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Type I interferons up-regulate the expression and signalling of p75 NTR/TrkA receptor complex in differentiated human SH-SY5Y neuroblastoma cells.

Dedoni S, Olianas MC, Ingianni A, Onali P. Dedoni S, et al. Neuropharmacology. 2014 Apr;79:321-34. doi: 10.1016/j.neuropharm.2013.12.002. Epub 2013 Dec 11. Neuropharmacology. 2014. PMID: 24333329

NGF and ProNGF: Regulation of neuronal and neoplastic responses through receptor signaling.

Bradshaw RA, Pundavela J, Biarc J, Chalkley RJ, Burlingame AL, Hondermarck H. Bradshaw RA, et al. Adv Biol Regul. 2015 May;58:16-27. doi: 10.1016/j.jbior.2014.11.003. Epub 2014 Nov 20. Adv Biol Regul. 2015. PMID: 25491371 Free PMC article. Review.

Nerve growth factor survival signaling in cultured hippocampal neurons is mediated through TrkA and requires the common neurotrophin receptor P75.

Culmsee C, Gerling N, Lehmann M, Nikolova-Karakashian M, Prehn JH, Mattson MP, Krieglstein J. Culmsee C, et al. Neuroscience. 2002;115(4):1089-108. doi: 10.1016/s0306-4522(02)00539-0. Neuroscience. 2002. PMID: 12453482

Sortilin is essential for proNGF-induced neuronal cell death.

Nykjaer A, Lee R, Teng KK, Jansen P, Madsen P, Nielsen MS, Jacobsen C, Kliemannel M, Schwarz E, Willnow TE, Hempstead BL, Petersen CM. Nykjaer A, et al. Nature. 2004 Feb 26;427(6977):843-8. doi: 10.1038/nature02319. Nature. 2004. PMID: 14985763

ProNGF, but Not NGF, Switches from Neurotrophic to Apoptotic Activity in Response to Reductions in TrkA Receptor Levels.

Ioannou MS, Fahnestock M. Ioannou MS, et al. Int J Mol Sci. 2017 Mar 9;18(3):599. doi: 10.3390/ijms18030599. Int J Mol Sci. 2017. PMID: 28282920 Free PMC article.

Human ProNGF: biological effects and binding profiles at TrkA, P75NTR and sortilin.

Clewes O, Fahey MS, Tyler SJ, Watson JJ, Seok H, Catania C, Cho K, Dawbarn D, Allen SJ. Clewes O, et al. J Neurochem. 2008 Nov;107(4):1124-35. doi: 10.1111/j.1471-4159.2008.05698.x. Epub 2008 Sep 21. J Neurochem. 2008. PMID: 18808449 Free article.

Functional interaction between p75NTR and TrkA: the endocytic trafficking of p75NTR is driven by TrkA and regulates TrkA-mediated signalling.

Perrone L, Paladino S, Mazzone M, Nitsch L, Gulisano M, Zurzolo C. Perrone L, et al. Biochem J. 2005 Jan 1;385(Pt 1):233-41. doi: 10.1042/BJ20041155. Biochem J. 2005. PMID: 15330756 Free PMC article.

The p75 neurotrophin receptor enhances TrkA signalling by binding to Shc and augmenting its phosphorylation.

Epa WR, Markovska K, Barrett GL. Epa WR, et al. J Neurochem. 2004 Apr;89(2):344-53. doi: 10.1111/j.1471-4159.2004.02344.x. J Neurochem. 2004. PMID: 15056278 Free article.

Nerve growth factor-induced protein kinase C stimulation contributes to TrkA-dependent inhibition of p75 neurotrophin receptor sphingolipid signaling.

Plo I, Bono F, Bezombes C, Alam A, Bruno A, Laurent G. Plo I, et al. J Neurosci Res. 2004 Aug 15;77(4):465-74. doi: 10.1002/jnr.20189. J Neurosci Res. 2004. PMID: 15264216

Expression of NGF/proNGF and Their Receptors TrkA, p75^NTR and Sortilin in Melanoma.

Marsland M, Dowdell A, Jiang CC, Wilmott JS, Scolyer RA, Zhang XD, Hondermarck H, Faulkner S. Marsland M, et al. Int J Mol Sci. 2022 Apr 12;23(8):4260. doi: 10.3390/ijms23084260. Int J Mol Sci. 2022. PMID: 35457078 Free PMC article.

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