(5):425-31. doi: 10.1007/s10557-013-6472-y.

PMID:
23812592
19.

Anti-atherosclerotic potential of baicalin mediated by promoting cholesterol efflux from macrophages via the PPARγ-LXRα-ABCA1/ABCG1 pathway.

He XW, Yu D, Li WL, Zheng Z, Lv CL, Li C, Liu P, Xu CQ, Hu XF, Jin XP.

Biomed Pharmacother. 2016 Oct;83:257-264. doi: 10.1016/j.biopha.2016.06.046.

PMID:
27389392
20.

Group X secretory phospholipase A2 negatively regulates ABCA1 and ABCG1 expression and cholesterol efflux in macrophages.

Shridas P, Bailey WM, Gizard F, Oslund RC, Gelb MH, Bruemmer D, Webb NR.

Arterioscler Thromb Vasc Biol. 2010 Oct;30(10):2014-21. doi: 10.1161/ATVBAHA.110.210237.

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