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Items: 1 to 20 of 155


New players in high fat diet-induced obesity: LETM1 and CTMP.

Park J, Li Y, Kim SH, Yang KJ, Kong G, Shrestha R, Tran Q, Park KA, Jeon J, Hur GM, Lee CH, Kim DH, Park J.

Metabolism. 2014 Mar;63(3):318-27. doi: 10.1016/j.metabol.2013.10.012. Epub 2013 Oct 31.


Co-delivery of LETM1 and CTMP synergistically inhibits tumor growth in H-ras12V liver cancer model mice.

Shin JY, Chung YS, Kang B, Jiang HL, Yu DY, Han K, Chae C, Moon JH, Jang G, Cho MH.

Cancer Gene Ther. 2013 Mar;20(3):186-94. doi: 10.1038/cgt.2013.6. Epub 2013 Feb 8.


Carboxyl-terminal modulator protein (CTMP), a negative regulator of PKB/Akt and v-Akt at the plasma membrane.

Maira SM, Galetic I, Brazil DP, Kaech S, Ingley E, Thelen M, Hemmings BA.

Science. 2001 Oct 12;294(5541):374-80.


Regulation of OPA1-mediated mitochondrial fusion by leucine zipper/EF-hand-containing transmembrane protein-1 plays a role in apoptosis.

Piao L, Li Y, Kim SJ, Sohn KC, Yang KJ, Park KA, Byun HS, Won M, Hong J, Hur GM, Seok JH, Shong M, Sack R, Brazil DP, Hemmings BA, Park J.

Cell Signal. 2009 May;21(5):767-77. doi: 10.1016/j.cellsig.2009.01.020. Epub 2009 Jan 9.


Carboxy-terminal modulator protein induces Akt phosphorylation and activation, thereby enhancing antiapoptotic, glycogen synthetic, and glucose uptake pathways.

Ono H, Sakoda H, Fujishiro M, Anai M, Kushiyama A, Fukushima Y, Katagiri H, Ogihara T, Oka Y, Kamata H, Horike N, Uchijima Y, Kurihara H, Asano T.

Am J Physiol Cell Physiol. 2007 Nov;293(5):C1576-85. Epub 2007 Jul 5.


Carboxyl-terminal modulator protein positively regulates Akt phosphorylation and acts as an oncogenic driver in breast cancer.

Liu YP, Liao WC, Ger LP, Chen JC, Hsu TI, Lee YC, Chang HT, Chen YC, Jan YH, Lee KH, Zeng YH, Hsiao M, Lu PJ.

Cancer Res. 2013 Oct 15;73(20):6194-205. doi: 10.1158/0008-5472.CAN-13-0518. Epub 2013 Aug 13.


High-fat diet alters PP2A, TC10, and CIP4 expression in visceral adipose tissue of rats.

Jun HS, Hwang K, Kim Y, Park T.

Obesity (Silver Spring). 2008 Jun;16(6):1226-31. doi: 10.1038/oby.2008.220. Epub 2008 Apr 3.


Heat shock protein 70-mediated sensitization of cells to apoptosis by Carboxyl-Terminal Modulator Protein.

Piao L, Li Y, Yang KJ, Park KA, Byun HS, Won M, Hong J, Kim JL, Kweon GR, Hur GM, Seok JH, Cho JY, Chun T, Hess D, Sack R, Maira SM, Brazil DP, Hemmings BA, Park J.

BMC Cell Biol. 2009 Jul 15;10:53. doi: 10.1186/1471-2121-10-53.


Activation of Akt independent of PTEN and CTMP tumor-suppressor gene mutations in epilepsy-associated Taylor-type focal cortical dysplasias.

Schick V, Majores M, Engels G, Spitoni S, Koch A, Elger CE, Simon M, Knobbe C, Blümcke I, Becker AJ.

Acta Neuropathol. 2006 Dec;112(6):715-25. Epub 2006 Sep 30.


C1q/TNF-related protein-12 (CTRP12), a novel adipokine that improves insulin sensitivity and glycemic control in mouse models of obesity and diabetes.

Wei Z, Peterson JM, Lei X, Cebotaru L, Wolfgang MJ, Baldeviano GC, Wong GW.

J Biol Chem. 2012 Mar 23;287(13):10301-15. doi: 10.1074/jbc.M111.303651. Epub 2012 Jan 24.


Hypermethylation and transcriptional downregulation of the carboxyl-terminal modulator protein gene in glioblastomas.

Knobbe CB, Reifenberger J, Blaschke B, Reifenberger G.

J Natl Cancer Inst. 2004 Mar 17;96(6):483-6.


Subcellular localization of glucose transporter 4 in the hypothalamic arcuate nucleus of ob/ob mice under basal conditions.

Komori T, Morikawa Y, Tamura S, Doi A, Nanjo K, Senba E.

Brain Res. 2005 Jul 5;1049(1):34-42.


Disruption of the SH2-B gene causes age-dependent insulin resistance and glucose intolerance.

Duan C, Yang H, White MF, Rui L.

Mol Cell Biol. 2004 Sep;24(17):7435-43.


Obesity-induced increase in tumor necrosis factor-α leads to development of colon cancer in mice.

Flores MB, Rocha GZ, Damas-Souza DM, Osório-Costa F, Dias MM, Ropelle ER, Camargo JA, de Carvalho RB, Carvalho HF, Saad MJ, Carvalheira JB.

Gastroenterology. 2012 Sep;143(3):741-53.e1-4. doi: 10.1053/j.gastro.2012.05.045. Epub 2012 Jun 4.


Fucosylated chondroitin sulfate from sea cucumber improves insulin sensitivity via activation of PI3K/PKB pathway.

Hu S, Chang Y, He M, Wang J, Wang Y, Xue C.

J Food Sci. 2014 Jul;79(7):H1424-9. doi: 10.1111/1750-3841.12465.


Chlorella modulates insulin signaling pathway and prevents high-fat diet-induced insulin resistance in mice.

Vecina JF, Oliveira AG, Araujo TG, Baggio SR, Torello CO, Saad MJ, Queiroz ML.

Life Sci. 2014 Jan 24;95(1):45-52. doi: 10.1016/j.lfs.2013.11.020. Epub 2013 Dec 11.


Carboxy-Terminal Modulator Protein (CTMP) is a mitochondrial protein that sensitizes cells to apoptosis.

Parcellier A, Tintignac LA, Zhuravleva E, Cron P, Schenk S, Bozulic L, Hemmings BA.

Cell Signal. 2009 Apr;21(4):639-50. doi: 10.1016/j.cellsig.2009.01.016. Epub 2009 Jan 8.


High-fat diet obesity associated with insulin resistance increases cell proliferation, estrogen receptor, and PI3K proteins in rat ventral prostate.

Ribeiro DL, Pinto ME, Rafacho A, Bosqueiro JR, Maeda SY, Anselmo-Franci JA, Taboga SR, Góes RM.

J Androl. 2012 Sep-Oct;33(5):854-65. Epub 2012 Mar 22.


Signaling mechanisms involved in altered function of macrophages from diet-induced obese mice affect immune responses.

Zhou Q, Leeman SE, Amar S.

Proc Natl Acad Sci U S A. 2009 Jun 30;106(26):10740-5. doi: 10.1073/pnas.0904412106. Epub 2009 Jun 17.


The skeletal muscle Wnt pathway may modulate insulin resistance and muscle development in a diet-induced obese rat model.

Zhou D, Strakovsky RS, Zhang X, Pan YX.

Obesity (Silver Spring). 2012 Aug;20(8):1577-84. doi: 10.1038/oby.2012.42. Epub 2012 Feb 21.

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