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Sildenafil increases muscle protein synthesis and reduces muscle fatigue.

Sheffield-Moore M, Wiktorowicz JE, Soman KV, Danesi CP, Kinsky MP, Dillon EL, Randolph KM, Casperson SL, Gore DC, Horstman AM, Lynch JP, Doucet BM, Mettler JA, Ryder JW, Ploutz-Snyder LL, Hsu JW, Jahoor F, Jennings K, White GR, McCammon SD, Durham WJ.

Clin Transl Sci. 2013 Dec;6(6):463-8. doi: 10.1111/cts.12121. Epub 2013 Oct 29.


Sildenafil improves skeletal muscle oxygenation during exercise in men with intermittent claudication.

Roseguini BT, Hirai DM, Alencar MC, Ramos RP, Silva BM, Wolosker N, Neder JA, Nery LE.

Am J Physiol Regul Integr Comp Physiol. 2014 Aug 15;307(4):R396-404. doi: 10.1152/ajpregu.00183.2014. Epub 2014 Jun 18.


Sildenafil citrate in the treatment of pain in primary dysmenorrhea: a randomized controlled trial.

Dmitrovic R, Kunselman AR, Legro RS.

Hum Reprod. 2013 Nov;28(11):2958-65. doi: 10.1093/humrep/det324. Epub 2013 Aug 6.


Sildenafil therapy for pulmonary hypertension before and after pediatric congenital heart surgery.

Palma G, Giordano R, Russolillo V, Cioffi S, Palumbo S, Mucerino M, Poli V, Vosa C.

Tex Heart Inst J. 2011;38(3):238-42.


Effect of sildenafil on skeletal and cardiac muscle in Becker muscular dystrophy.

Witting N, Kruuse C, Nyhuus B, Prahm KP, Citirak G, Lundgaard SJ, von Huth S, Vejlstrup N, Lindberg U, Krag TO, Vissing J.

Ann Neurol. 2014 Oct;76(4):550-7. doi: 10.1002/ana.24216. Epub 2014 Jul 15.


Sildenafil citrate attenuates the deleterious effects of elevated ammonia.

Arafa MH, Atteia HH.

Toxicol Mech Methods. 2013 Jul;23(6):402-11. doi: 10.3109/15376516.2013.770109. Epub 2013 Mar 27.


Phosphodiesterase 5 (PDE5) inhibition, ANP and NO rapidly reduce epididymal duct contractions, but long-term PDE5 inhibition in vivo does not.

Mietens A, Tasch S, Feuerstacke C, Eichner G, Volkmann J, Schermuly RT, Grimminger F, Müller D, Middendorff R.

Mol Cell Endocrinol. 2012 Feb 26;349(2):145-53. doi: 10.1016/j.mce.2011.09.039. Epub 2011 Oct 2.


Effect of testosterone replacement on response to sildenafil citrate in men with erectile dysfunction: a parallel, randomized trial.

Spitzer M, Basaria S, Travison TG, Davda MN, Paley A, Cohen B, Mazer NA, Knapp PE, Hanka S, Lakshman KM, Ulloor J, Zhang A, Orwoll K, Eder R, Collins L, Mohammed N, Rosen RC, DeRogatis L, Bhasin S.

Ann Intern Med. 2012 Nov 20;157(10):681-91. doi: 10.7326/0003-4819-157-10-201211200-00004.


A randomized open-label trial with a crossover comparison of sexual self-confidence and other treatment outcomes following tadalafil once a day vs. tadalafil or sildenafil on-demand in men with erectile dysfunction.

Rubio-Aurioles E, Porst H, Kim ED, Montorsi F, Hackett G, Morales AM, Stuckey B, Būttner H, West TM, Huynh NN, Lenero E, Burns P, Kopernicky V.

J Sex Med. 2012 May;9(5):1418-29. doi: 10.1111/j.1743-6109.2012.02667.x. Epub 2012 Mar 16.


Summary for patients. Effect of testosterone on response to sildenafil in men with erectile dysfunction.

[No authors listed]

Ann Intern Med. 2012 Nov 20;157(10):I-18. doi: 10.7326/0003-4819-157-10-201211200-00001. No abstract available.


Impact of sildenafil on echocardiographic indices of myocardial performance after the Fontan operation.

Goldberg DJ, French B, Szwast AL, McBride MG, Marino BS, Mirarchi N, Hanna BD, Wernovsky G, Paridon SM, Rychik J.

Pediatr Cardiol. 2012 Jun;33(5):689-96. doi: 10.1007/s00246-012-0196-9. Epub 2012 Feb 14.


Sildenafil improves epicenter vascular perfusion but not hindlimb functional recovery after contusive spinal cord injury in mice.

Myers SA, DeVries WH, Gruenthal MJ, Andres KR, Hagg T, Whittemore SR.

J Neurotrauma. 2012 Feb 10;29(3):528-38. doi: 10.1089/neu.2011.2036. Epub 2011 Dec 15.


The effects of three phosphodiesterase type 5 inhibitors on ejaculation latency time in lifelong premature ejaculators: a double-blind laboratory setting study.

Gökçe A, Halis F, Demirtas A, Ekmekcioglu O.

BJU Int. 2011 Apr;107(8):1274-7. doi: 10.1111/j.1464-410X.2010.09646.x. Epub 2010 Sep 7.


Sildenafil stimulates human trophoblast invasion through nitric oxide and guanosine 3',5'-cyclic monophosphate signaling.

Bolnick JM, Kilburn BA, Bolnick AD, Diamond MP, Singh M, Hertz M, Dai J, Armant DR.

Fertil Steril. 2015 Jun;103(6):1587-95.e1-2. doi: 10.1016/j.fertnstert.2015.02.025. Epub 2015 Mar 23.


The impact of daily sildenafil on levels of soluble molecular markers of endothelial function in plasma in patients with erectile dysfunction.

Konstantinopoulos A, Giannitsas K, Athanasopoulos A, Spathas D, Perimenis P.

Expert Opin Pharmacother. 2009 Feb;10(2):155-60. doi: 10.1517/14656560802678211 .


Potential risks of chronic sildenafil use for priapism in sickle cell disease.

Lane A, Deveras R.

J Sex Med. 2011 Nov;8(11):3193-5. doi: 10.1111/j.1743-6109.2011.02440.x. Epub 2011 Aug 24.


Acute pulmonary hypertension in infants and children: cGMP-related drugs.

Fraisse A, Wessel DL.

Pediatr Crit Care Med. 2010 Mar;11(2 Suppl):S37-40. doi: 10.1097/PCC.0b013e3181c8e6e9. Review.


PhosphdiesteRasE-5 Inhibition to Improve CLinical Status and EXercise Capacity in Diastolic Heart Failure (RELAX) trial: rationale and design.

Redfield MM, Borlaug BA, Lewis GD, Mohammed SF, Semigran MJ, Lewinter MM, Deswal A, Hernandez AF, Lee KL, Braunwald E; Heart Failure Clinical Research Network.

Circ Heart Fail. 2012 Sep 1;5(5):653-9. No abstract available.

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