Format
Sort by
Items per page

Send to

Choose Destination

Links from PubMed

Items: 1 to 20 of 386

1.

Blockade of peripheral P2Y1 receptors prevents the induction of thermal hyperalgesia via modulation of TRPV1 expression in carrageenan-induced inflammatory pain rats: involvement of p38 MAPK phosphorylation in DRGs.

Kwon SG, Roh DH, Yoon SY, Moon JY, Choi SR, Choi HS, Kang SY, Han HJ, Beitz AJ, Lee JH.

Neuropharmacology. 2014 Apr;79:368-79. doi: 10.1016/j.neuropharm.2013.12.005. Epub 2013 Dec 12.

PMID:
24333674
2.

Acid evoked thermal hyperalgesia involves peripheral P2Y1 receptor mediated TRPV1 phosphorylation in a rodent model of thrombus induced ischemic pain.

Kwon SG, Roh DH, Yoon SY, Moon JY, Choi SR, Choi HS, Kang SY, Han HJ, Beitz AJ, Oh SB, Lee JH.

Mol Pain. 2014 Jan 9;10:2. doi: 10.1186/1744-8069-10-2.

3.
4.

P2Y1 purinoceptor inhibition reduces extracellular signal-regulated protein kinase 1/2 phosphorylation in spinal cord and dorsal root ganglia: implications for cancer-induced bone pain.

Chen J, Wang L, Zhang Y, Yang J.

Acta Biochim Biophys Sin (Shanghai). 2012 Apr;44(4):367-72. doi: 10.1093/abbs/gms007. Epub 2012 Feb 19.

PMID:
22349022
5.

Role of mitogen-activated protein kinase activation in injured and intact primary afferent neurons for mechanical and heat hypersensitivity after spinal nerve ligation.

Obata K, Yamanaka H, Kobayashi K, Dai Y, Mizushima T, Katsura H, Fukuoka T, Tokunaga A, Noguchi K.

J Neurosci. 2004 Nov 10;24(45):10211-22.

6.

Sigma-1 receptor-mediated increase in spinal p38 MAPK phosphorylation leads to the induction of mechanical allodynia in mice and neuropathic rats.

Moon JY, Roh DH, Yoon SY, Kang SY, Choi SR, Kwon SG, Choi HS, Han HJ, Beitz AJ, Lee JH.

Exp Neurol. 2013 Sep;247:383-91. doi: 10.1016/j.expneurol.2013.01.004. Epub 2013 Jan 15.

PMID:
23333567
7.

Involvement of peripheral P2Y1 receptors and potential interaction with IL-1 receptors in IL-1β-induced thermal hypersensitivity in rats.

Kwon SG, Roh DH, Yoon SY, Choi SR, Choi HS, Moon JY, Kang SY, Beitz AJ, Lee JH.

Brain Res Bull. 2017 Apr;130:165-172. doi: 10.1016/j.brainresbull.2017.01.019. Epub 2017 Jan 30.

PMID:
28153540
8.

p38 MAPK Mediates Glial P2X7R-Neuronal P2Y1R Inhibitory Control of P2X3R Expression in Dorsal Root Ganglion Neurons.

Chen Y, Li G, Huang LY.

Mol Pain. 2016 Sep 21;11. pii: s12990-015-0073-7. doi: 10.1186/s12990-015-0073-7. Print 2015 Jan.

PMID:
27655923
9.

LASSBio-1135: a dual TRPV1 antagonist and anti-TNF-alpha compound orally effective in models of inflammatory and neuropathic pain.

Lima CK, Silva RM, Lacerda RB, Santos BL, Silva RV, Amaral LS, Quintas LE, Fraga CA, Barreiro EJ, Guimaraes MZ, Miranda AL.

PLoS One. 2014 Jun 18;9(6):e99510. doi: 10.1371/journal.pone.0099510. eCollection 2014.

10.

RhoA/ROCK pathway mediates p38 MAPK activation and morphological changes downstream of P2Y12/13 receptors in spinal microglia in neuropathic pain.

Tatsumi E, Yamanaka H, Kobayashi K, Yagi H, Sakagami M, Noguchi K.

Glia. 2015 Feb;63(2):216-28. doi: 10.1002/glia.22745. Epub 2014 Aug 14.

PMID:
25130721
11.

Analgesic Effect of Electroacupuncture in a Mouse Fibromyalgia Model: Roles of TRPV1, TRPV4, and pERK.

Lin JG, Hsieh CL, Lin YW.

PLoS One. 2015 Jun 4;10(6):e0128037. doi: 10.1371/journal.pone.0128037. eCollection 2015.

12.

Activation of p38 MAPK in primary afferent neurons by noxious stimulation and its involvement in the development of thermal hyperalgesia.

Mizushima T, Obata K, Yamanaka H, Dai Y, Fukuoka T, Tokunaga A, Mashimo T, Noguchi K.

Pain. 2005 Jan;113(1-2):51-60.

PMID:
15621364
13.

Activation of TRPV1 contributes to morphine tolerance: involvement of the mitogen-activated protein kinase signaling pathway.

Chen Y, Geis C, Sommer C.

J Neurosci. 2008 May 28;28(22):5836-45. doi: 10.1523/JNEUROSCI.4170-07.2008.

14.

Melanocortin 4 receptor induces hyperalgesia and allodynia after chronic constriction injury by activation of p38 MAPK in DRG.

Chu H, Xia J, Yang Z, Gao J.

Int J Neurosci. 2012 Feb;122(2):74-81. doi: 10.3109/00207454.2011.630542. Epub 2011 Nov 24.

PMID:
21985621
17.

Clonidine, an alpha-2 adrenoceptor agonist relieves mechanical allodynia in oxaliplatin-induced neuropathic mice; potentiation by spinal p38 MAPK inhibition without motor dysfunction and hypotension.

Yeo JH, Yoon SY, Kim SJ, Oh SB, Lee JH, Beitz AJ, Roh DH.

Int J Cancer. 2016 May 15;138(10):2466-76. doi: 10.1002/ijc.29980. Epub 2016 Jan 11.

18.

NF-κB, ERK, p38 MAPK and JNK contribute to the initiation and/or maintenance of mechanical allodynia induced by tumor necrosis factor-alpha in the red nucleus.

Zhang Q, Wang J, Duan MT, Han SP, Zeng XY, Wang JY.

Brain Res Bull. 2013 Oct;99:132-9. doi: 10.1016/j.brainresbull.2013.10.008. Epub 2013 Oct 23.

PMID:
24161765
19.

TRESK contributes to pain threshold changes by mediating apoptosis via MAPK pathway in the spinal cord.

Zhou J, Lin W, Chen H, Fan Y, Yang C.

Neuroscience. 2016 Dec 17;339:622-633. doi: 10.1016/j.neuroscience.2016.10.039. Epub 2016 Oct 24.

PMID:
27789381
20.

Shp-1 dephosphorylates TRPV1 in dorsal root ganglion neurons and alleviates CFA-induced inflammatory pain in rats.

Xiao X, Zhao XT, Xu LC, Yue LP, Liu FY, Cai J, Liao FF, Kong JG, Xing GG, Yi M, Wan Y.

Pain. 2015 Apr;156(4):597-608. doi: 10.1097/01.j.pain.0000460351.30707.c4.

PMID:
25790452

Supplemental Content

Support Center