Sort by
Items per page

Send to

Choose Destination

Links from PubMed

Items: 1 to 20 of 93


Synthesis of 3'-O-fluorescently mono-modified reversible terminators and their uses in sequencing-by-synthesis.

Kim DR, Kim TS, Kim E, Min SJ, Shin D, Ahn DR.

Bioorg Med Chem Lett. 2014 Jan 1;24(1):209-13. doi: 10.1016/j.bmcl.2013.11.040. Epub 2013 Nov 25.


Synthesis of four colors fluorescently labelled 3'-O-blocked nucleotides with fluoride cleavable blocking group and linker for array based Sequencing-by-Synthesis applications.

Knapp DC, Keller A, D'Onofrio J, Lubys A, Serva S, Kurg A, Remm M, Kwiatkowski M, Engels JW.

Nucleic Acids Symp Ser (Oxf). 2008;(52):345-6. doi: 10.1093/nass/nrn174.


A new class of cleavable fluorescent nucleotides: synthesis and optimization as reversible terminators for DNA sequencing by synthesis.

Turcatti G, Romieu A, Fedurco M, Tairi AP.

Nucleic Acids Res. 2008 Mar;36(4):e25. doi: 10.1093/nar/gkn021. Epub 2008 Feb 7.


An integrated system for DNA sequencing by synthesis using novel nucleotide analogues.

Guo J, Yu L, Turro NJ, Ju J.

Acc Chem Res. 2010 Apr 20;43(4):551-63. doi: 10.1021/ar900255c.


Four-color DNA sequencing by synthesis using cleavable fluorescent nucleotide reversible terminators.

Ju J, Kim DH, Bi L, Meng Q, Bai X, Li Z, Li X, Marma MS, Shi S, Wu J, Edwards JR, Romu A, Turro NJ.

Proc Natl Acad Sci U S A. 2006 Dec 26;103(52):19635-40. Epub 2006 Dec 14.


Rapid incorporation kinetics and improved fidelity of a novel class of 3'-OH unblocked reversible terminators.

Gardner AF, Wang J, Wu W, Karouby J, Li H, Stupi BP, Jack WE, Hersh MN, Metzker ML.

Nucleic Acids Res. 2012 Aug;40(15):7404-15. doi: 10.1093/nar/gks330. Epub 2012 May 8.


The fluoride cleavable 2-(cyanoethoxy)methyl (CEM) group as reversible 3'-O-terminator for DNA sequencing-by-synthesis - synthesis, incorporation, and cleavage.

Földesi A, Keller A, Stura A, Zigmantas S, Kwiatkowski M, Knapp D, Engels JW.

Nucleosides Nucleotides Nucleic Acids. 2007;26(3):271-5.


Fluoride-cleavable, fluorescently labelled reversible terminators: synthesis and use in primer extension.

Knapp DC, Serva S, D'Onofrio J, Keller A, Lubys A, Kurg A, Remm M, Engels JW.

Chemistry. 2011 Mar 1;17(10):2903-15. doi: 10.1002/chem.201001952. Epub 2011 Feb 3.


Four-color DNA sequencing with 3'-O-modified nucleotide reversible terminators and chemically cleavable fluorescent dideoxynucleotides.

Guo J, Xu N, Li Z, Zhang S, Wu J, Kim DH, Sano Marma M, Meng Q, Cao H, Li X, Shi S, Yu L, Kalachikov S, Russo JJ, Turro NJ, Ju J.

Proc Natl Acad Sci U S A. 2008 Jul 8;105(27):9145-50. doi: 10.1073/pnas.0804023105. Epub 2008 Jun 30.


Improved nucleotide selectivity and termination of 3'-OH unblocked reversible terminators by molecular tuning of 2-nitrobenzyl alkylated HOMedU triphosphates.

Litosh VA, Wu W, Stupi BP, Wang J, Morris SE, Hersh MN, Metzker ML.

Nucleic Acids Res. 2011 Mar;39(6):e39. doi: 10.1093/nar/gkq1293. Epub 2011 Jan 11.


3'-O-modified nucleotides as reversible terminators for pyrosequencing.

Wu J, Zhang S, Meng Q, Cao H, Li Z, Li X, Shi S, Kim DH, Bi L, Turro NJ, Ju J.

Proc Natl Acad Sci U S A. 2007 Oct 16;104(42):16462-7. Epub 2007 Oct 8.


Design and synthesis of fluorescence-labeled nucleotide with a cleavable azo linker for DNA sequencing.

Tan L, Liu Y, Yang Q, Li X, Wu XY, Gong B, Shen YM, Shao Z.

Chem Commun (Camb). 2016 Jan 18;52(5):954-7. doi: 10.1039/c5cc09131d.


Design and synthesis of a 3'-O-allyl photocleavable fluorescent nucleotide as a reversible terminator for DNA sequencing by synthesis.

Ruparel H, Bi L, Li Z, Bai X, Kim DH, Turro NJ, Ju J.

Proc Natl Acad Sci U S A. 2005 Apr 26;102(17):5932-7. Epub 2005 Apr 13.


Synthesis and evaluations of an acid-cleavable, fluorescently labeled nucleotide as a reversible terminator for DNA sequencing.

Tan L, Liu Y, Li X, Wu XY, Gong B, Shen YM, Shao Z.

Chem Commun (Camb). 2016 Feb 11;52(12):2549-52. doi: 10.1039/c5cc09578f. Epub 2016 Jan 8.


DNA sequencing by synthesis using 3'-O-azidomethyl nucleotide reversible terminators and surface-enhanced Raman spectroscopic detection.

Palla M, Guo W, Shi S, Li Z, Wu J, Jockusch S, Guo C, Russo JJ, Turro NJ, Ju J.

RSC Adv. 2014 Jan 1;4(90):49342-49346.


Termination of DNA synthesis by novel 3'-modified-deoxyribonucleoside 5'-triphosphates.

Metzker ML, Raghavachari R, Richards S, Jacutin SE, Civitello A, Burgess K, Gibbs RA.

Nucleic Acids Res. 1994 Oct 11;22(20):4259-67.


Effective Synthesis of Fluorescently Labeled Morpholino Nucleoside Triphosphate Derivatives.

Tarasenko YV, Abramova TV, Mamatuk VI, Silnikov VN.

Nucleosides Nucleotides Nucleic Acids. 2016;35(1):32-42. doi: 10.1080/15257770.2015.1114125. Epub 2016 Jan 25.


Efficient incorporation of positively charged 2', 3'-dideoxynucleoside-5'-triphosphates by DNA polymerases and their application in 'direct-load' DNA sequencing.

Finn PJ, Bull MG, Xiao H, Phillips PD, Nelson JR, Grossmann G, Nampalli S, McArdle BF, Mamone JA, Flick PK, Fuller CW, Kumar S.

Nucleic Acids Res. 2003 Aug 15;31(16):4769-78.

Supplemental Content

Support Center