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Items: 1 to 20 of 102

1.

Thirteen-week oral dose toxicity study of Oligonol containing oligomerized polyphenols extracted from lychee and green tea.

Kitadate K, Homma K, Roberts A, Maeda T.

Regul Toxicol Pharmacol. 2014 Feb;68(1):140-6. doi: 10.1016/j.yrtph.2013.12.001. Epub 2013 Dec 8.

PMID:
24326174
2.

Acute, subchronic and genotoxicity studies conducted with Oligonol, an oligomerized polyphenol formulated from lychee and green tea extracts.

Fujii H, Nishioka H, Wakame K, Magnuson BA, Roberts A.

Food Chem Toxicol. 2008 Dec;46(12):3553-62. doi: 10.1016/j.fct.2008.06.005. Epub 2008 Jun 18. Erratum in: Food Chem Toxicol. 2010 May;48(5):1417.

PMID:
18848969
3.

Evaluation of the safety and toxicity of the oligomerized polyphenol Oligonol.

Fujii H, Sun B, Nishioka H, Hirose A, Aruoma OI.

Food Chem Toxicol. 2007 Mar;45(3):378-87. Epub 2006 Sep 16.

PMID:
17081671
4.

Comparative efficacy of oligonol, catechin and (-)-epigallocatechin 3-O-gallate in modulating the potassium bromate-induced renal toxicity in rats.

Nishioka H, Fujii H, Sun B, Aruoma OI.

Toxicology. 2006 Sep 21;226(2-3):181-7. Epub 2006 Jul 7.

PMID:
16916569
5.

Comparison of the effect of oligonol, a new lychee fruit-derived low molecular form of polyphenol, and epigallocatechin-3-gallate on lipolysis in rat primary adipocytes.

Ogasawara J, Kitadate K, Nishioka H, Fujii H, Sakurai T, Kizaki T, Izawa T, Ishida H, Ohno H.

Phytother Res. 2011 Mar;25(3):467-71. doi: 10.1002/ptr.3296. Epub 2010 Sep 9.

PMID:
20830699
6.
7.
8.

Flavanol-rich lychee fruit extract alleviates diet-induced insulin resistance via suppressing mTOR/SREBP-1 mediated lipogenesis in liver and restoring insulin signaling in skeletal muscle.

Liu HW, Wei CC, Chen YJ, Chen YA, Chang SJ.

Mol Nutr Food Res. 2016 Oct;60(10):2288-2296. doi: 10.1002/mnfr.201501064. Epub 2016 Jul 5.

PMID:
27161245
9.

Safety studies on epigallocatechin gallate (EGCG) preparations. Part 2: dermal, acute and short-term toxicity studies.

Isbrucker RA, Edwards JA, Wolz E, Davidovich A, Bausch J.

Food Chem Toxicol. 2006 May;44(5):636-50. Epub 2006 Jan 4.

PMID:
16387402
10.

Evaluation of oral subchronic toxicity of Pu-erh green tea (camellia sinensis var. assamica) extract in Sprague Dawley rats.

Wang D, Meng J, Xu K, Xiao R, Xu M, Liu Y, Zhao Y, Yao P, Yan H, Liu L.

J Ethnopharmacol. 2012 Aug 1;142(3):836-44. doi: 10.1016/j.jep.2012.06.011. Epub 2012 Jun 16.

PMID:
22710291
11.

Safety of oligonol, a highly bioavailable lychee-derived polyphenolic antioxidant, on liver, kidney and heart function in rats.

Thirunavukkarasu M, Zhan L, Wakame K, Fujii H, Moriyama H, Bagchi M.

Toxicol Mech Methods. 2012 Sep;22(7):555-9. doi: 10.3109/15376516.2012.702795. Epub 2012 Jul 23.

PMID:
22694591
12.

Oligonol, a lychee fruit-derived low-molecular form of polyphenol mixture, suppresses inflammatory cytokine production from human monocytes.

Lee N, Shin MS, Kang Y, Park K, Maeda T, Nishioka H, Fujii H, Kang I.

Hum Immunol. 2016 Jun;77(6):512-5. doi: 10.1016/j.humimm.2016.04.011. Epub 2016 Apr 11.

13.

Effects of green tea extract and (-)-epigallocatechin-3-gallate on pharmacokinetics of nadolol in rats.

Misaka S, Miyazaki N, Fukushima T, Yamada S, Kimura J.

Phytomedicine. 2013 Nov 15;20(14):1247-50. doi: 10.1016/j.phymed.2013.07.003. Epub 2013 Aug 3.

PMID:
23920278
14.

Oligonol, a new lychee fruit-derived low-molecular form of polyphenol, enhances lipolysis in primary rat adipocytes through activation of the ERK1/2 pathway.

Ogasawara J, Kitadate K, Nishioka H, Fujii H, Sakurai T, Kizaki T, Izawa T, Ishida H, Ohno H.

Phytother Res. 2009 Nov;23(11):1626-33. doi: 10.1002/ptr.2846.

PMID:
19548254
15.

Oligonol a low molecular weight polyphenol of lychee fruit extract inhibits proliferation of influenza virus by blocking reactive oxygen species-dependent ERK phosphorylation.

Gangehei L, Ali M, Zhang W, Chen Z, Wakame K, Haidari M.

Phytomedicine. 2010 Nov;17(13):1047-56. doi: 10.1016/j.phymed.2010.03.016.

PMID:
20554190
16.

Pharmacokinetics and safety of green tea polyphenols after multiple-dose administration of epigallocatechin gallate and polyphenon E in healthy individuals.

Chow HH, Cai Y, Hakim IA, Crowell JA, Shahi F, Brooks CA, Dorr RT, Hara Y, Alberts DS.

Clin Cancer Res. 2003 Aug 15;9(9):3312-9.

17.

Safety assessment of green tea based beverages and dried green tea extracts as nutritional supplements.

Dekant W, Fujii K, Shibata E, Morita O, Shimotoyodome A.

Toxicol Lett. 2017 Aug 5;277:104-108. doi: 10.1016/j.toxlet.2017.06.008. Epub 2017 Jun 24. Review.

PMID:
28655517
18.

Oligonol, a low-molecular-weight polyphenol derived from lychee fruit, attenuates gluco-lipotoxicity-mediated renal disorder in type 2 diabetic db/db mice.

Park CH, Noh JS, Fujii H, Roh SS, Song YO, Choi JS, Chung HY, Yokozawa T.

Drug Discov Ther. 2015 Feb;9(1):13-22. doi: 10.5582/ddt.2015.01003. Review.

19.

Oligonol, an oligomerized lychee fruit-derived polyphenol, activates the Ras/Raf-1/MEK1/2 cascade independent of the IL-6 signaling pathway in rat primary adipocytes.

Ogasawara J, Kitadate K, Nishioka H, Fujii H, Sakurai T, Kizaki T, Izawa T, Ishida H, Tanno M, Ohno H.

Biochem Biophys Res Commun. 2010 Nov 19;402(3):554-9. doi: 10.1016/j.bbrc.2010.10.082. Epub 2010 Oct 23.

PMID:
20974109
20.

Green tea extract-induced lethal toxicity in fasted but not in nonfasted dogs.

Wu KM, Yao J, Boring D.

Int J Toxicol. 2011 Feb;30(1):19-20. doi: 10.1177/1091581810387445. Epub 2010 Nov 22.

PMID:
21098339

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