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Items: 1 to 20 of 161

1.

Caffeine induces tumor cytotoxicity via the regulation of alternative splicing in subsets of cancer-associated genes.

Lu GY, Huang SM, Liu ST, Liu PY, Chou WY, Lin WS.

Int J Biochem Cell Biol. 2014 Feb;47:83-92. doi: 10.1016/j.biocel.2013.12.004. Epub 2013 Dec 12.

PMID:
24333670
2.

Multiple effects of digoxin on subsets of cancer-associated genes through the alternative splicing pathway.

Lu GY, Liu ST, Huang SM, Chang YL, Lin WS.

Biochimie. 2014 Nov;106:131-9. doi: 10.1016/j.biochi.2014.08.013. Epub 2014 Sep 3.

PMID:
25193633
3.

Downregulation of splicing factor SRSF3 induces p53β, an alternatively spliced isoform of p53 that promotes cellular senescence.

Tang Y, Horikawa I, Ajiro M, Robles AI, Fujita K, Mondal AM, Stauffer JK, Zheng ZM, Harris CC.

Oncogene. 2013 May 30;32(22):2792-8. doi: 10.1038/onc.2012.288. Epub 2012 Jul 9.

PMID:
22777358
4.

Caffeine regulates alternative splicing in a subset of cancer-associated genes: a role for SC35.

Shi J, Hu Z, Pabon K, Scotto KW.

Mol Cell Biol. 2008 Jan;28(2):883-95. Epub 2007 Nov 19.

5.

Downregulation of serine/arginine-rich splicing factor 3 induces G1 cell cycle arrest and apoptosis in colon cancer cells.

Kurokawa K, Akaike Y, Masuda K, Kuwano Y, Nishida K, Yamagishi N, Kajita K, Tanahashi T, Rokutan K.

Oncogene. 2014 Mar 13;33(11):1407-17. doi: 10.1038/onc.2013.86. Epub 2013 Mar 18.

PMID:
23503458
6.

Hepatocyte growth factor enhances alternative splicing of the Kruppel-like factor 6 (KLF6) tumor suppressor to promote growth through SRSF1.

Muñoz Ú, Puche JE, Hannivoort R, Lang UE, Cohen-Naftaly M, Friedman SL.

Mol Cancer Res. 2012 Sep;10(9):1216-27. Epub 2012 Aug 2.

7.
8.

Oxidative stress-inducible truncated serine/arginine-rich splicing factor 3 regulates interleukin-8 production in human colon cancer cells.

Kano S, Nishida K, Kurebe H, Nishiyama C, Kita K, Akaike Y, Kajita K, Kurokawa K, Masuda K, Kuwano Y, Tanahashi T, Rokutan K.

Am J Physiol Cell Physiol. 2014 Feb 1;306(3):C250-62. doi: 10.1152/ajpcell.00091.2013. Epub 2013 Nov 27.

PMID:
24284797
9.

Human Papillomavirus 16 Oncoprotein Expression Is Controlled by the Cellular Splicing Factor SRSF2 (SC35).

McFarlane M, MacDonald AI, Stevenson A, Graham SV.

J Virol. 2015 May;89(10):5276-87. doi: 10.1128/JVI.03434-14. Epub 2015 Feb 25.

10.

SRSF3 represses the expression of PDCD4 protein by coordinated regulation of alternative splicing, export and translation.

Park SK, Jeong S.

Biochem Biophys Res Commun. 2016 Feb 5;470(2):431-438. doi: 10.1016/j.bbrc.2016.01.019. Epub 2016 Jan 8.

PMID:
26773498
11.

Splicing factor SRSF3 represses the translation of programmed cell death 4 mRNA by associating with the 5'-UTR region.

Kim J, Park RY, Chen JK, Kim J, Jeong S, Ohn T.

Cell Death Differ. 2014 Mar;21(3):481-90. doi: 10.1038/cdd.2013.171. Epub 2013 Nov 29.

12.

Modulation of p53β and p53γ expression by regulating the alternative splicing of TP53 gene modifies cellular response.

Marcel V, Fernandes K, Terrier O, Lane DP, Bourdon JC.

Cell Death Differ. 2014 Sep;21(9):1377-87. doi: 10.1038/cdd.2014.73. Epub 2014 Jun 13.

13.

A germline DNA polymorphism enhances alternative splicing of the KLF6 tumor suppressor gene and is associated with increased prostate cancer risk.

Narla G, Difeo A, Reeves HL, Schaid DJ, Hirshfeld J, Hod E, Katz A, Isaacs WB, Hebbring S, Komiya A, McDonnell SK, Wiley KE, Jacobsen SJ, Isaacs SD, Walsh PC, Zheng SL, Chang BL, Friedrichsen DM, Stanford JL, Ostrander EA, Chinnaiyan AM, Rubin MA, Xu J, Thibodeau SN, Friedman SL, Martignetti JA.

Cancer Res. 2005 Feb 15;65(4):1213-22.

14.

Genotoxic stress induces coordinately regulated alternative splicing of the p53 modulators MDM2 and MDM4.

Chandler DS, Singh RK, Caldwell LC, Bitler JL, Lozano G.

Cancer Res. 2006 Oct 1;66(19):9502-8.

15.

Akt2 regulation of Cdc2-like kinases (Clk/Sty), serine/arginine-rich (SR) protein phosphorylation, and insulin-induced alternative splicing of PKCbetaII messenger ribonucleic acid.

Jiang K, Patel NA, Watson JE, Apostolatos H, Kleiman E, Hanson O, Hagiwara M, Cooper DR.

Endocrinology. 2009 May;150(5):2087-97. doi: 10.1210/en.2008-0818. Epub 2008 Dec 30.

16.

Loss of Pnn expression attenuates expression levels of SR family splicing factors and modulates alternative pre-mRNA splicing in vivo.

Chiu Y, Ouyang P.

Biochem Biophys Res Commun. 2006 Mar 10;341(2):663-71. Epub 2006 Jan 17.

PMID:
16430868
17.

Deletion of serine/arginine-rich splicing factor 3 in hepatocytes predisposes to hepatocellular carcinoma in mice.

Sen S, Langiewicz M, Jumaa H, Webster NJ.

Hepatology. 2015 Jan;61(1):171-83. doi: 10.1002/hep.27380. Epub 2014 Nov 25.

18.

Serine/arginine-rich splicing factor 3 (SRSF3) regulates homologous recombination-mediated DNA repair.

He X, Zhang P.

Mol Cancer. 2015 Aug 19;14:158. doi: 10.1186/s12943-015-0422-1.

19.

Osteopontin-c isoform levels are associated with SR and hnRNP differential expression in ovarian cancer cell lines.

Marques DS, Grativol J, Alves da Silva Peres R, da Rocha Matos A, Gimba ERP.

Tumour Biol. 2017 Sep;39(9):1010428317725442. doi: 10.1177/1010428317725442.

PMID:
28936921
20.

Splicing factor Tra2-beta1 is specifically induced in breast cancer and regulates alternative splicing of the CD44 gene.

Watermann DO, Tang Y, Zur Hausen A, Jäger M, Stamm S, Stickeler E.

Cancer Res. 2006 May 1;66(9):4774-80.

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