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Items: 1 to 20 of 51

1.

An optimized microRNA backbone for effective single-copy RNAi.

Fellmann C, Hoffmann T, Sridhar V, Hopfgartner B, Muhar M, Roth M, Lai DY, Barbosa IA, Kwon JS, Guan Y, Sinha N, Zuber J.

Cell Rep. 2013 Dec 26;5(6):1704-13. doi: 10.1016/j.celrep.2013.11.020. Epub 2013 Dec 12.

2.

An optimized lentiviral vector system for conditional RNAi and efficient cloning of microRNA embedded short hairpin RNA libraries.

Adams FF, Heckl D, Hoffmann T, Talbot SR, Kloos A, Thol F, Heuser M, Zuber J, Schambach A, Schwarzer A.

Biomaterials. 2017 Sep;139:102-115. doi: 10.1016/j.biomaterials.2017.05.032. Epub 2017 May 23.

PMID:
28599149
3.

Efficient gene knockdowns in mouse embryonic stem cells using microRNA-based shRNAs.

Wang J.

Methods Mol Biol. 2010;650:241-56. doi: 10.1007/978-1-60761-769-3_18.

PMID:
20686956
4.

A miR-21 hairpin structure-based gene knockdown vector.

Yue J, Sheng Y, Ren A, Penmatsa S.

Biochem Biophys Res Commun. 2010 Apr 9;394(3):667-72. doi: 10.1016/j.bbrc.2010.03.047. Epub 2010 Mar 11.

5.

Improved knockdown from artificial microRNAs in an enhanced miR-155 backbone: a designer's guide to potent multi-target RNAi.

Fowler DK, Williams C, Gerritsen AT, Washbourne P.

Nucleic Acids Res. 2016 Mar 18;44(5):e48. doi: 10.1093/nar/gkv1246. Epub 2015 Nov 17.

6.

Generation of transgenic Drosophila expressing shRNAs in the miR-1 backbone.

Chang K, Marran K, Valentine A, Hannon GJ.

Cold Spring Harb Protoc. 2014 May 1;2014(5). pii: pdb.prot080762. doi: 10.1101/pdb.prot080762.

7.

miR-138 overexpression is more powerful than hTERT knockdown to potentiate apigenin for apoptosis in neuroblastoma in vitro and in vivo.

Chakrabarti M, Banik NL, Ray SK.

Exp Cell Res. 2013 Jun 10;319(10):1575-85. doi: 10.1016/j.yexcr.2013.02.025. Epub 2013 Apr 3.

8.

Functional identification of optimized RNAi triggers using a massively parallel sensor assay.

Fellmann C, Zuber J, McJunkin K, Chang K, Malone CD, Dickins RA, Xu Q, Hengartner MO, Elledge SJ, Hannon GJ, Lowe SW.

Mol Cell. 2011 Mar 18;41(6):733-46. doi: 10.1016/j.molcel.2011.02.008. Epub 2011 Feb 25.

9.

Polymerase II promoter strength determines efficacy of microRNA adapted shRNAs.

Lebbink RJ, Lowe M, Chan T, Khine H, Wang X, McManus MT.

PLoS One. 2011;6(10):e26213. doi: 10.1371/journal.pone.0026213. Epub 2011 Oct 21.

10.

Optimized gene silencing by co-expression of multiple shRNAs in a single vector.

Ishigaki Y, Nagao A, Matsunaga T.

Methods Mol Biol. 2010;623:109-21. doi: 10.1007/978-1-60761-588-0_7.

PMID:
20217547
11.

Efficient Gene Knockdowns in Mouse Embryonic Stem Cells Using MicroRNA-Based shRNAs.

Wang J.

Methods Mol Biol. 2017;1622:241-254. doi: 10.1007/978-1-4939-7108-4_17.

PMID:
28674813
12.

Vector-based RNAi approaches for stable, inducible and genome-wide screens.

Fewell GD, Schmitt K.

Drug Discov Today. 2006 Nov;11(21-22):975-82. Epub 2006 Sep 26. Review.

PMID:
17055406
13.

A lentiviral microRNA-based system for single-copy polymerase II-regulated RNA interference in mammalian cells.

Stegmeier F, Hu G, Rickles RJ, Hannon GJ, Elledge SJ.

Proc Natl Acad Sci U S A. 2005 Sep 13;102(37):13212-7. Epub 2005 Sep 1.

14.

Optimization of shRNA inhibitors by variation of the terminal loop sequence.

Schopman NC, Liu YP, Konstantinova P, ter Brake O, Berkhout B.

Antiviral Res. 2010 May;86(2):204-11. doi: 10.1016/j.antiviral.2010.02.320. Epub 2010 Feb 25.

PMID:
20188764
15.

Requirements for human Dicer and TRBP in microRNA-122 regulation of HCV translation and RNA abundance.

Zhang C, Huys A, Thibault PA, Wilson JA.

Virology. 2012 Nov 25;433(2):479-88. doi: 10.1016/j.virol.2012.08.039. Epub 2012 Sep 19.

16.

Enhanced gene silencing of HIV-1 specific siRNA using microRNA designed hairpins.

Boden D, Pusch O, Silbermann R, Lee F, Tucker L, Ramratnam B.

Nucleic Acids Res. 2004 Feb 13;32(3):1154-8. Print 2004.

17.

Effective knockdown of multiple target genes by expressing the single transcript harbouring multi-cistronic shRNAs.

Junn HJ, Kim JY, Seol DW.

Biochem Biophys Res Commun. 2010 Jun 11;396(4):861-5. doi: 10.1016/j.bbrc.2010.05.008. Epub 2010 May 6.

PMID:
20451494
18.

Fatality in mice due to oversaturation of cellular microRNA/short hairpin RNA pathways.

Grimm D, Streetz KL, Jopling CL, Storm TA, Pandey K, Davis CR, Marion P, Salazar F, Kay MA.

Nature. 2006 May 25;441(7092):537-41.

PMID:
16724069
19.

Short hairpin RNA-mediated gene silencing.

Lambeth LS, Smith CA.

Methods Mol Biol. 2013;942:205-32. doi: 10.1007/978-1-62703-119-6_12. Review.

PMID:
23027054
20.

Functional selection of shRNA loops from randomized retroviral libraries.

Jensen SM, Schmitz A, Pedersen FS, Kjems J, Bramsen JB.

PLoS One. 2012;7(8):e43095. doi: 10.1371/journal.pone.0043095. Epub 2012 Aug 17.

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